The Resource Immuno Systems Biology : A macroscopic approach for immune cell signaling, by Kumar Selvarajoo, (electronic resource)

Immuno Systems Biology : A macroscopic approach for immune cell signaling, by Kumar Selvarajoo, (electronic resource)

Label
Immuno Systems Biology : A macroscopic approach for immune cell signaling
Title
Immuno Systems Biology
Title remainder
A macroscopic approach for immune cell signaling
Statement of responsibility
by Kumar Selvarajoo
Creator
Author
Author
Subject
Language
  • eng
  • eng
Summary
Technological advances of modern biology have generated high volumes of ‘omics’ data. The natural precedence has been to put the complex information together, so that it will lead to spectacular scientific discoveries and medical breakthroughs. In this light, tremendous efforts worldwide are reshaping biological research by integrating with information science. Despite the ‘systems biology’ efforts, for major illnesses, such as proinflammatory diseases and cancer, there is clear clinical evidence that even the most current therapies, at best, control transient response and subdue to the robust adaptability of the disease state. Hence, there is a need for system-levels understanding of bio-complexity. Kumar Selvarajoo brings attention to fundamental questions governing sophisticated behaviors of the mammalian immune system. To tackle some of the complex issues, the book introduces perturbation-response approach, using the law of physics (mass flow conservation), as a means to interpret the dynamic response of major proinflammatory pathways of the immune and cancer cells. Overall, the book provides an illustrated journey that explains biological cell signaling in simple terms
Member of
http://library.link/vocab/creatorName
Selvarajoo, Kumar
Dewey number
571.96
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsaut
KZ0WTEfYC_g
Language note
English
LC call number
R-RZ
Literary form
non fiction
Nature of contents
dictionaries
Series statement
Systems Biology,
Series volume
3
http://library.link/vocab/subjectName
  • Medicine
  • Systems biology
  • Bioinformatics
  • Immunology
  • Cell biology
  • Biomedicine, general
  • Systems Biology
  • Bioinformatics
  • Computational Biology/Bioinformatics
  • Immunology
  • Cell Biology
Label
Immuno Systems Biology : A macroscopic approach for immune cell signaling, by Kumar Selvarajoo, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
Preface -- Systems biology of population cell response -- Perturbation-response approach for biological network analysis -- Basics of the mammalian immune system -- Inferring novel features of the TLR4 pathways -- Signaling Flux Redistribution -- Investigating the TLR3 signaling dynamics -- Understanding TNFR1 signaling dynamics -- TRAIL signaling in cancer -- Stochasticity and variability: insights from single cell dynamics -- Investigating single cell stochasticity in TRAIL signaling -- The distinction between single cell and population dynamics -- Finding chaos in biology -- Concluding remarks -- Index
Dimensions
unknown
Edition
1st ed. 2013.
Extent
1 online resource (152 p.)
Form of item
online
Isbn
9781461476917
Media category
computer
Media type code
  • c
Other control number
10.1007/978-1-4614-7690-0
Specific material designation
remote
System control number
  • (CKB)3710000000019027
  • (EBL)1466416
  • (SSID)ssj0001004904
  • (PQKBManifestationID)11992352
  • (PQKBTitleCode)TC0001004904
  • (PQKBWorkID)11047696
  • (PQKB)10238802
  • (DE-He213)978-1-4614-7690-0
  • (MiAaPQ)EBC1466416
  • (EXLCZ)993710000000019027
Label
Immuno Systems Biology : A macroscopic approach for immune cell signaling, by Kumar Selvarajoo, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
Preface -- Systems biology of population cell response -- Perturbation-response approach for biological network analysis -- Basics of the mammalian immune system -- Inferring novel features of the TLR4 pathways -- Signaling Flux Redistribution -- Investigating the TLR3 signaling dynamics -- Understanding TNFR1 signaling dynamics -- TRAIL signaling in cancer -- Stochasticity and variability: insights from single cell dynamics -- Investigating single cell stochasticity in TRAIL signaling -- The distinction between single cell and population dynamics -- Finding chaos in biology -- Concluding remarks -- Index
Dimensions
unknown
Edition
1st ed. 2013.
Extent
1 online resource (152 p.)
Form of item
online
Isbn
9781461476917
Media category
computer
Media type code
  • c
Other control number
10.1007/978-1-4614-7690-0
Specific material designation
remote
System control number
  • (CKB)3710000000019027
  • (EBL)1466416
  • (SSID)ssj0001004904
  • (PQKBManifestationID)11992352
  • (PQKBTitleCode)TC0001004904
  • (PQKBWorkID)11047696
  • (PQKB)10238802
  • (DE-He213)978-1-4614-7690-0
  • (MiAaPQ)EBC1466416
  • (EXLCZ)993710000000019027

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