Coverart for item
The Resource The role of microenvironment in axonal regeneration : influences of lesion-induced changes and glial implants on the regeneration of the postcommissural fornix, Christine C. Stichel-Gunkel, (electronic resource)

The role of microenvironment in axonal regeneration : influences of lesion-induced changes and glial implants on the regeneration of the postcommissural fornix, Christine C. Stichel-Gunkel, (electronic resource)

Label
The role of microenvironment in axonal regeneration : influences of lesion-induced changes and glial implants on the regeneration of the postcommissural fornix
Title
The role of microenvironment in axonal regeneration
Title remainder
influences of lesion-induced changes and glial implants on the regeneration of the postcommissural fornix
Statement of responsibility
Christine C. Stichel-Gunkel
Creator
Subject
Genre
Language
eng
Summary
Since the pioneering studies of Ramon y Cajal the inability of lesioned adult CNS axons to regenerate has been well established. During the past years advancements in molecular, cellular and biochemical knowledge have provided new insights into the extrinsic mechanims underlying regeneration failure. The rapid progress in this field has already led to the development of new concepts for therapeutic manipulations. This book provides a comprehensive overview of structural and molecular changes induced by an invasive CNS lesion and their involvements in regeneration processes. Moreover, it demonstrates the strong growth-promoting actitivies of implanted glial cells. The data is discussed in relation to current knowledge on the mechanisms of axonal degeneration and regeneration and in terms of their relevance for the development of novel therapeutic strategies
Member of
Cataloging source
VT2
http://library.link/vocab/creatorDate
1960-
http://library.link/vocab/creatorName
Stichel-Gunkel, Christine C.
Dewey number
  • 571 s
  • 573.8/519
Illustrations
illustrations
Index
index present
LC call number
RC321-580
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1 AD433K v.137 1997
  • WL 102.5 S854r 1997
Series statement
Advances in anatomy, embryology, and cell biology
Series volume
vol. 137
http://library.link/vocab/subjectName
  • Nervous system
  • Axons
  • Neuroglia
  • Axons
  • Nerve Regeneration
  • Tissue Transplantation
  • Axons
  • Nervous system
  • Neuroglia
Label
The role of microenvironment in axonal regeneration : influences of lesion-induced changes and glial implants on the regeneration of the postcommissural fornix, Christine C. Stichel-Gunkel, (electronic resource)
Link
http://dx.doi.org/10.1007/978-3-642-60781-3
Instantiates
Publication
Bibliography note
Includes bibliographical references (p. 61-77) and index
Contents
Contents: Introduction;- Axonal regeneration in the adult mammalian CNS -- Aims of the study -- Materials and methods -- Cell culture techniques -- Surgical procedures -- Tissue procedures -- Tissue processing -- Histological methods -- Immunohistochemical methods -- In situ-Hybridisation -- Quantitative analysis -- Results -- Unlesioned postcommissural fornix -- Sequence of cellular and molecular reactions following axonal transection -- Glial cell implantations -- Discussion -- Role of lesion-induced cellular and molecular changes in degeneration and regeneration -- The impact of glial implants on axonal regeneration -- Summary and perspectives -- References;- Subject Index
Dimensions
unknown
Extent
1 online resource (viii, 81 p.)
Form of item
online
Isbn
9783642607813
Isbn Type
(electronic bk.)
Lccn
97010368
Other physical details
ill.
Specific material designation
remote
System control number
  • (OCoLC)828776205
  • (OCoLC)ocn828776205
Label
The role of microenvironment in axonal regeneration : influences of lesion-induced changes and glial implants on the regeneration of the postcommissural fornix, Christine C. Stichel-Gunkel, (electronic resource)
Link
http://dx.doi.org/10.1007/978-3-642-60781-3
Publication
Bibliography note
Includes bibliographical references (p. 61-77) and index
Contents
Contents: Introduction;- Axonal regeneration in the adult mammalian CNS -- Aims of the study -- Materials and methods -- Cell culture techniques -- Surgical procedures -- Tissue procedures -- Tissue processing -- Histological methods -- Immunohistochemical methods -- In situ-Hybridisation -- Quantitative analysis -- Results -- Unlesioned postcommissural fornix -- Sequence of cellular and molecular reactions following axonal transection -- Glial cell implantations -- Discussion -- Role of lesion-induced cellular and molecular changes in degeneration and regeneration -- The impact of glial implants on axonal regeneration -- Summary and perspectives -- References;- Subject Index
Dimensions
unknown
Extent
1 online resource (viii, 81 p.)
Form of item
online
Isbn
9783642607813
Isbn Type
(electronic bk.)
Lccn
97010368
Other physical details
ill.
Specific material designation
remote
System control number
  • (OCoLC)828776205
  • (OCoLC)ocn828776205

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