The Resource To grasp the essence of life : a history of molecular biology, by Rudolf Hausmann ; translated by Celma and Rudolf Hausmann

To grasp the essence of life : a history of molecular biology, by Rudolf Hausmann ; translated by Celma and Rudolf Hausmann

Label
To grasp the essence of life : a history of molecular biology
Title
To grasp the essence of life
Title remainder
a history of molecular biology
Statement of responsibility
by Rudolf Hausmann ; translated by Celma and Rudolf Hausmann
Creator
Subject
Genre
Language
  • eng
  • ger
  • eng
Summary
50 years of DNA double helix; what was before, and afterwards The present book, although written mainly for science students and research scientists, is also aimed at those readers who look at science, not for its own sake, but in search of a better understanding of our world in general. What were the fundamental questions asked by the early pioneers of molecular biology? What made them tick for decades, trying to elucidate the basic mechanisms of heredity and life itself? In each chapter, the development of a particular aspect of modern biology is described in a historical and logical context, not missing to take into account human aspects of the protagonists of the story. At the end of each chapter, there are some excursus with additional information, technical and otherwise, which can be read separately. The book is enriched with many illustrations, including facsimile reproductions from the original descriptions of key experiments
Member of
Cataloging source
GW5XE
http://library.link/vocab/creatorName
Hausmann, Rudolf
Dewey number
572.8
Illustrations
illustrations
Index
index present
Language note
The present English version is an updated and slightly expanded translation of the German edition: " ... und wollten versuchen, das Leben zu verstehen ... Betrachtungen zur Geschichte der Molekularbiologie" Wissenschaftliche Buchgesellschaft Darmstadt; ISBN 3534115759
LC call number
QH506
LC item number
.H37513 2002eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2005 D-918
  • QH 506
NLM item number
H376u 2002
http://library.link/vocab/subjectName
  • Molecular biology
  • Molecular Biology
  • Genomics
  • Moleculaire biologie
  • Molekularbiologie
  • Molecular biology
Label
To grasp the essence of life : a history of molecular biology, by Rudolf Hausmann ; translated by Celma and Rudolf Hausmann
Link
http://dx.doi.org/10.1007/978-94-017-3540-7
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references (pages 293-321) and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • A brief digression: where does the energy come from?
  • Mendel
  • Chromosome maps
  • The early biochemistry of the cell nucleus
  • One Gene--One Enzyme
  • The replica plate technique (Lederberg & Lederberg, 1952)
  • Proof of contact between parental cells during bacterial conjugation--and the discovery of transduction
  • Phages
  • Bacteriophages
  • The quest for the origin of mutations: Luria and Delbruck's fluctuation test
  • Enzymes
  • Phage-directed protein synthesis
  • The Double Helix
  • Double Helix: the Anticlimax
  • A corollary of Watson and Crick's model: the insight that errors in base-pairing can lead to mutations
  • The replication mode of DNA
  • Denaturation, renaturation, and hybridization of DNA
  • Avery? Hershey?
  • The transforming principle is DNA
  • Hershey & Chase's (1952) blender experiment
  • The Code Craze
  • Cell fractionation
  • One mutation alters hemoglobin in only one amino acid
  • Linearity ... Colinearity
  • Protein Synthesis in vitro. How did it all start?
  • Polypeptide synthesis proceeds from the amino- to the carboxy-terminal
  • The Code in vitro
  • How does polypeptide synthesis occur on the ribosome?
  • Inside the Institut Pasteur, Part I: Prophage and the Fertility Factor F
  • Parasites at the genetic level
  • Inside the Institut Pasteur, Part II: Interrupted Mating
  • Emil Fischer, Franz Hofmeister, and the peptide bond
  • Spatial structures of polypeptides
  • X-ray diffraction analysis
  • Pascual Jordan's mistake
  • Genes
  • Escherichia coli: an example of a self-replicating machine
Dimensions
unknown
Extent
1 online resource (xii, 332 pages)
File format
unknown
Form of item
online
Isbn
9789401735407
Isbn Type
(electronic bk.)
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-94-017-3540-7
Other physical details
illustrations
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)861706515
  • (OCoLC)ocn861706515
Label
To grasp the essence of life : a history of molecular biology, by Rudolf Hausmann ; translated by Celma and Rudolf Hausmann
Link
http://dx.doi.org/10.1007/978-94-017-3540-7
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references (pages 293-321) and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • A brief digression: where does the energy come from?
  • Mendel
  • Chromosome maps
  • The early biochemistry of the cell nucleus
  • One Gene--One Enzyme
  • The replica plate technique (Lederberg & Lederberg, 1952)
  • Proof of contact between parental cells during bacterial conjugation--and the discovery of transduction
  • Phages
  • Bacteriophages
  • The quest for the origin of mutations: Luria and Delbruck's fluctuation test
  • Enzymes
  • Phage-directed protein synthesis
  • The Double Helix
  • Double Helix: the Anticlimax
  • A corollary of Watson and Crick's model: the insight that errors in base-pairing can lead to mutations
  • The replication mode of DNA
  • Denaturation, renaturation, and hybridization of DNA
  • Avery? Hershey?
  • The transforming principle is DNA
  • Hershey & Chase's (1952) blender experiment
  • The Code Craze
  • Cell fractionation
  • One mutation alters hemoglobin in only one amino acid
  • Linearity ... Colinearity
  • Protein Synthesis in vitro. How did it all start?
  • Polypeptide synthesis proceeds from the amino- to the carboxy-terminal
  • The Code in vitro
  • How does polypeptide synthesis occur on the ribosome?
  • Inside the Institut Pasteur, Part I: Prophage and the Fertility Factor F
  • Parasites at the genetic level
  • Inside the Institut Pasteur, Part II: Interrupted Mating
  • Emil Fischer, Franz Hofmeister, and the peptide bond
  • Spatial structures of polypeptides
  • X-ray diffraction analysis
  • Pascual Jordan's mistake
  • Genes
  • Escherichia coli: an example of a self-replicating machine
Dimensions
unknown
Extent
1 online resource (xii, 332 pages)
File format
unknown
Form of item
online
Isbn
9789401735407
Isbn Type
(electronic bk.)
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-94-017-3540-7
Other physical details
illustrations
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)861706515
  • (OCoLC)ocn861706515

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