The Resource Cerebral Signal Transduction : From First to Fourth Messengers, edited by Maarten E. A. Reith, (electronic resource)

Cerebral Signal Transduction : From First to Fourth Messengers, edited by Maarten E. A. Reith, (electronic resource)

Label
Cerebral Signal Transduction : From First to Fourth Messengers
Title
Cerebral Signal Transduction
Title remainder
From First to Fourth Messengers
Statement of responsibility
edited by Maarten E. A. Reith
Contributor
Editor
Editor
Subject
Language
  • eng
  • eng
Summary
In Cerebral Signal Transduction: From First to Fourth Messengers, Maarten E.A. Reith and a team of leading experts comprehensively review and synthesize the most recent advances in our understanding of the role of cerebral signaling in neuronal and cerebral function. The authors emphasize the functional role of the various signaling pathways in memory, apoptosis and degeneration, depression, and drug dependence in both health and diseases states. The signaling pathways discussed include cAMP/PKA, Ca2+/calmodulin-dependent protein kinase, DAG/PKG, and neurotrophic factor signaling cascades. By taking full advantage of the newfound ability to selectively remove, reduce, or enhance specific components of the signaling pathways, the investigators writing here illuminate the varied signaling cascades, their crosstalk, and the many possibilities for changes in gene expression underlying long-term changes in brain function. Cutting-edge and comprehensive, Cerebral Signal Transduction: From First to Fourth Messengers advances our understanding of the mechanistic underpinnings of complex behavioral processes and clinically relevant brain diseases. A major contribution to the development of the novel pharmacotherapeutics targeting downstream events in the cascade of second, third, and fourth messengers, it will serve experimental and clinical neuroscientists as today's best and most complete guide to neuronal signaling
Member of
Dewey number
612.8
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
Y87jGHnRyqc
Language note
English
LC call number
RC321-580
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Reith, Maarten E. A.
Series statement
Contemporary Neuroscience
http://library.link/vocab/subjectName
  • Neurosciences
  • Neurosciences
Label
Cerebral Signal Transduction : From First to Fourth Messengers, edited by Maarten E. A. Reith, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
I. Introduction -- 1 • From First to Fourth Messengers in the Brain: An Overview -- II. Memory -- 2 • Cellular and Molecular Mechanisms of Learning and Memory -- 3 • Signal Transduction Pathways in Well-Defined Models of Learning and Memory: Drosophila and Honeybee -- 4 • Protein Kinase C Signaling in Learning and Memory -- III. Neurodegeneration and Apoptosis -- 5 • Neurotransmitter Receptor—G-Protein-Mediated Signal Transduction in Alzheimer’s Disease -- 6 • The NO Signaling Pathway in the Brain: Neural Injury, Neurological Disorders, and Aggression -- 7 • Cellular Signaling Pathways in Neuronal Apoptosis: Role in Neurodegeneration and Alzheimer’s Disease -- 8 • The Role of Second Messengers in Neurodegeneration -- IV. Depression -- 9 • Molecular and Cellular Determinants of Stress and Antidepressant Treatment -- 10 • Long-Term Bidirectional Hormonal and Neuroplastic Responses to Stress: Implications for the Treatment of Depression -- 11 • Signal Transduction Abnormalities in Bipolar Affective Disorder -- V. Drug Dependence -- 12 • Messengers in Opioid Dependence: Gene Disruption Studies -- 13 • The 5-HT1B Knockout Mouse: An Animal Model of Vulnerability to Drugs of Abuse -- 14 • Regulation of Dopamine Transporter by Phosphorylation and Impact on Cocaine Action -- 15 • Dopamine Transporter mRNA in Human Brain: Distribution and Regulatory Effects in Autopsy Studies of Cocaine Abusers
Dimensions
unknown
Edition
1st ed. 2000.
Extent
1 online resource (442 p.)
Form of item
online
Isbn
9781592590193
Media category
computer
Media type code
  • c
Other control number
10.1007/978-1-59259-019-3
Specific material designation
remote
System control number
  • (CKB)1000000000476700
  • (EBL)3036706
  • (SSID)ssj0000922980
  • (PQKBManifestationID)11511160
  • (PQKBTitleCode)TC0000922980
  • (PQKBWorkID)10856142
  • (PQKB)10235807
  • (SSID)ssj0000119449
  • (PQKBManifestationID)11992130
  • (PQKBTitleCode)TC0000119449
  • (PQKBWorkID)10058050
  • (PQKB)11188287
  • (DE-He213)978-1-59259-019-3
  • (MiAaPQ)EBC3036706
  • (EXLCZ)991000000000476700
Label
Cerebral Signal Transduction : From First to Fourth Messengers, edited by Maarten E. A. Reith, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Content category
text
Content type code
  • txt
Contents
I. Introduction -- 1 • From First to Fourth Messengers in the Brain: An Overview -- II. Memory -- 2 • Cellular and Molecular Mechanisms of Learning and Memory -- 3 • Signal Transduction Pathways in Well-Defined Models of Learning and Memory: Drosophila and Honeybee -- 4 • Protein Kinase C Signaling in Learning and Memory -- III. Neurodegeneration and Apoptosis -- 5 • Neurotransmitter Receptor—G-Protein-Mediated Signal Transduction in Alzheimer’s Disease -- 6 • The NO Signaling Pathway in the Brain: Neural Injury, Neurological Disorders, and Aggression -- 7 • Cellular Signaling Pathways in Neuronal Apoptosis: Role in Neurodegeneration and Alzheimer’s Disease -- 8 • The Role of Second Messengers in Neurodegeneration -- IV. Depression -- 9 • Molecular and Cellular Determinants of Stress and Antidepressant Treatment -- 10 • Long-Term Bidirectional Hormonal and Neuroplastic Responses to Stress: Implications for the Treatment of Depression -- 11 • Signal Transduction Abnormalities in Bipolar Affective Disorder -- V. Drug Dependence -- 12 • Messengers in Opioid Dependence: Gene Disruption Studies -- 13 • The 5-HT1B Knockout Mouse: An Animal Model of Vulnerability to Drugs of Abuse -- 14 • Regulation of Dopamine Transporter by Phosphorylation and Impact on Cocaine Action -- 15 • Dopamine Transporter mRNA in Human Brain: Distribution and Regulatory Effects in Autopsy Studies of Cocaine Abusers
Dimensions
unknown
Edition
1st ed. 2000.
Extent
1 online resource (442 p.)
Form of item
online
Isbn
9781592590193
Media category
computer
Media type code
  • c
Other control number
10.1007/978-1-59259-019-3
Specific material designation
remote
System control number
  • (CKB)1000000000476700
  • (EBL)3036706
  • (SSID)ssj0000922980
  • (PQKBManifestationID)11511160
  • (PQKBTitleCode)TC0000922980
  • (PQKBWorkID)10856142
  • (PQKB)10235807
  • (SSID)ssj0000119449
  • (PQKBManifestationID)11992130
  • (PQKBTitleCode)TC0000119449
  • (PQKBWorkID)10058050
  • (PQKB)11188287
  • (DE-He213)978-1-59259-019-3
  • (MiAaPQ)EBC3036706
  • (EXLCZ)991000000000476700

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