The Resource Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes, Lena Josefine Daumann

Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes, Lena Josefine Daumann

Label
Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes
Title
Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes
Statement of responsibility
Lena Josefine Daumann
Creator
Author
Subject
Genre
Language
eng
Summary
Lena Daumanns's thesis describes structural and functional studies of the enzyme Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. It also examines the properties of small mimics of this enzyme and related binuclear metallohydrolases such as the metallo-ß-lactamases to enhance our understanding of hydrolytic cleavage of important substrates like phosphoesters and c-lactams. Overall, this project has led to a better understanding of the metal ion binding and active site structural features of the enzyme GpdQ. Daumann describes how she successfully immobilized phosphoesterase and related biomimetics on solid supports for potential applications in the area of bioremediation of organophosphate pesticides. Analysis shows that both the enzyme and biomimetics can be stored on the solid support without loss of activity. Furthermore, the author specroscopically and mechanistically characterized a number of Zn(II), Cd(II) and Co(II) complexes, some of which are among the most active biomimetics towards organophosphates reported to date. This thesis makes excellent reading for non-specialists because each chapter includes a short introduction section
Member of
Cataloging source
GW5XE
http://library.link/vocab/creatorName
Daumann, Lena Josefine
Dewey number
572/.7
Illustrations
illustrations
Index
no index present
LC call number
QP601
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
Springer theses,
http://library.link/vocab/subjectName
  • Enzymes
  • Enzymology
  • Biomimetics
  • SCIENCE
  • Biomimetics
  • Enzymes
  • Enzymology
  • Chemistry
  • Biochemical Engineering
  • Enzymology
  • Spectroscopy/Spectrometry
Label
Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes, Lena Josefine Daumann
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-319-06629-5
Instantiates
Publication
Note
"Doctoral thesis accepted by University of Queensland, Australia."
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
From the Contents: Introduction -- Experimental -- Understanding the Overall Structure of GpdQ and Metal Binding -- Structural and Mechanistic Studies of Zn(II) Complexes as Phosphoesterase Models
Dimensions
unknown
Extent
1 online resource (xxi, 239 pages)
File format
unknown
Form of item
online
Isbn
9783319066288
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
c
Note
SpringerLink
Other control number
10.1007/978-3-319-06629-5
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)881229434
  • (OCoLC)ocn881229434
Label
Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes, Lena Josefine Daumann
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-319-06629-5
Publication
Note
"Doctoral thesis accepted by University of Queensland, Australia."
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
From the Contents: Introduction -- Experimental -- Understanding the Overall Structure of GpdQ and Metal Binding -- Structural and Mechanistic Studies of Zn(II) Complexes as Phosphoesterase Models
Dimensions
unknown
Extent
1 online resource (xxi, 239 pages)
File format
unknown
Form of item
online
Isbn
9783319066288
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
c
Note
SpringerLink
Other control number
10.1007/978-3-319-06629-5
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)881229434
  • (OCoLC)ocn881229434

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