The Resource Design and Analysis of Vaccine Studies, by M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner, (electronic resource)

Design and Analysis of Vaccine Studies, by M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner, (electronic resource)

Label
Design and Analysis of Vaccine Studies
Title
Design and Analysis of Vaccine Studies
Statement of responsibility
by M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner
Creator
Contributor
Author
Author
Subject
Language
  • eng
  • eng
Summary
Widespread immunization has many different kinds of effects in individuals and populations, including in the unvaccinated individuals. The challenge is in understanding and estimating all of these effects. This book presents a unified conceptual framework of the different effects of vaccination at the individual and at the population level. The book covers many different vaccine effects, including vaccine efficacy for susceptibility, for disease, for post-infection outcomes, and for infectiousness. The book includes methods for evaluating indirect, total and overall effects of vaccination programs in populations. Topics include household studies, evaluating correlates of immune protection, and applications of casual inference. Material on concepts of infectious disease epidemiology, transmission models, casual inference, and vaccines provides background for the reader. This is the first book to present vaccine evaluation in this comprehensive conceptual framework. This book is intended for colleagues and students in statistics, biostatistics, epidemiology, and infectious diseases. Most essential concepts are described in simple language accessible to epidemiologists, followed by technical material accessible to statisticians. M. Elizabeth Halloran and Ira Longini are professors of biostatistics at the University of Washington and the Fred Hutchinson Cancer Research Center in Seattle. Claudio Struchiner is professor of epidemiology and biostatistics at the Brazilian School of Public Health of the Oswaldo Cruz Foundation in Rio de Janeiro. The authors are prominent researchers in the area. Halloran and Struchiner developed the study designs for dependent happenings to delineate indirect, total, and overall effects. Halloran has made contributions at the interface of epidemiological methods, causal inference, and transmission dynamics. Longini works in the area of stochastic processes applied to epidemiological infectious disease problems, specializing in the mathematical and statistical theory of epidemics. Struchiner has contributed to understanding the role of transmission in interpreting vaccine effects
Member of
Is Subseries of
http://library.link/vocab/creatorName
Halloran, M. Elizabeth
Dewey number
  • 510.1
  • 615/.372072
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsaut
  • zrVVzNUI54g
  • URUi68m3Cjc
  • 28NfuvsAOxc
Language note
English
LC call number
R858-859.7
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Longini, Jr., Ira M.
  • Struchiner, Claudio J.
Series statement
Statistics for Biology and Health,
http://library.link/vocab/subjectName
  • Medical records
  • Epidemiology
  • Emerging infectious diseases
  • Statistics
  • Health Informatics
  • Epidemiology
  • Infectious Diseases
  • Statistics for Life Sciences, Medicine, Health Sciences
Label
Design and Analysis of Vaccine Studies, by M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
and Examples -- Overview of Vaccine Effects and Study Designs -- Immunology and Early Phase Trials -- Binomial and Stochastic Transmission Models -- and Deterministic Models -- Evaluating Protective Effects of Vaccination -- Modes of Action and Time-Varying VE -- Further Evaluation of Protective Effects -- Vaccine Effects on Post-Infection Outcomes -- Household-Based Studies -- Analysis of Households in Communities -- Analysis of Independent Households -- Assessing Indirect, Total, and Overall Effects -- Randomization and Baseline Transmission -- Surrogates of Protection
Dimensions
unknown
Edition
1st ed. 2010.
Extent
1 online resource (396 p.)
Form of item
online
Isbn
9781282834989
Media category
computer
Media type code
c
Other control number
10.1007/978-0-387-68636-3
Specific material designation
remote
System control number
  • (CKB)2510000000006517
  • (EBL)510676
  • (OCoLC)663097058
  • (SSID)ssj0000322523
  • (PQKBManifestationID)11247828
  • (PQKBTitleCode)TC0000322523
  • (PQKBWorkID)10289024
  • (PQKB)10557385
  • (DE-He213)978-0-387-68636-3
  • (MiAaPQ)EBC510676
  • (EXLCZ)992510000000006517
Label
Design and Analysis of Vaccine Studies, by M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
and Examples -- Overview of Vaccine Effects and Study Designs -- Immunology and Early Phase Trials -- Binomial and Stochastic Transmission Models -- and Deterministic Models -- Evaluating Protective Effects of Vaccination -- Modes of Action and Time-Varying VE -- Further Evaluation of Protective Effects -- Vaccine Effects on Post-Infection Outcomes -- Household-Based Studies -- Analysis of Households in Communities -- Analysis of Independent Households -- Assessing Indirect, Total, and Overall Effects -- Randomization and Baseline Transmission -- Surrogates of Protection
Dimensions
unknown
Edition
1st ed. 2010.
Extent
1 online resource (396 p.)
Form of item
online
Isbn
9781282834989
Media category
computer
Media type code
c
Other control number
10.1007/978-0-387-68636-3
Specific material designation
remote
System control number
  • (CKB)2510000000006517
  • (EBL)510676
  • (OCoLC)663097058
  • (SSID)ssj0000322523
  • (PQKBManifestationID)11247828
  • (PQKBTitleCode)TC0000322523
  • (PQKBWorkID)10289024
  • (PQKB)10557385
  • (DE-He213)978-0-387-68636-3
  • (MiAaPQ)EBC510676
  • (EXLCZ)992510000000006517

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