The Resource Comparative Gene Finding : Models, Algorithms and Implementation, by Marina Axelson-Fisk, (electronic resource)

Comparative Gene Finding : Models, Algorithms and Implementation, by Marina Axelson-Fisk, (electronic resource)

Label
Comparative Gene Finding : Models, Algorithms and Implementation
Title
Comparative Gene Finding
Title remainder
Models, Algorithms and Implementation
Statement of responsibility
by Marina Axelson-Fisk
Creator
Author
Author
Subject
Language
  • eng
  • eng
Summary
Comparative genomics is an emerging field, which is being fed by an explosion in the number of possible biological sequences. This has led to an immense demand for faster, more efficient and more robust computer algorithms to analyze this large amount of data. This unique text/reference describes the state of the art in computational gene finding, with a particular focus on comparative approaches. Providing both an overview of the various methods that are applied in the field, and a concise guide on how computational gene finders are built, the book covers a broad range of topics from probability theory, statistics, information theory, optimization theory and numerical analysis. The text assumes the reader has some background in bioinformatics, especially in mathematics and mathematical statistics. A basic knowledge of analysis, probability theory and random processes would also aid the reader. Topics and features: Describes how algorithms and sequence alignments can be combined to improve the accuracy of gene finding Introduces the basic biological terms and concepts in genetics, and provides an historical overview of algorithm development Explores the gene features most commonly captured by a computational gene model, and describes the most important sub-models used Discusses the algorithms most commonly used for single-species gene finding Investigates approaches to pairwise and multiple sequence alignments Explains the basics of parameter training, covering a number of the different parameter estimation and optimization techniques commonly used in gene finding Illustrates how to implement a comparative gene finder, explaining the different steps and various accuracy assessment measures used to debug and benchmark the software A useful text for postgraduate students, this book provides valuable insights and examples for researchers wishing to enter the field quickly. In addition to the specific focus on the algorithmic details surrounding computational gene finding, readers obtain an introduction to the fundamentals of computational biology and biological sequence analysis, as well as an overview of the important mathematical and statistical applications in bioinformatics. Dr. Marina Axelson-Fisk is an Associate Professor at the Department of Mathematical Sciences of Chalmers University of Technology, Gothenburg, Sweden
Member of
Is Subseries of
http://library.link/vocab/creatorName
Axelson-Fisk, Marina
Dewey number
572.860285
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsaut
Zts57CzN4Cs
Language note
English
LC call number
QH324.2-324.25
Literary form
non fiction
Nature of contents
dictionaries
Series statement
Computational Biology,
Series volume
11
http://library.link/vocab/subjectName
  • Bioinformatics
  • Biochemistry
  • Bioinformatics
  • Computational Biology/Bioinformatics
  • Biochemistry, general
Label
Comparative Gene Finding : Models, Algorithms and Implementation, by Marina Axelson-Fisk, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Single Species Gene Finding -- Sequence Alignment -- Comparative Gene Finding -- Gene Structure Submodels -- Parameter Training -- Implementation of a Comparative Gene Finder
Dimensions
unknown
Edition
1st ed. 2010.
Extent
1 online resource (316 p.)
Form of item
online
Isbn
9786612835797
Media category
computer
Media type code
c
Other control number
10.1007/978-1-84996-104-2
Specific material designation
remote
System control number
  • (CKB)2520000000009541
  • (EBL)993239
  • (OCoLC)663093869
  • (SSID)ssj0000414500
  • (PQKBManifestationID)11261860
  • (PQKBTitleCode)TC0000414500
  • (PQKBWorkID)10394463
  • (PQKB)10097927
  • (DE-He213)978-1-84996-104-2
  • (MiAaPQ)EBC993239
  • (EXLCZ)992520000000009541
Label
Comparative Gene Finding : Models, Algorithms and Implementation, by Marina Axelson-Fisk, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Single Species Gene Finding -- Sequence Alignment -- Comparative Gene Finding -- Gene Structure Submodels -- Parameter Training -- Implementation of a Comparative Gene Finder
Dimensions
unknown
Edition
1st ed. 2010.
Extent
1 online resource (316 p.)
Form of item
online
Isbn
9786612835797
Media category
computer
Media type code
c
Other control number
10.1007/978-1-84996-104-2
Specific material designation
remote
System control number
  • (CKB)2520000000009541
  • (EBL)993239
  • (OCoLC)663093869
  • (SSID)ssj0000414500
  • (PQKBManifestationID)11261860
  • (PQKBTitleCode)TC0000414500
  • (PQKBWorkID)10394463
  • (PQKB)10097927
  • (DE-He213)978-1-84996-104-2
  • (MiAaPQ)EBC993239
  • (EXLCZ)992520000000009541

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