Contents: 1. A Brief History of Immunologic Thinking: Is it Time for Yin and Yang? -- 1.1 Koch’s Postulates -- 1.2 Aristotle’s Laws of Logical Argument -- 1.3 Antigens and T-Cell Responses -- 1.4 Thinking About the Immune System -- 1.5 Fuzzy T-Cell Model -- 1.6 Acknowledgment -- 2. General Aspects of Modeling Tumor Growth and Immune Response -- 2.1 Introduction -- 2.2 What is a Mathematical Model? -- 2.3 Introduction to Deterministic Tumor (or Spheroid) Growth Models -- 2.4 A Predator-Prey Approach -- 2.5 A Model of Tumor Cell/Immune System Interaction -- 2.6 Models, Metaphors and Similes: Some Alternative Paradigms -- 2.7 References -- 2.8 Appendices -- 3. Mathematical Modeling of Tumor Growth Kinetics -- 3.1 Introduction -- 3.2 Tumor Growth as a Dynamical System -- 3.3 The Gompertz Model -- 3.4 The Logistic Model -- 3.5 Models of von Bertalanffy -- 3.6 Tumor Growth Modeled by Specific Mechanisms -- 3.7 Mathematical Models and Measured Growth Curves -- 3.8 Concluding Outlooks -- 3.9 Acknowledgment -- 3.10 References -- 4. Tumor Immune System Interactions: The Kinetic Cellular Theory -- 4.1 Introduction -- 4.2 A Concise Guide to the Literature -- 4.3 Guidelines: From Observation to Simulation -- 4.4 Cell Population and Activity -- 4.5 Modeling Cell Interactions -- 4.6 Evolution Kinetic Equations -- 4.7 Experimental Activity -- 4.8 Simulation and Validation Problems -- 4.9 Remarks Addressed to Applied Mathematicians -- 4.10 Perspectives -- 4.11 References -- 5. From Mutation to Metastasis: The Mathematical Modelling of the Stages of Tumour Development -- 5.1 Introduction -- 5.2 Avascular Tumour Growth: The Multicell Spheroid Model -- 5.3 Thmour Angiogenesis. Capillary Sprout Formation and Growth -- 5.4 Vascular Tumour Growth -- 5.5 Discussion and Conclusions -- 5.6 References -- 6. Basic Models of Tumor-Immune System Interactions Identification, Analysis and Predictions -- 6.1 Introduction -- 6.2 Kinetics Models of Cellular Cytotoxic Reactions at the Effector Stage of Immune Response -- 6.3 Regulatory Cells at the Effector Stage of the Cellular Immune Response -- 6.4 Modeling of the Recognition Mechanisms of Thmor Cells by NK-like Cells -- 6.5 Switch of Cytolytic Mechanisms: Effector Cells, Target Cells and Bispecific Regulating Molecules -- 6.6 Propagation and Interaction of Tumor Specific Macromolecules in Multicellular Tumors -- 6.7 Conclusion -- 6.8 Acknowledgment -- 6.9 References -- 7. Tumor Heterogeneity and Growth Control -- 7.1 Introduction -- 7.2 The Goal -- 7.3 The Plan -- 7.4 The Foundation and Tools -- 7.5 The Structure -- 7.6 Conclusions -- 7.7 References -- 8. Biological Glossary

Dimensions: unknown

Edition: 1st ed. 1997.

Extent: 1 online resource (XVI, 344 p.)

File format: multiple file formats

Form of item: online

Isbn: 9780817681197

Level of compression: uncompressed

Media category: computer

Media MARC source: rdamedia

Media type code

Other control number: 10.1007/978-0-8176-8119-7

Quality assurance targets: absent

Record ID: 99541500702042

Reformatting quality: access

Specific material designation: remote

System control number

(CKB)3400000000087451
(DE-He213)978-0-8176-8119-7
(SSID)ssj0001298666
(PQKBManifestationID)11855957
(PQKBTitleCode)TC0001298666
(PQKBWorkID)11242436
(PQKB)10666835
(MiAaPQ)EBC3072026
(EXLCZ)993400000000087451

Context

Context of A Survey of Models for Tumor-Immune System Dynamics, by John A. Adam, Nicola Bellomo, (electronic resource)

Context

Item

Instantiates