The Resource Mathematical Modelling of the Cell Cycle Stress Response, by Elahe Radmaneshfar, (electronic resource)

Mathematical Modelling of the Cell Cycle Stress Response, by Elahe Radmaneshfar, (electronic resource)

Label
Mathematical Modelling of the Cell Cycle Stress Response
Title
Mathematical Modelling of the Cell Cycle Stress Response
Statement of responsibility
by Elahe Radmaneshfar
Creator
Author
Author
Subject
Language
  • eng
  • eng
Summary
The cell cycle is a sequence of biochemical events that are controlled by complex but robust molecular machinery. This enables cells to achieve accurate self-reproduction under a broad range of conditions. Environmental changes are transmitted by molecular signaling networks, which coordinate their actions with the cell cycle. This work presents the first description of two complementary computational models describing the influence of osmotic stress on the entire cell cycle of S. cerevisiae. Our models condense a vast amount of experimental evidence on the interaction of the cell cycle network components with the osmotic stress pathway. Importantly, it is only by considering the entire cell cycle that we are able to make a series of novel predictions which emerge from the coupling between the molecular components of different cell cycle phases. The model-based predictions are supported by experiments in S. cerevisiae and, moreover, have recently been observed in other eukaryotes. Furthermore our models reveal the mechanisms that emerge as a result of the interaction between the cell cycle and stress response networks
Member of
http://library.link/vocab/creatorName
Radmaneshfar, Elahe
Dewey number
570.285
Dissertation note
Thesis (Ph. D.) -- University of Aberdeen, UK, 2013.
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsaut
ccjJCZXF5cw
Language note
English
LC call number
QH505
Literary form
non fiction
Nature of contents
dictionaries
Series statement
  • Springer theses
  • Springer Theses, Recognizing Outstanding Ph.D. Research,
http://library.link/vocab/subjectName
  • Cell cycle
  • Physiology
  • Bioinformatics
  • Biological and Medical Physics, Biophysics
  • Cell Cycle Analysis
  • Physiological, Cellular and Medical Topics
  • Computational Biology/Bioinformatics
  • Applications of Graph Theory and Complex Networks
Label
Mathematical Modelling of the Cell Cycle Stress Response, by Elahe Radmaneshfar, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
A biological overview of the cell cycle and its response to osmotic stress and the α-factor -- ODE model of the cell cycle response to osmotic stress -- Boolean model of the cell cycle response to stress -- Conclusion -- List of equations, parameters and initial conditions -- Effect of methods of update on existence of fixed points
Dimensions
unknown
Edition
1st ed. 2014.
Extent
1 online resource (122 p.)
Form of item
online
Isbn
9783319007441
Media category
computer
Media type code
  • c
Other control number
10.1007/978-3-319-00744-1
Specific material designation
remote
System control number
  • (CKB)3710000000025633
  • (EBL)1538882
  • (SSID)ssj0001049527
  • (PQKBManifestationID)11592866
  • (PQKBTitleCode)TC0001049527
  • (PQKBWorkID)11019465
  • (PQKB)10749410
  • (MiAaPQ)EBC1538882
  • (DE-He213)978-3-319-00744-1
  • (EXLCZ)993710000000025633
Label
Mathematical Modelling of the Cell Cycle Stress Response, by Elahe Radmaneshfar, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
A biological overview of the cell cycle and its response to osmotic stress and the α-factor -- ODE model of the cell cycle response to osmotic stress -- Boolean model of the cell cycle response to stress -- Conclusion -- List of equations, parameters and initial conditions -- Effect of methods of update on existence of fixed points
Dimensions
unknown
Edition
1st ed. 2014.
Extent
1 online resource (122 p.)
Form of item
online
Isbn
9783319007441
Media category
computer
Media type code
  • c
Other control number
10.1007/978-3-319-00744-1
Specific material designation
remote
System control number
  • (CKB)3710000000025633
  • (EBL)1538882
  • (SSID)ssj0001049527
  • (PQKBManifestationID)11592866
  • (PQKBTitleCode)TC0001049527
  • (PQKBWorkID)11019465
  • (PQKB)10749410
  • (MiAaPQ)EBC1538882
  • (DE-He213)978-3-319-00744-1
  • (EXLCZ)993710000000025633

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