The Resource Entry inhibitors in HIV therapy, edited by Jacqueline D. Reeves and Cynthia A. Derdeyn, (electronic resource)

Entry inhibitors in HIV therapy, edited by Jacqueline D. Reeves and Cynthia A. Derdeyn, (electronic resource)

Label
Entry inhibitors in HIV therapy
Title
Entry inhibitors in HIV therapy
Statement of responsibility
edited by Jacqueline D. Reeves and Cynthia A. Derdeyn
Contributor
Subject
Genre
Language
eng
Summary
Entry Inhibitors in HIV Therapy presents the current status of this relatively new and highly dynamic class of inhibitors and provides a unique overview of obstacles and considerations for HIV entry inhibition compared to other antiretroviral targets. The introductory chapters of this book present an overview of entry inhibitors, review current knowledge of how Env mediates entry, and discuss the challenge of genetic diversity in this region of the viral genome. Subsequent chapters feature current information on individual classes of entry inhibitors that target each step of the virus entry pathway, from attachment to membrane fusion. There is an emphasis on the complex determinants of entry inhibitor susceptibility, resistance mechanisms, the need for clinical phenotyping, and how these issues create new challenges for antiretroviral therapy. Encouraging pre-clinical studies of entry inhibitors as microbicidesare also discussed. The final chapters highlight the current status of entry inhibitors in clinical studies, the major milestone achieved with FDA approval of enfuvirtide, and review drug development, past and present. In summary, this book presents a comprehensive and current overview of entry inhibitors from an expert panel of authors with diverse backgrounds and perspectives, incorporating many unrelenting successes against a backdrop of formidable challenges. It is of interest to basic science researchers as well as clinical physicians
Member of
Is part of
Cataloging source
COO
Dewey number
616.97/92061
Illustrations
illustrations
Index
index present
LC call number
RC606.7
LC item number
.E58 2007
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2007 H-450
  • WC 503.2
NLM item number
E61 2007
http://library.link/vocab/relatedWorkOrContributorName
  • Reeves, Jacqueline D
  • Derdeyn, Cynthia A
Series statement
Milestones in drug therapy
http://library.link/vocab/subjectName
  • HIV infections
  • HIV Infections
  • HIV Fusion Inhibitors
  • Medicine
  • MEDICAL
  • HEALTH & FITNESS
  • Biomédecine
  • Sciences de la vie
  • HIV infections
Label
Entry inhibitors in HIV therapy, edited by Jacqueline D. Reeves and Cynthia A. Derdeyn, (electronic resource)
Link
http://dx.doi.org/10.1007/978-3-7643-7783-0
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Dimensions
unknown
Extent
1 online resource (ix, 200 pages)
Form of item
online
Isbn
9783764377830
Isbn Type
(e-ISBN)
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote
Stock number
96991
System control number
  • (OCoLC)367765268
  • (OCoLC)ocn367765268
Label
Entry inhibitors in HIV therapy, edited by Jacqueline D. Reeves and Cynthia A. Derdeyn, (electronic resource)
Link
http://dx.doi.org/10.1007/978-3-7643-7783-0
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Dimensions
unknown
Extent
1 online resource (ix, 200 pages)
Form of item
online
Isbn
9783764377830
Isbn Type
(e-ISBN)
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote
Stock number
96991
System control number
  • (OCoLC)367765268
  • (OCoLC)ocn367765268

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