The Resource Mechanisms of gene regulation, Carsten Carlberg, Ferdinand Molnár

Mechanisms of gene regulation, Carsten Carlberg, Ferdinand Molnár

Label
Mechanisms of gene regulation
Title
Mechanisms of gene regulation
Statement of responsibility
Carsten Carlberg, Ferdinand Molnár
Creator
Contributor
Author
Subject
Genre
Language
eng
Summary
This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule stating that "a picture tells more than thousand words". The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors, chromatin and non-coding RNA, respectively. Besides its value as a textbook, Mechanisms of Gene Regulation will be a useful reference for individuals working in biomedical laboratories
Cataloging source
GW5XE
http://library.link/vocab/creatorName
Carlberg, Carsten
Dewey number
572.8/65
Illustrations
illustrations
Index
no index present
LC call number
QH450
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU 475
http://library.link/vocab/relatedWorkOrContributorName
Molnár, Ferdinand
http://library.link/vocab/subjectName
  • Genetic regulation
  • Genetic regulation
  • Biomedicine
  • Gene Expression
  • Protein Structure
  • Gene Expression Regulation
Label
Mechanisms of gene regulation, Carsten Carlberg, Ferdinand Molnár
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-94-017-7741-4
Instantiates
Publication
Antecedent source
file reproduced from an electronic resource
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
black and white
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Overview: What is gene expression? -- The impact of chromatin -- The basal transcriptional machinery -- Transcription factors -- Linking signal transduction and gene regulation -- Switching genes on and off at the example of nuclear receptors -- Mapping the genome -- Chromatin modifiers -- Genomic imprinting -- The epigenome -- Chromatin remodeling -- Chromatin architecture -- Regulatory RNA
Dimensions
unknown
Edition
Second edition.
Extent
1 online resource (xv, 210 pages)
File format
one file format
Form of item
online
Isbn
9789401777407
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-94-017-7741-4
Other physical details
illustrations (some color)
Quality assurance targets
unknown
Reformatting quality
unknown
Specific material designation
remote
System control number
  • (OCoLC)951775533
  • (OCoLC)ocn951775533
Label
Mechanisms of gene regulation, Carsten Carlberg, Ferdinand Molnár
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-94-017-7741-4
Publication
Antecedent source
file reproduced from an electronic resource
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
black and white
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Overview: What is gene expression? -- The impact of chromatin -- The basal transcriptional machinery -- Transcription factors -- Linking signal transduction and gene regulation -- Switching genes on and off at the example of nuclear receptors -- Mapping the genome -- Chromatin modifiers -- Genomic imprinting -- The epigenome -- Chromatin remodeling -- Chromatin architecture -- Regulatory RNA
Dimensions
unknown
Edition
Second edition.
Extent
1 online resource (xv, 210 pages)
File format
one file format
Form of item
online
Isbn
9789401777407
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-94-017-7741-4
Other physical details
illustrations (some color)
Quality assurance targets
unknown
Reformatting quality
unknown
Specific material designation
remote
System control number
  • (OCoLC)951775533
  • (OCoLC)ocn951775533

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