The Resource The ventricular-subventricular zone : a source of oligodendrocytes in the adult brain, topic editors, Oscar Gonzalez-Perez, Jose Manuel Garcia-Verdugo and Adan Aguirre

The ventricular-subventricular zone : a source of oligodendrocytes in the adult brain, topic editors, Oscar Gonzalez-Perez, Jose Manuel Garcia-Verdugo and Adan Aguirre

Label
The ventricular-subventricular zone : a source of oligodendrocytes in the adult brain
Title
The ventricular-subventricular zone
Title remainder
a source of oligodendrocytes in the adult brain
Statement of responsibility
topic editors, Oscar Gonzalez-Perez, Jose Manuel Garcia-Verdugo and Adan Aguirre
Contributor
Editor
Subject
Language
eng
Summary
Demyelinating diseases are characterized by an extensive loss of oligodendrocytes and myelin sheaths from axolemma, which commonly result in disability in young adults. To date, there is no effective treatment against these neurological disorders. In the adult brain, there are neural stem cells (NSCs) that reside within a niche denominated ventricular-subventricular zone (V-SVZ) in the lateral wall of the cerebral ventricles. NSCs give rise to neurons and oligodendrocytes that help preserve cellular homeostasis. Growing evidence indicates that V-SVZ progenitor cells may represent an endogenous source of oligodendrocytes that can be useful to treat demyelinating diseases. This e-Book collected the most recent evidence regarding the mechanisms that modulate the proliferation, migration, quiescence, cell-fate choices and survival of oligodendrocyte precursors generated in the V-SVZ. Herein, we compiled information about the role of Sonic hedgehog, NMDA receptors, ErbB proteins, hemopressin, erythropoietin, osmolarity and microglia in the oligodendrocyte production. Some chapters also describe the role of oligodendrocyte precursors in the preservation of cellular homeostasis, aging and white matter repair. All these information is presented as novel research findings, short communications, and review articles, which were written by experts in the field of oligodendrocyte generation, myelin production and white matter re-myelinatio
Cataloging source
WaSeSS
Illustrations
illustrations
Index
no index present
LC call number
  • QP356.25
  • QP356.25
Literary form
non fiction
Nature of contents
  • standards specifications
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Gonzalez-Perez, Oscar
  • García-Verdugo, José Manuel
  • Aguirre Benítez, Adán
Series statement
Frontiers Research Topics,
http://library.link/vocab/subjectName
  • Brain
  • Neural stem cells
Target audience
specialized
Label
The ventricular-subventricular zone : a source of oligodendrocytes in the adult brain, topic editors, Oscar Gonzalez-Perez, Jose Manuel Garcia-Verdugo and Adan Aguirre
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Extent
1 online resource (104 pages):
Form of item
online
Governing access note
Open Access
Isbn
9782889192687
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Specific material designation
remote
System control number
  • (CKB)3710000000520095
  • (WaSeSS)IndRDA00059090
  • (EXLCZ)993710000000520095
System details
Mode of acesss: internet via World Wide Web
Label
The ventricular-subventricular zone : a source of oligodendrocytes in the adult brain, topic editors, Oscar Gonzalez-Perez, Jose Manuel Garcia-Verdugo and Adan Aguirre
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Extent
1 online resource (104 pages):
Form of item
online
Governing access note
Open Access
Isbn
9782889192687
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Specific material designation
remote
System control number
  • (CKB)3710000000520095
  • (WaSeSS)IndRDA00059090
  • (EXLCZ)993710000000520095
System details
Mode of acesss: internet via World Wide Web

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