The Resource RNA interference : from biology to clinical applications, edited by Wei-Ping Min, Thomas Ichim, (electronic resource)

RNA interference : from biology to clinical applications, edited by Wei-Ping Min, Thomas Ichim, (electronic resource)

Label
RNA interference : from biology to clinical applications
Title
RNA interference
Title remainder
from biology to clinical applications
Statement of responsibility
edited by Wei-Ping Min, Thomas Ichim
Contributor
Subject
Genre
Language
eng
Summary
From the early days when RNA interference was a strange artifact in worms to the 2006 Noble Prize received by Fire and Mello and the current clinical trials, the field of RNA interference has grown at a breakneck pace. In RNA Interference: From Biology to Clinical Applications, expert contributors provide an overview of the most current science and protocols that span the biological disciplines from detailed nucleic acid chemistry, to pharmacology, to the manipulation of signal transduction pathways. Divided into three distinct sections, this volume delves into the physiology of RNA interference, RNA interference in the laboratory and siRNA delivery, and preclinical and clinical issues associated with the use of RNAi-inducing agents as drugs in order to stimulate new questions and offer the tools necessary to start addressing those questions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and inspiring, RNA Interference: From Biology to Clinical Applications aims to promote and motivate innovation by reviewing what has been done, providing details of how it has been done, and encouraging speculation on what the future may hold
Member of
Cataloging source
GW5XE
Dewey number
612.015
Illustrations
illustrations
Index
index present
LC call number
QH450.25
LC item number
.R63 2010
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • handbooks
NLM call number
QU 58.7
http://library.link/vocab/relatedWorkOrContributorDate
1976-
http://library.link/vocab/relatedWorkOrContributorName
  • Min, Wei-Ping
  • Ichim, Thomas
Series statement
  • Methods in molecular biology,
  • Springer protocols
Series volume
623
http://library.link/vocab/subjectName
  • RNA editing
  • Gene silencing
  • RNA Interference
  • Gene Silencing
  • Biomedicine
  • Laboratory Medicine
  • Gene silencing
  • RNA editing
Label
RNA interference : from biology to clinical applications, edited by Wei-Ping Min, Thomas Ichim, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-60761-588-0
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Endogenous antiviral mechanisms of RNA interference : a comparative biology perspective / Abubaker M.E. Sidahmed and Bruce Wilkie -- Monitoring innate immune recruitment by siRNAs in mammalian cells / Michael P. Gantier and Bryan R.G. Williams -- Current knowledge of microRNAs and noncoding RNAs in virus-infected cells / Dominique L. Ouellet and Patrick Provost -- Allele-specific silencing by RNA interference / Hirohiko Hohjoh -- Computational siRNA design considering alternative splicing / Young J. Kim -- Bioinformatic approaches to siRNA selection and optimization / Pirkko Muhonen and Harry Holthofer -- Optimized gene silencing by co-expression of mulitple shRNAs in a single vector / Yasuhito Ishigaki, Akihiro Nagao, and Tsukasa Matsunaga -- Strategies in designing multigene expression units to downregulate HIV-1 / Jane Zhang and John J. Rossi -- Designing optimal siRNA based on target site accessibility / Ivo L. Hofacker and Hakim Tafer -- Chemical synthesis of 2'-O-alkylated siRNAs / Joachim W. Engels ... [et al.] -- siRNA specific delivery system for targeting dendritic cells / Xiufen Zheng ... [et al.] -- Hydrodynamic delivery protocols / Piotr G. Rychahou and B. Mark Evers -- New methods for reverse transfection with siRNA from a solid surface / Satoshi Fujita ... [et al.] -- Nonviral siRNA delivery for gene silencing in neurodegenerative diseases / Satya Prakash, Meenakshi Malhotra, and Venkatesh Rengaswamy
