The Resource Central nervous system diseases : innovative animal models from lab to clinic, edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg, (electronic resource)

Central nervous system diseases : innovative animal models from lab to clinic, edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg, (electronic resource)

Label
Central nervous system diseases : innovative animal models from lab to clinic
Title
Central nervous system diseases
Title remainder
innovative animal models from lab to clinic
Statement of responsibility
edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg
Contributor
Subject
Genre
Language
eng
Summary
In Central Nervous System Diseases: Innovative Animal Models from Lab to Clinic, prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases, as well as their advantages and limitations. Coverage includes novel uses of animal models of Alzheimer's, Parkinson's, and Huntington's diseases, and studies of aging. Techniques that rely heavily on behavioral analyses, as well as models developed from infusions of neurotoxins and from advances in molecular biology are thoroughly explicated, as are models developed for more acute neurological conditions, including traumatic brain injury and stroke. Comprehensive and authoritative, Central Nervous System Diseases: Innovative Animal Models from Lab to Clinic offers neuroscientists, pharmacologists, and interested clinicians a unique survey of the most productive animal models of the leading neurological diseases currently employed to develop today's innovative drug therapies
Member of
Action
digitized
Cataloging source
OCLCE
Dewey number
616.8/0427
Illustrations
illustrations
Index
index present
LC call number
RC361
LC item number
.C44 2000
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2000 D-287
  • WT 155
NLM item number
C397 2000
http://library.link/vocab/relatedWorkOrContributorName
  • Emerich, Dwaine F
  • Dean, Reginald L
  • Sanberg, Paul R
Series statement
Contemporary neuroscience
http://library.link/vocab/subjectName
  • Central nervous system
  • Alzheimer Disease
  • Aging
  • Huntington Disease
  • Models, Biological
  • Parkinson Disease
  • HEALTH & FITNESS
  • MEDICAL
  • Tiermodell
  • Altersphysiologie
  • Alzheimer-Krankheit
  • Huntington-Chorea
  • Parkinson-Krankheit
  • Pathophysiologie
  • Zentralnervensystem
  • Krankheit
Label
Central nervous system diseases : innovative animal models from lab to clinic, edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-691-1
Instantiates
Publication
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1 -- The Cholinergic Hypothesis a Generation Later: Perspectives Gained on the Use and Integration of Animal Models -- 2 -- Patterns of Cognitive Decline in the Aged Rhesus Monkey -- 3 -- Cholinergic Lesions as a Model of Alzheimer's Disease: Effects of Nerve Growth Factor -- 4 -- The Immunolesioned Animal as a Model of Transmitter Dysfunction -- 5 -- An Intracerebral Tumor Necrosis Factor-? Infusion Model for Inflammation in Alzheimer's Disease -- 6 -- The Senescence-Accelerated Mouse as a Possible Animal Model of Senile Dementia -- 7 -- Transgenic Mice Overexpressing Presenilin cDNAs: Phenotype and Utility in the Modeling of Alzheimer's Disease -- 8 -- Intervention Strategies for Degeneration of Dopamine Neurons in Parkinsonism: Optimizing Behavioral Assessment of Outcome -- 9 -- Development of Behavioral Outcome Measures for Preclinical Parkinson's Research -- 10 -- Behavioral Assessment in the Unilateral Dopamine-Depleted Marmoset -- 11 -- Molecules for Neuroprotection and Regeneration in Animal Models of Parkinson's Disease -- 12 -- Antisense Knockdown of Dopamine Receptors -- 13 -- Is Trophic Factor Gene Disruption a 'Knockout' Model for Parkinson's Disease? -- 14 -- Operant Analysis of Striatal Dysfunction -- 15 -- Intrastriatal Injections of Quinolinic Acid as a Model for Developing Neuroprotective Strategies in Huntington's