The Resource Pathogen genomics : impact on human health, edited by Karen Joy Shaw, (electronic resource)

Pathogen genomics : impact on human health, edited by Karen Joy Shaw, (electronic resource)

Label
Pathogen genomics : impact on human health
Title
Pathogen genomics
Title remainder
impact on human health
Statement of responsibility
edited by Karen Joy Shaw
Contributor
Subject
Genre
Language
eng
Summary
Genome sequencing and analysis have yielded a rich harvest of fundamental information about pathogenesis and have raised significant new possibilities for effective therapeutic intervention. In Pathogen Genomics: Impact on Human Health, a panel of leading infectious disease researchers and pharmaceutical scientists comprehensively review the latest genomic technologies and their application to infectious disease prevention, diagnosis, and treatment. The authors' cross-disciplinary approach-with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa-reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools. The authors also discuss the application of DNA microarrays and the impact of genome sequencing comparisons to the discovery and choices of novel drug targets. The result is a better understanding of how these tools can be used to explore the fundamentals of microbial pathogenesis, as well as how pathogens interact with each other and with their host environments. Broad-ranging and illuminating, Pathogen Genomics: Impact on Human Health offers today's infectious disease specialists an authoritative analysis of the new genomic technologies and their productive application to drug discovery, vaccine development, and diagnostics
Member of
Action
digitized
Cataloging source
N$T
Dewey number
579/.165
Illustrations
illustrations
Index
index present
LC call number
QH434
LC item number
.P384 2002eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QH 307.2
NLM item number
P297 2002
http://library.link/vocab/relatedWorkOrContributorName
Shaw, Karen Joy
Series statement
Infectious disease
http://library.link/vocab/subjectName
  • Microbial genetics
  • Gene expression
  • Fungal gene expression
  • DNA microarrays
  • Pathogenic microorganisms
  • Genomics
  • Microbiological Phenomena
  • Genomics
  • Génétique microbienne
  • Expression génique
  • Champignons
  • Puces à ADN
  • Micro-organismes pathogènes
  • Génomique
  • SCIENCE
  • SCIENCE
  • DNA microarrays
  • Fungal gene expression
  • Gene expression
  • Genomics
  • Microbial genetics
  • Pathogenic microorganisms
  • Genética microbiana
  • Microbiologia (genética;patologia)
  • Doenças infecciosas (microbiologia)
  • Protozoa
Label
Pathogen genomics : impact on human health, edited by Karen Joy Shaw, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-172-5
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
I Viruses -- 1 Antiviral Drug Target Discovery with DNA Microarrays -- 2 Chipping Away at HIV Pathogenesis -- 3 Microarray Analysis of Human Papillomavirus Pathogenesis -- 4 Ribozymes as Gene Therapeutic Agents for HIV/AIDS: A Potential Paradigm Shift -- II Bacteria -- 5 Genomics and New Technologies Applied to Antibacterial Drug Discovery -- 6 Genomics of the Mycobacterium tuberculosis Complex and BCG Vaccines -- 7 Bacterial 'Genes-to-Screens' in the Post-Genomic Era -- 8 DNA Microarray Expression Analysis in Antibacterial Drug Discovery -- 9 The Influence of Genomics on the Molecular Epidemiology of Nosocomial Pathogens -- 10 Borrelia Genomics as a Tool for Studying Pathogenesis and Vaccine Development -- III Fungi -- 11 Antifungal Target Discovery and Evaluation: Lessons from Saccharomyces cerevisiae -- 12 Antifungal Drug Discovery: Old Drugs, New Tools -- 13 Cryptococcus neoformans: A Molecular Model for the Study of Fungal Pathogenesis and Drug Discovery in the Genomic Era -- 14 Antifungal Target Selection in Aspergillus nidulans: Using Bioinformatics to Make the Difference -- 15 Functional Genomics of Histoplasma capsulatum: Dimorphism and Virulence -- 16 Gene Finding in Coccidioides immitis: Searching for Immunogenic Proteins -- IV Protozoa -- 17 Toxoplasma gondii: A Model for Evolutionary Genomics and Chemotherapy -- 18 The Molecular Biology and Pathogenicity of Entamoeba histolytica
Dimensions
unknown
Extent
1 online resource (xv, 309 pages)
Form of item
online
Isbn
9781468496833
Isbn Type
(print)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-172-5
Other physical details
illustrations (some color).
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
  • (OCoLC)52467525
  • (OCoLC)ocm52467525
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Label
Pathogen genomics : impact on human health, edited by Karen Joy Shaw, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-172-5
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
I Viruses -- 1 Antiviral Drug Target Discovery with DNA Microarrays -- 2 Chipping Away at HIV Pathogenesis -- 3 Microarray Analysis of Human Papillomavirus Pathogenesis -- 4 Ribozymes as Gene Therapeutic Agents for HIV/AIDS: A Potential Paradigm Shift -- II Bacteria -- 5 Genomics and New Technologies Applied to Antibacterial Drug Discovery -- 6 Genomics of the Mycobacterium tuberculosis Complex and BCG Vaccines -- 7 Bacterial 'Genes-to-Screens' in the Post-Genomic Era -- 8 DNA Microarray Expression Analysis in Antibacterial Drug Discovery -- 9 The Influence of Genomics on the Molecular Epidemiology of Nosocomial Pathogens -- 10 Borrelia Genomics as a Tool for Studying Pathogenesis and Vaccine Development -- III Fungi -- 11 Antifungal Target Discovery and Evaluation: Lessons from Saccharomyces cerevisiae -- 12 Antifungal Drug Discovery: Old Drugs, New Tools -- 13 Cryptococcus neoformans: A Molecular Model for the Study of Fungal Pathogenesis and Drug Discovery in the Genomic Era -- 14 Antifungal Target Selection in Aspergillus nidulans: Using Bioinformatics to Make the Difference -- 15 Functional Genomics of Histoplasma capsulatum: Dimorphism and Virulence -- 16 Gene Finding in Coccidioides immitis: Searching for Immunogenic Proteins -- IV Protozoa -- 17 Toxoplasma gondii: A Model for Evolutionary Genomics and Chemotherapy -- 18 The Molecular Biology and Pathogenicity of Entamoeba histolytica
Dimensions
unknown
Extent
1 online resource (xv, 309 pages)
Form of item
online
Isbn
9781468496833
Isbn Type
(print)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-172-5
Other physical details
illustrations (some color).
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
  • (OCoLC)52467525
  • (OCoLC)ocm52467525
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

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