The Resource Transgenic and knockout models of neuropsychiatric disorders, edited by Gene S. Fisch, Jonathan Flint, (electronic resource)

Transgenic and knockout models of neuropsychiatric disorders, edited by Gene S. Fisch, Jonathan Flint, (electronic resource)

Label
Transgenic and knockout models of neuropsychiatric disorders
Title
Transgenic and knockout models of neuropsychiatric disorders
Statement of responsibility
edited by Gene S. Fisch, Jonathan Flint
Contributor
Subject
Genre
Language
eng
Summary
Neuroscientists are now establishing meaningful genotype-phenotype relationships for complex neurobehavioral and neuropsychiatric disorders and even creating animal models for these dysfunctions. These developments have made it imperative to know when such transgenic and knockout models are valid for the human disorders they represent. In Transgenic and Knockout Models of Neuropsychiatric Disorders, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, as well as speech disorders, and disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder. Timely introductory articles debate the alleged continuity of species of human and infrahuman behavior (Darwin), the utility of infrahuman animals in understanding human behavior and psychiatric disease, and the suitability of nonhuman models of complex neuropsychiatric dysfunctions involving language. Comprehensive and systematic, Transgenic and Knockout Models of Neuropsychiatric Disorders offers a clear assessment of whether genetic abnormalities produced from infrahuman models manifest the neuropsychiatric disorders to which they correspond in humans and how best they may be used to carry out successful research today
Member of
Cataloging source
COO
Dewey number
616.8
Illustrations
illustrations
Index
index present
LC call number
RC455.4.A54
LC item number
T73 2006
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2006 E-983
  • WM 140
NLM item number
T772 2006
http://library.link/vocab/relatedWorkOrContributorName
  • Fisch, Gene S
  • Flint, Jonathan
Series statement
Contemporary clinical neuroscience
http://library.link/vocab/subjectName
  • Mental illness
  • Mental illness
  • Transgenic mice
  • Mental Disorders
  • Mental Disorders
  • Animal Experimentation
  • Disease Models, Animal
  • Mice, Transgenic
  • Psychology, Experimental
  • HEALTH & FITNESS
  • MEDICAL
  • Biomédecine
  • Sciences de la vie
  • Mental illness
  • Transgenic mice
  • Mental Disorders
  • Mental Disorders
  • Animal experimentation
  • Disease Models, Animal
  • Mice, Transgenic
  • Psychology, Experimental
  • Electronic books
  • Mental illness
Label
Transgenic and knockout models of neuropsychiatric disorders, edited by Gene S. Fisch, Jonathan Flint, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59745-058-4
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Transgenic and knockout models of psychiatric disorders: introduction, history, and assessment / Gene S. Fisch -- Transgenic mouse models and human psychiatric disease / Jonathan Flint -- Transgenic and knockout mouse models: the problem of language / Linda J. Hayes and Diana Delgado -- If only they could talk: genetic mouse models for psychiatric disorders / Trevor Humby and Lawrence Wilkinson
  • Spinocerebellar ataxia type 1: lessons from modeling a movement disease in mice / Harry T. Orr -- Mouse models of hereditary mental retardation / Hans Welzl [and others] -- How can studies of animals help to uncover the roles of genes implicated in human speech and language disorders? / Simon E. Fisher -- Animal models of autism: proposed behavioral paradigms and biological studies / Thomas Bourgeron, Stéphane Jamain, and Sylvie Granon
  • Genetic mouse models of psychiatric disorders: advantages, limitations, and challenges / Joseph A. Gogos and Maria Karayiorgou -- Animal models of psychosis / Stephen I. Deutsch [and others] -- Animal models of anxiety: the ethological perspective / Robert Gerlai, Robert Blanchard, and Caroline Blanchard -- Modeling human anxiety and depression in mutant mice / Andrew Holmes and John F. Cryan -- Mutant mouse models of bipolar disorder: are there any? / Anneloes Dirks, Lucianne Groenink, and Berend Olivier
Dimensions
unknown
Extent
1 online resource (xii, 296 pages)
Form of item
online
Isbn
9781597450584
Isbn Type
(e-ISBN)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
9786610832071
Other physical details
illustrations.
Specific material designation
remote
Stock number
83207
System control number
  • (OCoLC)172717643
  • (OCoLC)ocn172717643
Label
Transgenic and knockout models of neuropsychiatric disorders, edited by Gene S. Fisch, Jonathan Flint, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59745-058-4
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Transgenic and knockout models of psychiatric disorders: introduction, history, and assessment / Gene S. Fisch -- Transgenic mouse models and human psychiatric disease / Jonathan Flint -- Transgenic and knockout mouse models: the problem of language / Linda J. Hayes and Diana Delgado -- If only they could talk: genetic mouse models for psychiatric disorders / Trevor Humby and Lawrence Wilkinson
  • Spinocerebellar ataxia type 1: lessons from modeling a movement disease in mice / Harry T. Orr -- Mouse models of hereditary mental retardation / Hans Welzl [and others] -- How can studies of animals help to uncover the roles of genes implicated in human speech and language disorders? / Simon E. Fisher -- Animal models of autism: proposed behavioral paradigms and biological studies / Thomas Bourgeron, Stéphane Jamain, and Sylvie Granon
  • Genetic mouse models of psychiatric disorders: advantages, limitations, and challenges / Joseph A. Gogos and Maria Karayiorgou -- Animal models of psychosis / Stephen I. Deutsch [and others] -- Animal models of anxiety: the ethological perspective / Robert Gerlai, Robert Blanchard, and Caroline Blanchard -- Modeling human anxiety and depression in mutant mice / Andrew Holmes and John F. Cryan -- Mutant mouse models of bipolar disorder: are there any? / Anneloes Dirks, Lucianne Groenink, and Berend Olivier
Dimensions
unknown
Extent
1 online resource (xii, 296 pages)
Form of item
online
Isbn
9781597450584
Isbn Type
(e-ISBN)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
9786610832071
Other physical details
illustrations.
Specific material designation
remote
Stock number
83207
System control number
  • (OCoLC)172717643
  • (OCoLC)ocn172717643

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