The Resource Reverse transcriptase inhibitors in HIV/AIDS therapy, edited by Gail Skowron, Richard Ogden ; foreword by Joep M.A. Lange, (electronic resource)

Reverse transcriptase inhibitors in HIV/AIDS therapy, edited by Gail Skowron, Richard Ogden ; foreword by Joep M.A. Lange, (electronic resource)

Label
Reverse transcriptase inhibitors in HIV/AIDS therapy
Title
Reverse transcriptase inhibitors in HIV/AIDS therapy
Statement of responsibility
edited by Gail Skowron, Richard Ogden ; foreword by Joep M.A. Lange
Contributor
Subject
Genre
Language
eng
Summary
Despite significant pharmacological advances, the backbone of the most highly active antiretroviral therapy regimens for controlling HIV/AIDS is still a combination of reverse transcriptase inhibitors (RTIs) first discovered in the late 1980s. In Reverse Transcriptase Inhibitors in HIV/AIDS Therapy, leading experts in AIDS/HIV drug discovery and development review all aspects of RTIs (nucleosides, nucleotides, and non-nucleosides), including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history, and thoroughly discuss the question of toxicity and resistance to this class of drugs. They also address three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment in general, and on vertical transmission in the developing world. Highlights include a thorough discussion of side effects, resistance, and treatment in the third world. Comprehensive and up-to-date, Reverse Transcriptase Inhibitors in HIIV/AIDS Therapy offers a magisterial survey of the discovery, clinical development, current use, and future possibilities of all drugs that treat HIV/AIDS by inhibiting the viral reverse transcriptase
Member of
Is part of
Cataloging source
COO
Dewey number
616.97/92061
Illustrations
illustrations
Index
index present
LC call number
RC606.7
LC item number
.R48 2006
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2006 G-977
  • WC 503.2
NLM item number
R452 2006
http://library.link/vocab/relatedWorkOrContributorDate
1953-
http://library.link/vocab/relatedWorkOrContributorName
  • Skowron, Gail
  • Ogden, Richard C.
Series statement
Infectious disease
http://library.link/vocab/subjectName
  • AIDS (Disease)
  • HIV infections
  • Reverse transcriptase
  • Antiretroviral agents
  • Acquired Immunodeficiency Syndrome
  • HIV Infections
  • Reverse Transcriptase Inhibitors
  • Médicaments contre le sida
  • Infections à VIH
  • Transcriptase inverse
  • Antirétroviraux
  • MEDICAL
  • HEALTH & FITNESS
  • Medicine & Public Health
  • Infectious Diseases
  • Reverse transcriptase
  • Antiretroviral agents
  • Acquired Immunodeficiency Syndrome
  • HIV Infections
  • Reverse Transcriptase Inhibitors
  • Electronic books
  • AIDS (Disease)
  • HIV infections
Label
Reverse transcriptase inhibitors in HIV/AIDS therapy, edited by Gail Skowron, Richard Ogden ; foreword by Joep M.A. Lange, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59745-085-0
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Structural studies on HIV reverse transcriptase related to drug discovery / David K. Stammers and Jingshan Ren -- Zidovudine, lamivudine, and abacavir / Monica Carten and Harold Kessler -- Stavudine, didanosine, and zalcitabine / Gail Skowron, Sapna Chowdhry and Michael R. Stevens -- Emtricitabine / Gail Skowron, Jeffrey Bratberg and Rudi Pauwels -- Nucleotide analogs / Craig J. Hoesley -- Resistance to nucleoside and nucleotide reverse transcriptase inhibitors / Nancy Shulman and Mark Winters -- Pharmacokinetics of reverse transcriptase inhibitors / Patrick Hoggard [and others] -- Peripheral neuropathy associated with nucleoside reverse transcriptase inhibitor therapy / Bruce A. Cohen and Russell Bartt -- Mitochondrial dysfunction and nucleoside reverse transcriptase inhibitor therapy: a pathophysiological perspective / William Lewis -- Mitochondrial toxicity and lipodystrophy / Grace McComsey -- Nevirapine / David Asmuth and Richard Pollard -- Efavirenz / Graeme J. Moyle and Brian Conway -- Delavirdine / Brian Conway -- Resistance to non-nucleoside reverse transcriptase inhibitors / F. Ramzi Asfour and Richard Haubrich -- Vertical transmission of HIV and therapeutic interventions / Susan Cu-Uvin, Arlene Bardeguez and Carla Chibwesha -- New reverse transcriptase inhibitors in development / Rudi Pauwels -- Antiretroviral drugs for millions / Allan Ronald, Ellie Katabira and Merle Sande
Dimensions
unknown
Extent
1 online resource (xiii, 527 pages)
Form of item
online
Isbn
9781597450850
Isbn Type
(e-ISBN)
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
9786610832156
Other physical details
illustrations.
Specific material designation
remote
Stock number
83215
System control number
  • (OCoLC)174134757
  • (OCoLC)ocn174134757
Label
Reverse transcriptase inhibitors in HIV/AIDS therapy, edited by Gail Skowron, Richard Ogden ; foreword by Joep M.A. Lange, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59745-085-0
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Structural studies on HIV reverse transcriptase related to drug discovery / David K. Stammers and Jingshan Ren -- Zidovudine, lamivudine, and abacavir / Monica Carten and Harold Kessler -- Stavudine, didanosine, and zalcitabine / Gail Skowron, Sapna Chowdhry and Michael R. Stevens -- Emtricitabine / Gail Skowron, Jeffrey Bratberg and Rudi Pauwels -- Nucleotide analogs / Craig J. Hoesley -- Resistance to nucleoside and nucleotide reverse transcriptase inhibitors / Nancy Shulman and Mark Winters -- Pharmacokinetics of reverse transcriptase inhibitors / Patrick Hoggard [and others] -- Peripheral neuropathy associated with nucleoside reverse transcriptase inhibitor therapy / Bruce A. Cohen and Russell Bartt -- Mitochondrial dysfunction and nucleoside reverse transcriptase inhibitor therapy: a pathophysiological perspective / William Lewis -- Mitochondrial toxicity and lipodystrophy / Grace McComsey -- Nevirapine / David Asmuth and Richard Pollard -- Efavirenz / Graeme J. Moyle and Brian Conway -- Delavirdine / Brian Conway -- Resistance to non-nucleoside reverse transcriptase inhibitors / F. Ramzi Asfour and Richard Haubrich -- Vertical transmission of HIV and therapeutic interventions / Susan Cu-Uvin, Arlene Bardeguez and Carla Chibwesha -- New reverse transcriptase inhibitors in development / Rudi Pauwels -- Antiretroviral drugs for millions / Allan Ronald, Ellie Katabira and Merle Sande
Dimensions
unknown
Extent
1 online resource (xiii, 527 pages)
Form of item
online
Isbn
9781597450850
Isbn Type
(e-ISBN)
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
9786610832156
Other physical details
illustrations.
Specific material designation
remote
Stock number
83215
System control number
  • (OCoLC)174134757
  • (OCoLC)ocn174134757

