The Resource The pathogenesis of neurodegenerative disorders, edited by Mark P. Mattson, (electronic resource)

The pathogenesis of neurodegenerative disorders, edited by Mark P. Mattson, (electronic resource)

Label
The pathogenesis of neurodegenerative disorders
Title
The pathogenesis of neurodegenerative disorders
Statement of responsibility
edited by Mark P. Mattson
Contributor
Subject
Genre
Language
eng
Summary
Recent scientific advances have dramatically expanded our understanding of the molecular, genetic, and environmental factors that either cause or contribute to a wide variety of age-related neurodegenerative disorders. In Pathogenesis of Neurodegenerative Disorders, leading experts detail the cellular and molecular cascades that cause selective degeneration of neuronal populations, and illuminate those factors that are critical to the facilitation or suppression of these neuropathologic processes. Working from studies of human patients, as well as from cell culture and animal models, the authors demonstrate a heretofore unrecognized convergence of the causative pathogenetic mechanisms for many clinically distinct neurological disorders. At center stage are the biochemical and molecular cascades that will ultimately lead to neuronal death-cascades involving oxyradical production, aberrant regulation of cellular ion homeostasis, activation of specific proteases, and activation of a stereotyped sequence of events involving mitochondrial dysfunction. Individual chapters examine how these mechanisms-along with genetic and environmental factors-operate in Alzheimer's and Parkinson's diseases, Down's syndrome, amyotropic lateral sclerosis, ischemic stroke, spinal cord injury, and Duchenne muscular dystrophy. Pioneering and richly insightful, Pathogenesis of Neurodegenerative Disorders offers a critical and integrative summary of the cutting-edge research findings that illuminate the common genetic, cellular, and molecular bases of many neurological disorders today that promise powerful new preventive and treatment approaches in future
Member of
Action
digitized
Cataloging source
N$T
Dewey number
616.8/047
Illustrations
illustrations
Index
index present
LC call number
RC365
LC item number
.P385 2001eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
WL 359
NLM item number
P297 2001
http://library.link/vocab/relatedWorkOrContributorName
Mattson, Mark Paul
Series statement
Contemporary neuroscience
http://library.link/vocab/subjectName
  • Nervous system
  • Neurodegenerative Diseases
  • Neurodegenerative Diseases
  • Sistema nervioso
  • HEALTH & FITNESS
  • MEDICAL
  • Maladies neurodégénératives
  • Maladies neurodégénératives héréditaires
  • Système nerveux
  • Pathogenese
  • Nervendegeneration
Label
The pathogenesis of neurodegenerative disorders, edited by Mark P. Mattson, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-106-0
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Mechanisms of neuronal apoptosis and excitotoxicity / Mark P. Mattson -- Oxidative alterations in neuroegenerative diseases / William R. Markesbery, Thomas J. Montine, and Mark A. Lovell -- Parkinson's disease / M.T. Silva and A.H.V. Schapira -- Scope of trinucleotide repeat disorders / Shoji Tsuji -- Mechanisms of neuronal death in huntington's disease / Vassilis E. Koliatsos [and others] -- Cellular and molecular mechanisms underlying synaptic degeneration and neuronal death in alzheimer's disease / Mark P. Mattson, Ward A. Pedersen, and Carsten Culmsee -- Oxidative stress in down syndrome / Rocco C. Iannello and Ismail Kola -- Pathogenesis of amyotrophic lateral sclerosis / Stanley H. Appel and R. Glenn Smith -- Experimental genetics as a tool for understanding pathogenesis of ALS / Philip C. Wong, Donald L. Price, and Jamuna Subramaniam -- Pathognesis of ischemic stroke / Mark P. Mattson and Carsten Culmsee -- Spinal-cord injury / Isabel Klusman and Martin E. Schwab -- Pathognesis of duchenne muscular dystrophy / Edward A. Burgon and Kay E. Davies
Dimensions
unknown
Extent
1 online resource (x, 294 pages)
Form of item
online
Isbn
9781592591060
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-106-0
Other physical details
illustrations.
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
  • (OCoLC)51480769
  • (OCoLC)ocm51480769
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Label
The pathogenesis of neurodegenerative disorders, edited by Mark P. Mattson, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-106-0
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Mechanisms of neuronal apoptosis and excitotoxicity / Mark P. Mattson -- Oxidative alterations in neuroegenerative diseases / William R. Markesbery, Thomas J. Montine, and Mark A. Lovell -- Parkinson's disease / M.T. Silva and A.H.V. Schapira -- Scope of trinucleotide repeat disorders / Shoji Tsuji -- Mechanisms of neuronal death in huntington's disease / Vassilis E. Koliatsos [and others] -- Cellular and molecular mechanisms underlying synaptic degeneration and neuronal death in alzheimer's disease / Mark P. Mattson, Ward A. Pedersen, and Carsten Culmsee -- Oxidative stress in down syndrome / Rocco C. Iannello and Ismail Kola -- Pathogenesis of amyotrophic lateral sclerosis / Stanley H. Appel and R. Glenn Smith -- Experimental genetics as a tool for understanding pathogenesis of ALS / Philip C. Wong, Donald L. Price, and Jamuna Subramaniam -- Pathognesis of ischemic stroke / Mark P. Mattson and Carsten Culmsee -- Spinal-cord injury / Isabel Klusman and Martin E. Schwab -- Pathognesis of duchenne muscular dystrophy / Edward A. Burgon and Kay E. Davies
Dimensions
unknown
Extent
1 online resource (x, 294 pages)
Form of item
online
Isbn
9781592591060
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-106-0
Other physical details
illustrations.
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
  • (OCoLC)51480769
  • (OCoLC)ocm51480769
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

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