The Resource The BRICHOS domain : its proproteins and functions, Jenny Presto, Jan Johansson

The BRICHOS domain : its proproteins and functions, Jenny Presto, Jan Johansson

Label
The BRICHOS domain : its proproteins and functions
Title
The BRICHOS domain
Title remainder
its proproteins and functions
Statement of responsibility
Jenny Presto, Jan Johansson
Creator
Contributor
Author
Subject
Genre
Language
eng
Summary
This Brief summarizes the current research on the novel BRICHOS domain, which is a chaperone domain found in a variety of proteins and is shown to exhibit anti-amyloidogenic chaperone-like functions. The BRICHOS domain is defined from sequence similarities, lacks established physiological function(s) and is found about 10 distantly related pro-protein families, several of which are associated with human disease. In this work, the authors review the mechanism by which BRICHOS inhibits Alø aggregation and examine recent results from in vivo experiments where BRICHOS inhibits Alø aggregation and toxicity in Drosophila melanogaster. BRICHOS is one of nature℗þs (more specific) ways to protect against fibril formation, and exploring the potential of using the BRICHOS domain in the fight against Alzeimer's Disease and other amyloid diseases seems highly relevant. This brief is useful for newcomers to this field or researchers in related fields wishing to gain a quick overview of the latest findings
Member of
Cataloging source
N$T
http://library.link/vocab/creatorName
Presto, Jenny
Dewey number
574.19245
Index
no index present
LC call number
QP551
LC item number
.P74 2015eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU 55.9
http://library.link/vocab/relatedWorkOrContributorName
Johansson, Jan
Series statement
SpringerBriefs in molecular science. Protein folding and structure
http://library.link/vocab/subjectName
  • Protein folding
  • Proteins
  • SCIENCE
  • Protein folding
  • Proteins
  • Chemistry
  • Bioorganic Chemistry
  • Protein Structure
  • Protein Folding
  • Proteins
  • Biochemistry
Label
The BRICHOS domain : its proproteins and functions, Jenny Presto, Jan Johansson
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-319-16564-6
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction to BRICHOS Superfamily -- BRICHOS in proSP-C -- Proteins with a BRICHOS Domain -- AÝ Amyloid Formation in Alzheimer's disease -- In vivo Effect of BRICHOS on AÝ Aggregation and Toxicity
Dimensions
unknown
Extent
1 online resource.
File format
unknown
Form of item
online
Isbn
9783319165646
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-3-319-16564-6
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)904959422
  • (OCoLC)ocn904959422
Label
The BRICHOS domain : its proproteins and functions, Jenny Presto, Jan Johansson
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-319-16564-6
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction to BRICHOS Superfamily -- BRICHOS in proSP-C -- Proteins with a BRICHOS Domain -- AÝ Amyloid Formation in Alzheimer's disease -- In vivo Effect of BRICHOS on AÝ Aggregation and Toxicity
Dimensions
unknown
Extent
1 online resource.
File format
unknown
Form of item
online
Isbn
9783319165646
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-3-319-16564-6
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)904959422
  • (OCoLC)ocn904959422

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