The Resource Comparative studies between HTLV-1 and HTLV-2 function and pathobiology, topic editors Umberto Bertazzoni and Françoise Bex, (electronic resource)

Comparative studies between HTLV-1 and HTLV-2 function and pathobiology, topic editors Umberto Bertazzoni and Françoise Bex, (electronic resource)

Label
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology
Title
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology
Statement of responsibility
topic editors Umberto Bertazzoni and Françoise Bex
Contributor
Editor
Subject
Language
  • eng
  • eng
Summary
Human T-cell leukemia viruses 1 and 2 (HTLV-1 and HTLV-2) have similar genomic structure but differ in pathogenicity. HTLV-1 is associated with ATL whereas HTLV-2 has not been linked to lymphoproliferative diseases. A comparative analysis between the two viruses is important to reach a better understanding of the difference in pathogenesis. A key role is attributed to the Tax proteins; Tax-1 function and structure has been thoroughly investigated but less is known about Tax-2. Recent studies on HTLV-1 and HTLV-2 expression strategies highlighted converging patterns as well as peculiar differences in the expression of regulatory proteins that might influence the pathobiology of these viruses. The study of interaction of regulatory proteins with cellular pathways factors has opened new avenues in understanding the mechanisms of gene transcription and deregulation. However, further investigation is needed on the role on innate immunity on HTLV-1 and HTLV-2 pathogenesis. Concerning the mechanisms of infection and related diseases and of their interaction with other co-infecting agents, the comparison between HTLV-1 and HTLV-2 needs further investigation
Cataloging source
PQKB
Index
no index present
LC call number
QR201.H86
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Bertazzoni, Umberto
  • Bex, Françoise
Series statement
Frontiers research topics
http://library.link/vocab/subjectName
  • Microbiology
  • Microbiology & Immunology
  • Biology
  • Health & Biological Sciences
Target audience
specialized
Label
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology, topic editors Umberto Bertazzoni and Françoise Bex, (electronic resource)
Instantiates
Publication
Copyright
Note
Bibliographic Level Mode of Issuance: Monograph
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Dimensions
unknown
Extent
1 online resource (94 pages)
Form of item
  • electronic
  • online
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations; digital, PDF file(s).
Specific material designation
remote
System control number
  • (CKB)3710000000504559
  • (SSID)ssj0001666880
  • (PQKBManifestationID)16455795
  • (PQKBTitleCode)TC0001666880
  • (PQKBWorkID)15001023
  • (PQKB)11783531
  • (WaSeSS)IndRDA00056559
  • (EXLCZ)993710000000504559
System details
Mode of access: internet via World Wide Web
Label
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology, topic editors Umberto Bertazzoni and Françoise Bex, (electronic resource)
Publication
Copyright
Note
Bibliographic Level Mode of Issuance: Monograph
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Dimensions
unknown
Extent
1 online resource (94 pages)
Form of item
  • electronic
  • online
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations; digital, PDF file(s).
Specific material designation
remote
System control number
  • (CKB)3710000000504559
  • (SSID)ssj0001666880
  • (PQKBManifestationID)16455795
  • (PQKBTitleCode)TC0001666880
  • (PQKBWorkID)15001023
  • (PQKB)11783531
  • (WaSeSS)IndRDA00056559
  • (EXLCZ)993710000000504559
System details
Mode of access: internet via World Wide Web

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