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The Resource Quantitative trait loci : methods and protocols, edited by Nicola J. Camp and Angela Cox, (electronic resource)

Quantitative trait loci : methods and protocols, edited by Nicola J. Camp and Angela Cox, (electronic resource)

Label
Quantitative trait loci : methods and protocols
Title
Quantitative trait loci
Title remainder
methods and protocols
Statement of responsibility
edited by Nicola J. Camp and Angela Cox
Contributor
Subject
Genre
Language
eng
Summary
Statistical methods for the analysis of quantitative trait locus (QTL), in conjunction with genome-wide screening technologies, are today yielding exciting results in the study of human disease, experimental organisms, and agriculture. In Quantitative Trait Loci: Methods and Protocols, Drs. Nicola Camp and Angela Cox have assembled a highly experienced panel of statistical geneticists who demonstrate in a step-by-step fashion how to use this powerful methodology and associated software for the detection and fine mapping of quantitative trait loci. Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and useful variations and/or extensions to standard methods are included that ease the reader toward understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov chain Monte Carlo method for joint linkage and segregation analysis. Up-to-date and highly practical, Quantitative Trait Loci: Methods and Protocols makes available to nonmathematical investigators a step-by-step guide to the productive use today of all the latest techniques for localizing genes involved in complex quantitative traits
Member of
Cataloging source
COO
Dewey number
576.5/07/27
Illustrations
illustrations
Index
index present
LC call number
QH438.4.S73
LC item number
Q36 2002
Literary form
non fiction
NAL call number
QH506
NAL item number
.M45 v. 195
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QH 445.2
NLM item number
  • ME9616J v.195 2002
  • Q1 2002
Series statement
Methods in molecular biology
Series volume
v. 195
Label
Quantitative trait loci : methods and protocols, edited by Nicola J. Camp and Angela Cox, (electronic resource)
Link
http://dx.doi.org/10.1385/1592591760
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
pt. 1. Mapping quantitative trait loci in humans -- Association studies / Jennifer H. Barrett -- Parametric linkage analysis / Lyle J. Palmer -- Nonparametric linkage analysis: I. Haseman-Elston / Chad P. Garner -- Nonparametric linkage analysis: II. Variance components / Angela J. Marlow -- Linkage and association: the transmission/disequilibrium test for QTLs / Mark M. Iles -- Joint linkage and segregation analysis using Markov chain Monte Carlo methods / Ellen M. Wijsman -- pt. 2. Mapping quantitative trait loci in rodents -- Approaches to the analysis of QTL data in mice, using the nonobese diabetic mouse as an example / Heather J. Cordell -- Experimental designs for QTL fine mapping in rodents / Anne Shalom -- Approaches to the analysis of complex quantitative phenotypes and marker map construction based on the analysis of rat models of hypertension / Dominique Gauguier -- A case study of QTL analysis in a mouse model of asthma / Youming Zhang -- pt. 3. Mapping quantitative trait loci in agricultural settings -- QTL analysis in plants / Shizhong Xu -- QTL analysis in livestock / Joao L. Rocha
Dimensions
unknown
Extent
1 online resource (xii, 359 pages)
Form of item
online
Isbn
9781592591763
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote
System control number
  • (OCoLC)171134533
  • (OCoLC)ocn171134533
Label
Quantitative trait loci : methods and protocols, edited by Nicola J. Camp and Angela Cox, (electronic resource)
Link
http://dx.doi.org/10.1385/1592591760
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
pt. 1. Mapping quantitative trait loci in humans -- Association studies / Jennifer H. Barrett -- Parametric linkage analysis / Lyle J. Palmer -- Nonparametric linkage analysis: I. Haseman-Elston / Chad P. Garner -- Nonparametric linkage analysis: II. Variance components / Angela J. Marlow -- Linkage and association: the transmission/disequilibrium test for QTLs / Mark M. Iles -- Joint linkage and segregation analysis using Markov chain Monte Carlo methods / Ellen M. Wijsman -- pt. 2. Mapping quantitative trait loci in rodents -- Approaches to the analysis of QTL data in mice, using the nonobese diabetic mouse as an example / Heather J. Cordell -- Experimental designs for QTL fine mapping in rodents / Anne Shalom -- Approaches to the analysis of complex quantitative phenotypes and marker map construction based on the analysis of rat models of hypertension / Dominique Gauguier -- A case study of QTL analysis in a mouse model of asthma / Youming Zhang -- pt. 3. Mapping quantitative trait loci in agricultural settings -- QTL analysis in plants / Shizhong Xu -- QTL analysis in livestock / Joao L. Rocha
Dimensions
unknown
Extent
1 online resource (xii, 359 pages)
Form of item
online
Isbn
9781592591763
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote
System control number
  • (OCoLC)171134533
  • (OCoLC)ocn171134533

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