The Resource Selected Topics in Mass Spectrometry in the Biomolecular Sciences, edited by Richard M. Caprioli, Antonio Malorni, Giovanni Sindona, (electronic resource)

Selected Topics in Mass Spectrometry in the Biomolecular Sciences, edited by Richard M. Caprioli, Antonio Malorni, Giovanni Sindona, (electronic resource)

Label
Selected Topics in Mass Spectrometry in the Biomolecular Sciences
Title
Selected Topics in Mass Spectrometry in the Biomolecular Sciences
Statement of responsibility
edited by Richard M. Caprioli, Antonio Malorni, Giovanni Sindona
Title variation
Proceedings of the NATO Advanced Study Institute on Mass Spectrometry in the Biomolecular Sciences, Altavilla-Milicia (PA), Italy, 7-18 July 1996
Creator
Contributor
Subject
Genre
Language
eng
Summary
Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Environmental applications are also included, with examples of some specific cases. <br/> Fundamentals and applications are treated with the same degree of depth: the first two parts of the book therefore provide a basis for the understanding of the biomolecular applications section. <br/> <em>Audience:</em> Ideal for advanced graduate students of chemistry who have learned some basic mass spectrometry. Also useful for Ph. D. students in chemistry, biology and medicine. Of value to researchers in academic and industrial laboratories
Member of
Cataloging source
I9W
http://library.link/vocab/creatorName
Caprioli, R. M
Dewey number
543
Index
no index present
LC call number
QP519.9.M3
Literary form
non fiction
Nature of contents
encyclopedias
http://library.link/vocab/relatedWorkOrContributorName
  • Malorni, Antonio
  • Sindona, Giovanni
Series statement
NATO ASI Series, Series C: Mathematical and Physical Sciences, 1389-2185
Series volume
504
http://library.link/vocab/subjectName
  • Mass spectrometry
  • Biomolecules
  • Biomolecules
  • Mass spectrometry
Label
Selected Topics in Mass Spectrometry in the Biomolecular Sciences, edited by Richard M. Caprioli, Antonio Malorni, Giovanni Sindona, (electronic resource)
Link
http://dx.doi.org/10.1007/978-94-011-5165-8
Instantiates
Publication
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
I: Methods in Mass Spectrometry -- Electrospray Ionization: Theory and Application -- Atmospheric Pressure Ionization (ESI and APCI) Theory and Application -- Matrix-Assisted Laser Desorpition-Ionization (MALDI) Mass Spectrometry: Principles and Applications -- High Sensitivity ESI/MS and MALDI MS -- Optimised GC/MS Interfacing Systems and Operating Conditions -- Quantitative Analysis by Mass Spectrometry: Some Important Considerations -- Optimization of Mass Spectrometric Ionisation Efficiency Data -- Role of Internal Energy in Mass Spectrometric Fragmentation -- Interaction of Metal Ions and Protons with Simple Biomolecules. Structure Information from Bond Energies and Entropy Effects -- A Promising Marriage Between Theory and Experiment: Density Functional Method Versus Mass Spectrometry -- II: Instrumentation for Mass Analysis and Detection -- Recent Advances in Magnet Sector Mass Spectrometry -- Quadrupole Mass Filters and Quadrupole Ion Traps -- Time-of-Flight Mass Spectrometry -- Combined Analyzer Technologies -- Fourier Transform Mass Spectrometry -- III: Application to Biomolecules -- Protein Characterization by MS in Pharmaceutical Industry. Structural Characterization of Modified Forms of Recombinant Hirudin Sequence Variant 1 and Direct Batch Analysis -- Folding Pathways of Disulphide Containing Proteins -- Integration of Chemical Modification Reactions and Mass Spectrometric Methods in Protein Characterisation -- PSD-MALDI Analysis of Peptides -- Development of a Mass Spectrometric Approach for the Characterisation of Hemoglobin Adducts -- Reactivity of Antineoplastic Drugs with Model Peptides Studied by Advanced Mass Spectrometry Methodologies -- Applications of Mass Spectrometry in Biochemical Studies of Nucleosides, Nucleotides and Nucleic Acids -- MALDI Mass Analysis of Oligonucleotides -- DNA Adducts in Human Carcinogenesis. Clues to Etiology and Mechanism -- MALDI MS of Oligo and Polysaccharides -- Mass Spectrometry of Isoeicosanoids as Novel Lipid Substances -- The Role of Mass Spectrometry in the Characterization of Plant Metabolites from Crude Extracts -- Environmental Applications of Mass Spectrometry: Toxaphene Analysis -- The Determination of Polar Compounds in the Aquatic Environment -- Some Mass Spectrometry Contributions in the Study of Cultural Heritage
Dimensions
unknown
Extent
1 online resource (612 pages).
Form of item
online
Isbn
9789401151658
Isbn Type
(electronic bk.)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-94-011-5165-8
Specific material designation
remote
System control number
  • (OCoLC)840311138
  • (OCoLC)ocn840311138
Label
Selected Topics in Mass Spectrometry in the Biomolecular Sciences, edited by Richard M. Caprioli, Antonio Malorni, Giovanni Sindona, (electronic resource)
Link
http://dx.doi.org/10.1007/978-94-011-5165-8
Publication
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
I: Methods in Mass Spectrometry -- Electrospray Ionization: Theory and Application -- Atmospheric Pressure Ionization (ESI and APCI) Theory and Application -- Matrix-Assisted Laser Desorpition-Ionization (MALDI) Mass Spectrometry: Principles and Applications -- High Sensitivity ESI/MS and MALDI MS -- Optimised GC/MS Interfacing Systems and Operating Conditions -- Quantitative Analysis by Mass Spectrometry: Some Important Considerations -- Optimization of Mass Spectrometric Ionisation Efficiency Data -- Role of Internal Energy in Mass Spectrometric Fragmentation -- Interaction of Metal Ions and Protons with Simple Biomolecules. Structure Information from Bond Energies and Entropy Effects -- A Promising Marriage Between Theory and Experiment: Density Functional Method Versus Mass Spectrometry -- II: Instrumentation for Mass Analysis and Detection -- Recent Advances in Magnet Sector Mass Spectrometry -- Quadrupole Mass Filters and Quadrupole Ion Traps -- Time-of-Flight Mass Spectrometry -- Combined Analyzer Technologies -- Fourier Transform Mass Spectrometry -- III: Application to Biomolecules -- Protein Characterization by MS in Pharmaceutical Industry. Structural Characterization of Modified Forms of Recombinant Hirudin Sequence Variant 1 and Direct Batch Analysis -- Folding Pathways of Disulphide Containing Proteins -- Integration of Chemical Modification Reactions and Mass Spectrometric Methods in Protein Characterisation -- PSD-MALDI Analysis of Peptides -- Development of a Mass Spectrometric Approach for the Characterisation of Hemoglobin Adducts -- Reactivity of Antineoplastic Drugs with Model Peptides Studied by Advanced Mass Spectrometry Methodologies -- Applications of Mass Spectrometry in Biochemical Studies of Nucleosides, Nucleotides and Nucleic Acids -- MALDI Mass Analysis of Oligonucleotides -- DNA Adducts in Human Carcinogenesis. Clues to Etiology and Mechanism -- MALDI MS of Oligo and Polysaccharides -- Mass Spectrometry of Isoeicosanoids as Novel Lipid Substances -- The Role of Mass Spectrometry in the Characterization of Plant Metabolites from Crude Extracts -- Environmental Applications of Mass Spectrometry: Toxaphene Analysis -- The Determination of Polar Compounds in the Aquatic Environment -- Some Mass Spectrometry Contributions in the Study of Cultural Heritage
Dimensions
unknown
Extent
1 online resource (612 pages).
Form of item
online
Isbn
9789401151658
Isbn Type
(electronic bk.)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-94-011-5165-8
Specific material designation
remote
System control number
  • (OCoLC)840311138
  • (OCoLC)ocn840311138

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