  • Using siRNA to uncover novel oncogenic signaling pathways / Jin-Mei Lai, Chi-Ying F. Huang, and Chang-Han Chen -- Biodegradable polymer-mediated sh/siRNA delivery for cancer studies / Dhananjay J. Jere and Chong-Su Cho -- Cellular siRNA delivery using TatU1A and photo-induced RNA interference / Tamaki Endoh and Takashi Ohtsuki -- Polyethylenimine (PEI)/siRNA-mediated gene knockdown in vitro and in vivo / Sabrina Höbel and Achim Aigner -- Transfection of siRNAs in multiple myeloma cell lines / Jose L.R. Brito, Nicola Brown, and Garth J. Morgan -- A new approach for therapeutic use by RNA interference in the brain / Yukio Akaneya -- Inhibitory RNA molecules in immunotherapy for cancer / Chih-Ping Mao and T.-C. Wu -- Preventing tissue injury using siRNA / Zhu-Xu Zhang ... [et al.] -- Preventing immune rejection through gene silencing / Xusheng Zhang, Mu Li, and Wei-Ping Min -- Topical application of siRNA targeting cutaneous dendritic cells in allergic skin disease / Miyuki Azuma, Patcharee Ritprajak, and Masaaki Hashiguchi -- Direct application of siRNA for in vivo pain research / Philippe Sarret, Louis Doré-Savard, and Nicolas Beaudet -- A potential therapeutic for pandemic influenza using RNA interference / Shaguna Seth ... [et al.] -- Evaluation of targets for ovarian cancer gene silencing therapy : in vitro and in vivo approaches / Anastasia Malek and Oleg Tchernitsa
Dimensions
unknown
Extent
1 online resource (xvi, 450 p.)
Form of item
online
Isbn
9781607615880
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-60761-588-0
Other physical details
ill.
Specific material designation
remote
Stock number
978-1-60761-587-3
System control number
  • (OCoLC)658898997
  • (OCoLC)ocn658898997
Label
RNA interference : from biology to clinical applications, edited by Wei-Ping Min, Thomas Ichim, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-60761-588-0
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Endogenous antiviral mechanisms of RNA interference : a comparative biology perspective / Abubaker M.E. Sidahmed and Bruce Wilkie -- Monitoring innate immune recruitment by siRNAs in mammalian cells / Michael P. Gantier and Bryan R.G. Williams -- Current knowledge of microRNAs and noncoding RNAs in virus-infected cells / Dominique L. Ouellet and Patrick Provost -- Allele-specific silencing by RNA interference / Hirohiko Hohjoh -- Computational siRNA design considering alternative splicing / Young J. Kim -- Bioinformatic approaches to siRNA selection and optimization / Pirkko Muhonen and Harry Holthofer -- Optimized gene silencing by co-expression of mulitple shRNAs in a single vector / Yasuhito Ishigaki, Akihiro Nagao, and Tsukasa Matsunaga -- Strategies in designing multigene expression units to downregulate HIV-1 / Jane Zhang and John J. Rossi -- Designing optimal siRNA based on target site accessibility / Ivo L. Hofacker and Hakim Tafer -- Chemical synthesis of 2'-O-alkylated siRNAs / Joachim W. Engels ... [et al.] -- siRNA specific delivery system for targeting dendritic cells / Xiufen Zheng ... [et al.] -- Hydrodynamic delivery protocols / Piotr G. Rychahou and B. Mark Evers -- New methods for reverse transfection with siRNA from a solid surface / Satoshi Fujita ... [et al.] -- Nonviral siRNA delivery for gene silencing in neurodegenerative diseases / Satya Prakash, Meenakshi Malhotra, and Venkatesh Rengaswamy
  • Using siRNA to uncover novel oncogenic signaling pathways / Jin-Mei Lai, Chi-Ying F. Huang, and Chang-Han Chen -- Biodegradable polymer-mediated sh/siRNA delivery for cancer studies / Dhananjay J. Jere and Chong-Su Cho -- Cellular siRNA delivery using TatU1A and photo-induced RNA interference / Tamaki Endoh and Takashi Ohtsuki -- Polyethylenimine (PEI)/siRNA-mediated gene knockdown in vitro and in vivo / Sabrina Höbel and Achim Aigner -- Transfection of siRNAs in multiple myeloma cell lines / Jose L.R. Brito, Nicola Brown, and Garth J. Morgan -- A new approach for therapeutic use by RNA interference in the brain / Yukio Akaneya -- Inhibitory RNA molecules in immunotherapy for cancer / Chih-Ping Mao and T.-C. Wu -- Preventing tissue injury using siRNA / Zhu-Xu Zhang ... [et al.] -- Preventing immune rejection through gene silencing / Xusheng Zhang, Mu Li, and Wei-Ping Min -- Topical application of siRNA targeting cutaneous dendritic cells in allergic skin disease / Miyuki Azuma, Patcharee Ritprajak, and Masaaki Hashiguchi -- Direct application of siRNA for in vivo pain research / Philippe Sarret, Louis Doré-Savard, and Nicolas Beaudet -- A potential therapeutic for pandemic influenza using RNA interference / Shaguna Seth ... [et al.] -- Evaluation of targets for ovarian cancer gene silencing therapy : in vitro and in vivo approaches / Anastasia Malek and Oleg Tchernitsa
Dimensions
unknown
Extent
1 online resource (xvi, 450 p.)
Form of item
online
Isbn
9781607615880
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-60761-588-0
Other physical details
ill.
Specific material designation
remote
Stock number
978-1-60761-587-3
System control number
  • (OCoLC)658898997
  • (OCoLC)ocn658898997

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