The Resource Telomeres and telomerase : methods and protocols, edited by John A. Double and Michael J. Thompson, (electronic resource)

Telomeres and telomerase : methods and protocols, edited by John A. Double and Michael J. Thompson, (electronic resource)

Label
Telomeres and telomerase : methods and protocols
Title
Telomeres and telomerase
Title remainder
methods and protocols
Statement of responsibility
edited by John A. Double and Michael J. Thompson
Contributor
Subject
Genre
Language
eng
Summary
The discovery of telomerase expression in a majority of tumors and the recognition of its potential role in the aging process has dramatically raised its profile as a target for therapeutic intervention. In Telomeres and Telomerase: Methods and Protocols, John A. Double and Michael J. Thompson have collected a critically important series of novel and essential techniques for studying telomeres and telomerase. These readily reproducible protocols provide cutting-edge tools to identify, measure, and analyze telomeres, to determine telomerase expression at the RNA level, to determine telomerase activity, and to detect potential modifiers of this activity. The techniques for assaying telomerase activity range from standard radiological TRAP assays to nonradioactive methods, from non-PCR-based methods to techniques using real-time PCR. Written by investigators who have used the methods extensively, each protocol includes step-by-step instructions, tips on avoiding pitfalls, and invaluable notes that make all the difference to successful experimental outcomes. Broad-ranging and highly practical, Telomeres and Telomerase: Methods and Protocols provides molecular and cell biologists, cancer researchers, and cellular pathologists with the core array of productive techniques needed today to develop telomerase inhibitors and clinically valuable diagnostic/prognostic telomerase markers
Member of
Cataloging source
N$T
Dewey number
572.8/7
Illustrations
illustrations
Index
index present
LC call number
QP606.T44
LC item number
T45 2002eb
Literary form
non fiction
Nature of contents
  • standards specifications
  • bibliography
NLM call number
  • W1
  • QH 600.3
NLM item number
  • ME9616J v.191
  • T2777 2002
http://library.link/vocab/relatedWorkOrContributorName
  • Double, John A
  • Thompson, Michael J
Series statement
Methods in molecular biology
Series volume
v. 191
http://library.link/vocab/subjectName
  • Telomerase
  • Telomere
  • Telomere
  • Telomerase
  • SCIENCE
  • Telomerase
  • Telomere
Label
Telomeres and telomerase : methods and protocols, edited by John A. Double and Michael J. Thompson, (electronic resource)
Link
http://dx.doi.org/10.1385/1592591892
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Dimensions
unknown
Extent
1 online resource (xi, 221 pages)
Form of item
online
Isbn
9780896036574
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Specific material designation
remote
System control number
  • (OCoLC)50175113
  • (OCoLC)ocm50175113
Label
Telomeres and telomerase : methods and protocols, edited by John A. Double and Michael J. Thompson, (electronic resource)
Link
http://dx.doi.org/10.1385/1592591892
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Dimensions
unknown
Extent
1 online resource (xi, 221 pages)
Form of item
online
Isbn
9780896036574
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Specific material designation
remote
System control number
  • (OCoLC)50175113
  • (OCoLC)ocm50175113

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