Disease -- 16 -- Systemic Administration of 3-Nitropropionic Acid: A New Model of Huntington's Disease in Rat -- 17 -- Replicating Huntington Disease's Phenotype in Nonhuman Primates -- 18 -- Transgenic Mouse Models of Huntington's Disease -- 19 -- Rigid Indentation Models of Traumatic Brain Injury in the Rat -- 20 -- Rodent Ischemia Models of Embolism and Ligation of the Middle Cerebral Artery: Clinical Relevance to Treatment Strategies of Stroke -- 21 -- A Primate Model of Hypertensive Cerebrovascular Disease -- 22 -- Nictotinic Therapeutics for Tourette Syndrome and Other Neuropsychiatric Disorders: From Laboratory to Clinic -- 23 -- Neural Grafting for Parkinson's and Huntington's Disease -- 24 -- Future Prospects of Gene Therapy for Treating CNS Diseases
Dimensions
unknown
Extent
1 online resource (xv, 512 pages)
File format
one file format
Form of item
online
Isbn
9781617371523
Isbn Type
(print)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-691-1
Other physical details
illustrations.
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
  • (OCoLC)657976372
  • (OCoLC)ocn657976372
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Label
Central nervous system diseases : innovative animal models from lab to clinic, edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-691-1
Publication
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1 -- The Cholinergic Hypothesis a Generation Later: Perspectives Gained on the Use and Integration of Animal Models -- 2 -- Patterns of Cognitive Decline in the Aged Rhesus Monkey -- 3 -- Cholinergic Lesions as a Model of Alzheimer's Disease: Effects of Nerve Growth Factor -- 4 -- The Immunolesioned Animal as a Model of Transmitter Dysfunction -- 5 -- An Intracerebral Tumor Necrosis Factor-? Infusion Model for Inflammation in Alzheimer's Disease -- 6 -- The Senescence-Accelerated Mouse as a Possible Animal Model of Senile Dementia -- 7 -- Transgenic Mice Overexpressing Presenilin cDNAs: Phenotype and Utility in the Modeling of Alzheimer's Disease -- 8 -- Intervention Strategies for Degeneration of Dopamine Neurons in Parkinsonism: Optimizing Behavioral Assessment of Outcome -- 9 -- Development of Behavioral Outcome Measures for Preclinical Parkinson's Research -- 10 -- Behavioral Assessment in the Unilateral Dopamine-Depleted Marmoset -- 11 -- Molecules for Neuroprotection and Regeneration in Animal Models of Parkinson's Disease -- 12 -- Antisense Knockdown of Dopamine Receptors -- 13 -- Is Trophic Factor Gene Disruption a 'Knockout' Model for Parkinson's Disease? -- 14 -- Operant Analysis of Striatal Dysfunction -- 15 -- Intrastriatal Injections of Quinolinic Acid as a Model for Developing Neuroprotective Strategies in Huntington's Disease -- 16 -- Systemic Administration of 3-Nitropropionic Acid: A New Model of Huntington's Disease in Rat -- 17 -- Replicating Huntington Disease's Phenotype in Nonhuman Primates -- 18 -- Transgenic Mouse Models of Huntington's Disease -- 19 -- Rigid Indentation Models of Traumatic Brain Injury in the Rat -- 20 -- Rodent Ischemia Models of Embolism and Ligation of the Middle Cerebral Artery: Clinical Relevance to Treatment Strategies of Stroke -- 21 -- A Primate Model of Hypertensive Cerebrovascular Disease -- 22 -- Nictotinic Therapeutics for Tourette Syndrome and Other Neuropsychiatric Disorders: From Laboratory to Clinic -- 23 -- Neural Grafting for Parkinson's and Huntington's Disease -- 24 -- Future Prospects of Gene Therapy for Treating CNS Diseases
Dimensions
unknown
Extent
1 online resource (xv, 512 pages)
File format
one file format
Form of item
online
Isbn
9781617371523
Isbn Type
(print)
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-59259-691-1
Other physical details
illustrations.
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
  • (OCoLC)657976372
  • (OCoLC)ocn657976372
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

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