The Resource Melanoma : biologically targeted therapeutics, edited by Ernest C. Borden, (electronic resource)

Melanoma : biologically targeted therapeutics, edited by Ernest C. Borden, (electronic resource)

Label
Melanoma : biologically targeted therapeutics
Title
Melanoma
Title remainder
biologically targeted therapeutics
Statement of responsibility
edited by Ernest C. Borden
Contributor
Subject
Genre
Language
eng
Summary
Substantial progress in the effective prevention and treatment of primary and recurrent melanomas is now being regularly achieved using therapeutic proteins and cells. In Melanoma: Biologically Targeted Therapeutics, Ernest C. Borden, MD, has assembled a multidisciplinary team of established and emerging leaders to detail the clinical problems and factors influencing the therapeutic deployment of these biologicals. Throughout, the focus is on providing the rationale and background by which the many promising biologically targeted therapies are translated via clinical trials into effective new therapies. Among the interventional agents treated are cytokines, monoclonal antibodies, targeted inhibitors, cellular therapies, and angiogenesis inhibitors. Special attention is given to adjuvant therapies for melanoma in patients staged as being at high risk for recurrence. These therapies include interferons, vaccines aimed at stimulating T cell response, and therapies targeted at abnormal melanoma cell proliferative signaling and angiogenesis inhibitors. Among the cutting-edge therapies discussed are novel cytokines that influence dendritic NK and T cell function, an allogenic cellular extract vaccine, and new targets (NF-kB and IL-8) for antiangiogenesis therapies. State-of-the-art and forward looking, Melanoma: Biologically Targeted Therapeutics critically evaluates the biological, cellular, and targeted therapies that are already reducing mortality from primary melanomas, and are expected increasingly to continue so for the foreseeable future
Member of
Action
digitized
Cataloging source
N$T
Dewey number
616.99/47706
Illustrations
illustrations
Index
index present
LC call number
RC280.M37
LC item number
M446 2002eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QZ 200
NLM item number
M51785 2002
http://library.link/vocab/relatedWorkOrContributorName
Borden, Ernest
Series statement
Current clinical oncology
http://library.link/vocab/subjectName
  • Melanoma
  • Biological products
  • Proteins
  • Melanoma
  • Biological Therapy
  • Genetic Therapy
  • MEDICAL
  • HEALTH & FITNESS
  • Melanom
  • Therapie
  • Biological products -- Therapeutic use
  • Electronic books. -- local
  • Melanoma -- Immunotherapy
  • Proteins -- Therapeutic use
Label
Melanoma : biologically targeted therapeutics, edited by Ernest C. Borden, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-159-6
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
I Perspective on the Clinical Disease -- 1 Management of Primary Malignant Melanoma -- 2 A Pathologist's Perspective on Prognostic Featuresof Malignant Melanoma -- 3 Clinical Prognostic Factors and Staging -- II Biological and Targeted Therapeutics -- 4 Principles of Antitumor Immunity and Tumor-Mediated Immunosuppression -- 5 Immunotherapy of Advanced Melanoma Directed at Specific Antigens -- 6 Melanoma Antigens: Vaccines and Monoclonal Antibodies -- 7 Interleukin-2 -- 8 Interleukin-12: Immunologic and Antitumor Effects in Human Malignant Melanoma -- 9 Interferons: Preclinical and Clinical Studies in Melanoma -- 10 Biochemotherapy of Melanoma -- 11 Signal Transduction Abnormalities as Therapeutic Targets -- 12 Tumor Angiogenesis -- 13 Antiangiogenic Therapy for Melanoma
Dimensions
unknown
Extent
1 online resource (xvi, 389 pages)
Form of item
online
Isbn
9781468496680
Isbn Type
(print)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-159-6
Other physical details
illustrations.
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
  • (OCoLC)52467366
  • (OCoLC)ocm52467366
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Label
Melanoma : biologically targeted therapeutics, edited by Ernest C. Borden, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-159-6
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
I Perspective on the Clinical Disease -- 1 Management of Primary Malignant Melanoma -- 2 A Pathologist's Perspective on Prognostic Featuresof Malignant Melanoma -- 3 Clinical Prognostic Factors and Staging -- II Biological and Targeted Therapeutics -- 4 Principles of Antitumor Immunity and Tumor-Mediated Immunosuppression -- 5 Immunotherapy of Advanced Melanoma Directed at Specific Antigens -- 6 Melanoma Antigens: Vaccines and Monoclonal Antibodies -- 7 Interleukin-2 -- 8 Interleukin-12: Immunologic and Antitumor Effects in Human Malignant Melanoma -- 9 Interferons: Preclinical and Clinical Studies in Melanoma -- 10 Biochemotherapy of Melanoma -- 11 Signal Transduction Abnormalities as Therapeutic Targets -- 12 Tumor Angiogenesis -- 13 Antiangiogenic Therapy for Melanoma
Dimensions
unknown
Extent
1 online resource (xvi, 389 pages)
Form of item
online
Isbn
9781468496680
Isbn Type
(print)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-159-6
Other physical details
illustrations.
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
  • (OCoLC)52467366
  • (OCoLC)ocm52467366
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

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