The Resource Evaluating Clinical Research : All that glitters is not gold, by Bengt D. Furberg, Curt D. Furberg, (electronic resource)

Evaluating Clinical Research : All that glitters is not gold, by Bengt D. Furberg, Curt D. Furberg, (electronic resource)

Label
Evaluating Clinical Research : All that glitters is not gold
Title
Evaluating Clinical Research
Title remainder
All that glitters is not gold
Statement of responsibility
by Bengt D. Furberg, Curt D. Furberg
Creator
Contributor
Author
Author
Subject
Language
  • eng
  • eng
Summary
The objective of this book is to make its readers better informed and more critical consumers of clinical research to help them recognize the strengths and the weaknesses of scientific publications. In doing so, the reader will be able to distinguish patient-important and methodologically sound studies from those having limitations in design, conduct and interpretation. There are no prerequisites for reading this book. The text is basic and has no statistical formulas. Key take-home messages are listed at the end of each chapter. The large number of cartoons has two purposes: First, to make the text easier to read and generate a few laughs and, second, to underscore specific points, sometimes in a provocative way. Bengt D. Furberg, MD, PhD is board-certified in internal medicine. After spending a decade as medical director in the pharmaceutical industry, he now serves as medical consultant, evaluating the safety and efficacy of pharmaceutical products and medical devices and promoting evidence-based medicine. His brother, Curt D. Furberg, MD, PhD, is Professor in the Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA. After arriving in the United States from Sweden, he worked at the National Heart, Lung, and Blood Institute of the National Institutes of Health for 12 years. He is co-author of Fundamentals of Clinical Trials with Lawrence M. Friedman and David L. DeMets. His areas of interest are clinical trials, evidence-based medicine and drug safety. The authors have acquired much of their knowledge about clinical studies through the "trial and error" method. Thus, they have personal experience with many of the problems they describe
http://library.link/vocab/creatorName
Furberg, Bengt D
Dewey number
  • 610.72
  • 616.0072
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsaut
  • G7olhT-YOPA
  • iSGt4WSVFSU
Language note
English
LC call number
QA276-280
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Furberg, Curt D.
http://library.link/vocab/subjectName
  • Statistics
  • Quality of Life
  • Toxicology
  • Statistics for Life Sciences, Medicine, Health Sciences
  • Quality of Life Research
  • Pharmacology/Toxicology
Label
Evaluating Clinical Research : All that glitters is not gold, by Bengt D. Furberg, Curt D. Furberg, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references (p. 149-158) and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
What is the purpose of this book? -- Why is benefit-to-harm balance essential to treatment decisions? -- What are the strengths of randomized controlled clinical trials? -- What are the weaknesses of randomized controlled clinical trials? -- Do meta-analyses provide the ultimate truth? -- What are the strengths of observational studies? -- What are the weaknesses of observational studies? -- Were the scientific questions stated in advance? -- Were the treatment groups comparable initially? -- Why is blinding/masking so important? -- How is symptomatic improvement measured? -- Is it really possible to assess quality of life? -- What is the value of biologic markers in drug evaluation? -- How are adverse drug reactions measured? -- How representative are study subjects in clinical trials? -- What happened to the study subjects who disappeared from the analysis? -- How reliable are active-control trials? -- How informative are composite outcomes? -- Do changes in biologic markers predict clinical benefit? -- How trustworthy are the authors? -- Does publication in a reputable scientific journal guarantee quality? -- Is it necessary to be a biostatistician to interpret scientific data? -- Are all drugs of a class interchangeable? -- How much confidence can be placed on economic analysis? -- How should I handle the massive flow of information? -- How well is research translated into clinical care?
Dimensions
unknown
Edition
2nd ed.
Extent
1 online resource (167 p.)
Form of item
online
Isbn
9781281138538
Media category
computer
Media type code
c
Other control number
10.1007/978-0-387-72899-5
Specific material designation
remote
System control number
  • (CKB)1000000000407828
  • (EBL)336651
  • (OCoLC)232115357
  • (SSID)ssj0000150721
  • (PQKBManifestationID)11167304
  • (PQKBTitleCode)TC0000150721
  • (PQKBWorkID)10281168
  • (PQKB)10987485
  • (DE-He213)978-0-387-72899-5
  • (MiAaPQ)EBC336651
  • (EXLCZ)991000000000407828
Label
Evaluating Clinical Research : All that glitters is not gold, by Bengt D. Furberg, Curt D. Furberg, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references (p. 149-158) and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
What is the purpose of this book? -- Why is benefit-to-harm balance essential to treatment decisions? -- What are the strengths of randomized controlled clinical trials? -- What are the weaknesses of randomized controlled clinical trials? -- Do meta-analyses provide the ultimate truth? -- What are the strengths of observational studies? -- What are the weaknesses of observational studies? -- Were the scientific questions stated in advance? -- Were the treatment groups comparable initially? -- Why is blinding/masking so important? -- How is symptomatic improvement measured? -- Is it really possible to assess quality of life? -- What is the value of biologic markers in drug evaluation? -- How are adverse drug reactions measured? -- How representative are study subjects in clinical trials? -- What happened to the study subjects who disappeared from the analysis? -- How reliable are active-control trials? -- How informative are composite outcomes? -- Do changes in biologic markers predict clinical benefit? -- How trustworthy are the authors? -- Does publication in a reputable scientific journal guarantee quality? -- Is it necessary to be a biostatistician to interpret scientific data? -- Are all drugs of a class interchangeable? -- How much confidence can be placed on economic analysis? -- How should I handle the massive flow of information? -- How well is research translated into clinical care?
Dimensions
unknown
Edition
2nd ed.
Extent
1 online resource (167 p.)
Form of item
online
Isbn
9781281138538
Media category
computer
Media type code
c
Other control number
10.1007/978-0-387-72899-5
Specific material designation
remote
System control number
  • (CKB)1000000000407828
  • (EBL)336651
  • (OCoLC)232115357
  • (SSID)ssj0000150721
  • (PQKBManifestationID)11167304
  • (PQKBTitleCode)TC0000150721
  • (PQKBWorkID)10281168
  • (PQKB)10987485
  • (DE-He213)978-0-387-72899-5
  • (MiAaPQ)EBC336651
  • (EXLCZ)991000000000407828

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