The Resource Galactose Regulon of Yeast : From Genetics to Systems Biology, by Paike Jayadeva Bhat, (electronic resource)

Galactose Regulon of Yeast : From Genetics to Systems Biology, by Paike Jayadeva Bhat, (electronic resource)

Label
Galactose Regulon of Yeast : From Genetics to Systems Biology
Title
Galactose Regulon of Yeast
Title remainder
From Genetics to Systems Biology
Statement of responsibility
by Paike Jayadeva Bhat
Creator
Author
Author
Subject
Language
  • eng
  • eng
Summary
The galactose regulon of yeast is one of the best studied regulons. It is an ideal paradigm for demonstrating fundamental and evolving concepts in biology and is used in this book as a model system to explain various facets of conventional and modern biology. The book starts with a brief historical overview on yeast research, i.e. early observations in enzyme adaptation, classical genetics, formulating hypotheses based on genetic inference. This is followed by molecular genetics of the galactose regulon, isolation of genes and testing of the hypotheses. The power of mutational analysis in deciphering molecular mechanisms is conveyed. Further, contemporary topics such as genomics, evolution, single cell analysis of transcriptional switching, binary and graded responses, biological consequences of feed back regulation in genetic circuits, and stochasticity are addressed
http://library.link/vocab/creatorName
Bhat, Paike Jayadeva
Dewey number
  • 572.8/29563
  • 572.829562
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsaut
m0nMWctu47c
Language note
English
LC call number
QR1-502
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/subjectName
  • Microbiology
  • Microbial genetics
  • Microbial genomics
  • Cytology
  • Biochemistry
  • Biotechnology
  • Microbiology
  • Microbial Genetics and Genomics
  • Cell Biology
  • Biochemistry, general
  • Biotechnology
Label
Galactose Regulon of Yeast : From Genetics to Systems Biology, by Paike Jayadeva Bhat, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Introduction. An overview. Yeast is a eukaryotic model organism. A cell as a biochemical entity -- Adaptation to Environment. Growth and multiplication. Enzyme adaptation. Induction to Leloir enzymes -- Genetic Dissection of Galactose Metabolism. Genetic analysis of GAL regulon. Genetic mapping of GAL genes -- Genetic Analysis GAL Genetic Switch. Negative control by the repressor. Operator repressor model of GAL regulon. Genetic interactions. Conditional lethal mutations. Revised model of GAL genetic switch. Signal transduction in GAL regulon -- Molecular Genetics of GAL Regulon. Cloning: a perspective. Genomic organization of GAL cluster. Isolation of GAL4: the transcriptional activator. Isolation of GAL80: the repressor. Isolation of GAL3: the signal transducer -- Signal Transduction Revisited. Revised model of signal transduction. Genetic dissection of signal transduction -- Versatile Galactose Genetic Switch. Transcription activation. Glucose repression. Fine regulation of GAL genetic switch -- Paradigmatic Role of Galactose Switch. GAL regulon and genomics. GAL regulon and systems biology. Galactose metabolism and evolution. GAL Switch as a tool. Lessons learned
Dimensions
unknown
Extent
1 online resource (231 p.)
Form of item
online
Isbn
9786611241865
Media category
computer
Media type code
c
Other control number
10.1007/978-3-540-74015-5
Specific material designation
remote
System control number
  • (CKB)1000000000401072
  • (EBL)371896
  • (OCoLC)227011533
  • (SSID)ssj0000160478
  • (PQKBManifestationID)11159346
  • (PQKBTitleCode)TC0000160478
  • (PQKBWorkID)10182325
  • (PQKB)10341665
  • (DE-He213)978-3-540-74015-5
  • (MiAaPQ)EBC371896
  • (EXLCZ)991000000000401072
Label
Galactose Regulon of Yeast : From Genetics to Systems Biology, by Paike Jayadeva Bhat, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Introduction. An overview. Yeast is a eukaryotic model organism. A cell as a biochemical entity -- Adaptation to Environment. Growth and multiplication. Enzyme adaptation. Induction to Leloir enzymes -- Genetic Dissection of Galactose Metabolism. Genetic analysis of GAL regulon. Genetic mapping of GAL genes -- Genetic Analysis GAL Genetic Switch. Negative control by the repressor. Operator repressor model of GAL regulon. Genetic interactions. Conditional lethal mutations. Revised model of GAL genetic switch. Signal transduction in GAL regulon -- Molecular Genetics of GAL Regulon. Cloning: a perspective. Genomic organization of GAL cluster. Isolation of GAL4: the transcriptional activator. Isolation of GAL80: the repressor. Isolation of GAL3: the signal transducer -- Signal Transduction Revisited. Revised model of signal transduction. Genetic dissection of signal transduction -- Versatile Galactose Genetic Switch. Transcription activation. Glucose repression. Fine regulation of GAL genetic switch -- Paradigmatic Role of Galactose Switch. GAL regulon and genomics. GAL regulon and systems biology. Galactose metabolism and evolution. GAL Switch as a tool. Lessons learned
Dimensions
unknown
Extent
1 online resource (231 p.)
Form of item
online
Isbn
9786611241865
Media category
computer
Media type code
c
Other control number
10.1007/978-3-540-74015-5
Specific material designation
remote
System control number
  • (CKB)1000000000401072
  • (EBL)371896
  • (OCoLC)227011533
  • (SSID)ssj0000160478
  • (PQKBManifestationID)11159346
  • (PQKBTitleCode)TC0000160478
  • (PQKBWorkID)10182325
  • (PQKB)10341665
  • (DE-He213)978-3-540-74015-5
  • (MiAaPQ)EBC371896
  • (EXLCZ)991000000000401072

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