The Resource Transgenics in endocrinology, edited by Martin M. Matzuk, Chester W. Brown, and T. Rajendra Kumar, (electronic resource)

Transgenics in endocrinology, edited by Martin M. Matzuk, Chester W. Brown, and T. Rajendra Kumar, (electronic resource)

Label
Transgenics in endocrinology
Title
Transgenics in endocrinology
Statement of responsibility
edited by Martin M. Matzuk, Chester W. Brown, and T. Rajendra Kumar
Contributor
Subject
Genre
Language
eng
Summary
Transgenic mouse technology, including embryonic stem cell and gene knockout techniques, has revolutionized the study of endocrinology by giving endocrinologists an effective set of tools for understanding endocrine physiology and pathology in vivo. In Transgenics in Endocrinology, a panel of expert clinical and basic investigators summarize the state-of-the-art in the use of this powerful technology in a broad range of endocrinological applications. These applications include studies of mammalian sexual differentiation, steroidogenesis, progesterone action in vivo, normal mammary gland development, oxytocin and vasopressin, regulation and function, skeletal biology, and prostate cancer. There are also transgenic studies of the control of ovarian function, the Bcl2 gene family, c-kit/kit ligand axis in mammalian gametogenesis, prolactin and the prolactin receptor, insulin and insulin-like growth factors, and overexpression and targeted disruption of genes involved in the control of growth, food intake, and obesity. Up-to-date and comprehensive, Transgenics in Endocrinology reviews the most recent developments in the analysis of endocrine physiology, and its pathologies, through mouse models, and provides a host of creative approaches to better understand the complex processes characteristic of hormonal systems
Member of
Action
digitized
Cataloging source
N$T
Dewey number
573.4/19
Illustrations
illustrations
Index
index present
LC call number
QP187.3.M64
LC item number
T73 2001eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2001 K-899
  • WK 20
NLM item number
T7725 2001
http://library.link/vocab/relatedWorkOrContributorName
  • Matzuk, Martin M
  • Brown, Chester W
  • Kumar, T. Rajendra
Series statement
Contemporary endocrinology
http://library.link/vocab/subjectName
  • Molecular endocrinology
  • Transgenic mice
  • Transgenic organisms
  • Endocrinology
  • Endocrinology
  • Research Design
  • Mice, Transgenic
  • SOCIAL SCIENCE
Label
Transgenics in endocrinology, edited by Martin M. Matzuk, Chester W. Brown, and T. Rajendra Kumar, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-102-2
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1 Germline Genetic Engineering Techniques in Endocrinology -- 2 The Transgenic Mouse in Studies of Mammalian Sexual Differentiation -- 3 The In Vivo Function of Müllerian-Inhibiting Substance During Mammalian Sexual Development -- 4 Control of Ovarian Function -- 5 Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression -- 6 Functional Analysis of the Bcl2 Gene Family in Transgenic Mice -- 7 The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis -- 8 Gene Knockout Approaches to Steroidogenesis -- 9 The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo -- 10 Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development -- 11 Prolactin and the Prolactin Receptor -- 12 Transgenic Models for Oxytocin and Vasopressin -- 13 Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function -- 14 Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation -- 15 Transgenic Analysis of the Proopiomelanocortin Neuroendocrine System -- 16 Overexpression and Targeted Disruption of Genes Involved in the Control of Growth, Food Intake, and Obesity -- 17 Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors -- 18 Use of Transgenic Animals in Skeleton Biology -- 19 Transgenic Mouse Models of Prostate Cancer -- 20 Neural- and Endocrine-Cell-Specific Immortalization Using Transgenic Approaches
Dimensions
unknown
Extent
1 online resource (x, 485 p.)
File format
unknown
Form of item
online
Isbn
9781592591022
Isbn Type
(electronic bk.)
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-102-2
Other physical details
ill.
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic reproduction.
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)171122475
  • (OCoLC)ocn171122475
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Label
Transgenics in endocrinology, edited by Martin M. Matzuk, Chester W. Brown, and T. Rajendra Kumar, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-102-2
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1 Germline Genetic Engineering Techniques in Endocrinology -- 2 The Transgenic Mouse in Studies of Mammalian Sexual Differentiation -- 3 The In Vivo Function of Müllerian-Inhibiting Substance During Mammalian Sexual Development -- 4 Control of Ovarian Function -- 5 Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression -- 6 Functional Analysis of the Bcl2 Gene Family in Transgenic Mice -- 7 The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis -- 8 Gene Knockout Approaches to Steroidogenesis -- 9 The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo -- 10 Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development -- 11 Prolactin and the Prolactin Receptor -- 12 Transgenic Models for Oxytocin and Vasopressin -- 13 Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function -- 14 Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation -- 15 Transgenic Analysis of the Proopiomelanocortin Neuroendocrine System -- 16 Overexpression and Targeted Disruption of Genes Involved in the Control of Growth, Food Intake, and Obesity -- 17 Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors -- 18 Use of Transgenic Animals in Skeleton Biology -- 19 Transgenic Mouse Models of Prostate Cancer -- 20 Neural- and Endocrine-Cell-Specific Immortalization Using Transgenic Approaches
Dimensions
unknown
Extent
1 online resource (x, 485 p.)
File format
unknown
Form of item
online
Isbn
9781592591022
Isbn Type
(electronic bk.)
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-102-2
Other physical details
ill.
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic reproduction.
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)171122475
  • (OCoLC)ocn171122475
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

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