The Resource Optimized response-adaptive clinical trials : sequential treatment allocation based on Markov decision problems, Thomas Ondra

Optimized response-adaptive clinical trials : sequential treatment allocation based on Markov decision problems, Thomas Ondra

Label
Optimized response-adaptive clinical trials : sequential treatment allocation based on Markov decision problems
Title
Optimized response-adaptive clinical trials
Title remainder
sequential treatment allocation based on Markov decision problems
Statement of responsibility
Thomas Ondra
Creator
Author
Subject
Genre
Language
  • eng
  • eng
  • ger
  • eng
  • eng
Summary
Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences. Contents Introduction to Markov Decision Problems and Examples Finite and Infinite Horizon Markov Decision Problems Solution Algorithms: Backward Induction, Value Iteration and Policy Iteration Designing Response Adaptive Clinical Trials with Markov Decision Problems Target Groups Researchers and students in the fields of mathematics and statistics Professionals in the pharmaceutical industry The Author Thomas Ondra obtained his Master of Science degree in mathematics at University of Vienna. He is a research assistant and PhD student at the Section for Medical Statistics of Medical University of Vienna
Member of
Cataloging source
N$T
http://library.link/vocab/creatorName
On, Thomas
Dewey number
  • 610.72/4
  • 510
Illustrations
illustrations
Index
no index present
Language note
Abstract in German and English
LC call number
R853.S7
LC item number
O5 2015eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
BestMasters
http://library.link/vocab/subjectName
  • Clinical trials
  • Markov processes
  • MATHEMATICS
  • MATHEMATICS
  • MATHEMATICS
  • Clinical trials
  • Markov processes
Label
Optimized response-adaptive clinical trials : sequential treatment allocation based on Markov decision problems, Thomas Ondra
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-658-08344-1
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction to Markov Decision Problems and Examples -- Finite and Infinite Horizon Markov Decision Problems -- Solution Algorithms: Backward Induction, Value Iteration and Policy Iteration -- Designing Response Adaptive Clinical Trials with Markov Decision Problems
Dimensions
unknown
Extent
1 online resource (xv, 102 pages)
File format
unknown
Form of item
online
Isbn
9783658083441
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-3-658-08344-1
Other physical details
illustrations.
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)897810267
  • (OCoLC)ocn897810267
Label
Optimized response-adaptive clinical trials : sequential treatment allocation based on Markov decision problems, Thomas Ondra
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-658-08344-1
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction to Markov Decision Problems and Examples -- Finite and Infinite Horizon Markov Decision Problems -- Solution Algorithms: Backward Induction, Value Iteration and Policy Iteration -- Designing Response Adaptive Clinical Trials with Markov Decision Problems
Dimensions
unknown
Extent
1 online resource (xv, 102 pages)
File format
unknown
Form of item
online
Isbn
9783658083441
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-3-658-08344-1
Other physical details
illustrations.
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)897810267
  • (OCoLC)ocn897810267

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