Library Locations

  • Architecture LibraryBorrow it
    Gould Hall 830 Van Vleet Oval Rm. 105, Norman, OK, 73019, US
    35.205706 -97.445050
  • Bizzell Memorial LibraryBorrow it
    401 W. Brooks St., Norman, OK, 73019, US
    35.207487 -97.447906
  • Boorstin CollectionBorrow it
    401 W. Brooks St., Norman, OK, 73019, US
    35.207487 -97.447906
  • Chinese Literature Translation ArchiveBorrow it
    401 W. Brooks St., RM 414, Norman, OK, 73019, US
    35.207487 -97.447906
  • Engineering LibraryBorrow it
    Felgar Hall 865 Asp Avenue, Rm. 222, Norman, OK, 73019, US
    35.205706 -97.445050
  • Fine Arts LibraryBorrow it
    Catlett Music Center 500 West Boyd Street, Rm. 20, Norman, OK, 73019, US
    35.210371 -97.448244
  • Harry W. Bass Business History CollectionBorrow it
    401 W. Brooks St., Rm. 521NW, Norman, OK, 73019, US
    35.207487 -97.447906
  • History of Science CollectionsBorrow it
    401 W. Brooks St., Rm. 521NW, Norman, OK, 73019, US
    35.207487 -97.447906
  • John and Mary Nichols Rare Books and Special CollectionsBorrow it
    401 W. Brooks St., Rm. 509NW, Norman, OK, 73019, US
    35.207487 -97.447906
  • Library Service CenterBorrow it
    2601 Technology Place, Norman, OK, 73019, US
    35.185561 -97.398361
  • Price College Digital LibraryBorrow it
    Adams Hall 102 307 West Brooks St., Norman, OK, 73019, US
    35.210371 -97.448244
  • Western History CollectionsBorrow it
    Monnet Hall 630 Parrington Oval, Rm. 300, Norman, OK, 73019, US
    35.209584 -97.445414
Processing Feedback ...