The Resource P53 in the clinics, Pierre Hainaut, Magali Olivier, Klas G. Wiman, editors, (electronic resource)

P53 in the clinics, Pierre Hainaut, Magali Olivier, Klas G. Wiman, editors, (electronic resource)

Label
P53 in the clinics
Title
P53 in the clinics
Statement of responsibility
Pierre Hainaut, Magali Olivier, Klas G. Wiman, editors
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
With over 60,000 referenced publications, p53 has emerged as one of the most important factors in human cancer. Research on p53 has led to a complete overhaul of our understanding of the molecular basis of human cancer. In recent years, these major advances in knowledge are starting to impact on cancer management and therapy. This book thus captures a critical turning point in p53 research, from basic to translational research and clinical application. p53 in the Clinics follows the success of 25 Years of p53 Research and condensates in a series of authoritative chapters the considerable progress on the applications of p53 into the clinics and the substantial advances on diseases caused by inheritance of p53 defects, on somatic p53 mutations as biomarkers in molecular pathology, on progress in gene therapy and on developments of innovative drugs and clinical trials. This volume will appeal to a wide audience of students and professionals in basic and clinical cancer research and treatment, and will highlight the exciting “next steps” in p53 research and applications
Cataloging source
MiAaPQ
Dewey number
616.994042
Illustrations
illustrations
Index
index present
Language note
English
LC call number
RC268.44.P16
LC item number
P53 2012
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Hainaut, Pierre
  • Olivier, Magali
  • Wiman, Klas
http://library.link/vocab/subjectName
  • p53 antioncogene
  • p53 protein
Label
P53 in the clinics, Pierre Hainaut, Magali Olivier, Klas G. Wiman, editors, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
Foreword -- p53 activities and the hallmarks of cancer -- The inheritance of p53 -- p53: Guardian of the metabolome -- The p53 family and stem cell biology -- Mutant p53-driven tumorigenesis -- Humanized p53 mouse models -- p53 models for mammary carcinogenesis -- TP53 somatic mutations: Prognostic and predictive value in human cancers -- Assessing TP53 status in human tumors - lessons from breast cancer -- TP53 germline mutations: Genetics of Li-Fraumeni Syndrome -- TP53 gene therapy -- Upstream targets in the p53 pathway -- p53-reactivating molecules as research tools and anti-cancer drugs -- Restoring mutant p53 activity -- p53-immunotherapy of cancer -- Designing p53 trials: a surgical oncologist view -- p53 in the clinic: a pathologist view -- p53 in genetic counseling -- Index
Dimensions
unknown
Extent
1 online resource (356 p.)
Form of item
online
Isbn
9786613935007
Media category
computer
Media type code
  • c
Other control number
10.1007/978-1-4614-3676-8
Specific material designation
remote
System control number
  • (CKB)2670000000245971
  • (EBL)994554
  • (OCoLC)809370153
  • (SSID)ssj0000738672
  • (PQKBManifestationID)11378516
  • (PQKBTitleCode)TC0000738672
  • (PQKBWorkID)10670905
  • (PQKB)10607737
  • (DE-He213)978-1-4614-3676-8
  • (MiAaPQ)EBC994554
  • (EXLCZ)992670000000245971
Label
P53 in the clinics, Pierre Hainaut, Magali Olivier, Klas G. Wiman, editors, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
Foreword -- p53 activities and the hallmarks of cancer -- The inheritance of p53 -- p53: Guardian of the metabolome -- The p53 family and stem cell biology -- Mutant p53-driven tumorigenesis -- Humanized p53 mouse models -- p53 models for mammary carcinogenesis -- TP53 somatic mutations: Prognostic and predictive value in human cancers -- Assessing TP53 status in human tumors - lessons from breast cancer -- TP53 germline mutations: Genetics of Li-Fraumeni Syndrome -- TP53 gene therapy -- Upstream targets in the p53 pathway -- p53-reactivating molecules as research tools and anti-cancer drugs -- Restoring mutant p53 activity -- p53-immunotherapy of cancer -- Designing p53 trials: a surgical oncologist view -- p53 in the clinic: a pathologist view -- p53 in genetic counseling -- Index
Dimensions
unknown
Extent
1 online resource (356 p.)
Form of item
online
Isbn
9786613935007
Media category
computer
Media type code
  • c
Other control number
10.1007/978-1-4614-3676-8
Specific material designation
remote
System control number
  • (CKB)2670000000245971
  • (EBL)994554
  • (OCoLC)809370153
  • (SSID)ssj0000738672
  • (PQKBManifestationID)11378516
  • (PQKBTitleCode)TC0000738672
  • (PQKBWorkID)10670905
  • (PQKB)10607737
  • (DE-He213)978-1-4614-3676-8
  • (MiAaPQ)EBC994554
  • (EXLCZ)992670000000245971

Library Locations

  • Architecture LibraryBorrow it
    Gould Hall 830 Van Vleet Oval Rm. 105, Norman, OK, 73019, US
    35.205706 -97.445050
  • Bizzell Memorial LibraryBorrow it
    401 W. Brooks St., Norman, OK, 73019, US
    35.207487 -97.447906
  • Boorstin CollectionBorrow it
    401 W. Brooks St., Norman, OK, 73019, US
    35.207487 -97.447906
  • Chinese Literature Translation ArchiveBorrow it
    401 W. Brooks St., RM 414, Norman, OK, 73019, US
    35.207487 -97.447906
  • Engineering LibraryBorrow it
    Felgar Hall 865 Asp Avenue, Rm. 222, Norman, OK, 73019, US
    35.205706 -97.445050
  • Fine Arts LibraryBorrow it
    Catlett Music Center 500 West Boyd Street, Rm. 20, Norman, OK, 73019, US
    35.210371 -97.448244
  • Harry W. Bass Business History CollectionBorrow it
    401 W. Brooks St., Rm. 521NW, Norman, OK, 73019, US
    35.207487 -97.447906
  • History of Science CollectionsBorrow it
    401 W. Brooks St., Rm. 521NW, Norman, OK, 73019, US
    35.207487 -97.447906
  • John and Mary Nichols Rare Books and Special CollectionsBorrow it
    401 W. Brooks St., Rm. 509NW, Norman, OK, 73019, US
    35.207487 -97.447906
  • Library Service CenterBorrow it
    2601 Technology Place, Norman, OK, 73019, US
    35.185561 -97.398361
  • Price College Digital LibraryBorrow it
    Adams Hall 102 307 West Brooks St., Norman, OK, 73019, US
    35.210371 -97.448244
  • Western History CollectionsBorrow it
    Monnet Hall 630 Parrington Oval, Rm. 300, Norman, OK, 73019, US
    35.209584 -97.445414
Processing Feedback ...