Coverart for item
The Resource Blood-Brain Barrier Permeability Changes after Subarachnoid Haemorrhage: An Update : Clinical Implications, Experimental Findings, Challenges and Future Directions, by Antonino F. Germanò, Francesco Tomasello, (electronic resource)

Blood-Brain Barrier Permeability Changes after Subarachnoid Haemorrhage: An Update : Clinical Implications, Experimental Findings, Challenges and Future Directions, by Antonino F. Germanò, Francesco Tomasello, (electronic resource)

Label
Blood-Brain Barrier Permeability Changes after Subarachnoid Haemorrhage: An Update : Clinical Implications, Experimental Findings, Challenges and Future Directions
Title
Blood-Brain Barrier Permeability Changes after Subarachnoid Haemorrhage: An Update
Title remainder
Clinical Implications, Experimental Findings, Challenges and Future Directions
Statement of responsibility
by Antonino F. Germanò, Francesco Tomasello
Creator
Contributor
Subject
Genre
Language
eng
Summary
This monograph constitutes a comprehensive overview of BBB permeability changes and related damaging sequelae associated with subarachnoid haemorrhage. Despite improvements in the surgical and clinical management patients still experience an unacceptably high morbidity and mortality linked to the presence of subarachnoid blood. In this monograph, the authors have reviewed the historical basis of this problem, the anatomical substrates of the BBB, the occurrence and adverse consequences of barrier disruption following SAH, the related sequelae of oedema formation, ICP alteration and vasospasm discussed from both the basic science and clinical perspective, with the consideration of multiple clinical and laboratory investigative tools, including all aspects of modern imaging. The text is supplemented by presenting key research publications in the field, focusing on the damaging consequences of subarachnoid blood, while attempting to explain the hierarchy of events in those progressive changes associated with blood-brain barrier perturbation, including vasospasm, ischaemia and elevated intracranial pressure
Cataloging source
AU@
http://library.link/vocab/creatorName
Germanò, Antonino F
Dewey number
617.48
Illustrations
illustrations
Index
no index present
LC call number
RD592.5-596
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Tomasello, Francesco
http://library.link/vocab/subjectName
  • Medicine
  • Neurosciences
  • Toxicology
  • Pharmacy
  • Neurology
  • Nervous system
  • Pathology
  • Medicine
  • Nervous system
  • Neurology
  • Neurosciences
  • Pathology
  • Pharmacy
  • Toxicology
Label
Blood-Brain Barrier Permeability Changes after Subarachnoid Haemorrhage: An Update : Clinical Implications, Experimental Findings, Challenges and Future Directions, by Antonino F. Germanò, Francesco Tomasello, (electronic resource)
Link
http://dx.doi.org/10.1007/978-3-7091-6194-4
Instantiates
Publication
Antecedent source
file reproduced from original
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
The Concept of the BBB: A Historical Perspective -- Anatomy of the BBB -- Pathophysiology of BBB: Brain Oedema; Breakdown of the BBB -- BBB Dysfunction after SAH: Clinical Monitoring -- Neuroradiological Findings of BBB Dysfunction after SAH: Computerised Tomography and Magnetic Resonance SPECT and PET -- Experimental Data: Literature Review of BBB Dysfunction after Experimental SAH; Qualitative Assessments of BBB Dysfunction after SAH; Quantitative Assessments of BBB Dysfunction; Time Course of BBB Dysfunction after SAH; Additional Pathophysiological Changes after SAH -- Strategies for Pharmacological Intervention: Hydroxyl Radical Scavenger AVS; Glutamate Antagonist Felbamate; Calpain Inhibitor II -- Challenges and Future Direction: Advances in Cerebrovascular Pathophysiology; Gene Therapy
Dimensions
unknown
Extent
1 online resource (x, 130 pages 41 illustrations)
File format
unknown
Form of item
online
Isbn
9783709161944
Isbn Type
(electronic bk.)
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-7091-6194-4
Quality assurance targets
unknown
Reformatting quality
access
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)851389330
  • (OCoLC)ocn851389330
Label
Blood-Brain Barrier Permeability Changes after Subarachnoid Haemorrhage: An Update : Clinical Implications, Experimental Findings, Challenges and Future Directions, by Antonino F. Germanò, Francesco Tomasello, (electronic resource)
Link
http://dx.doi.org/10.1007/978-3-7091-6194-4
Publication
Antecedent source
file reproduced from original
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
The Concept of the BBB: A Historical Perspective -- Anatomy of the BBB -- Pathophysiology of BBB: Brain Oedema; Breakdown of the BBB -- BBB Dysfunction after SAH: Clinical Monitoring -- Neuroradiological Findings of BBB Dysfunction after SAH: Computerised Tomography and Magnetic Resonance SPECT and PET -- Experimental Data: Literature Review of BBB Dysfunction after Experimental SAH; Qualitative Assessments of BBB Dysfunction after SAH; Quantitative Assessments of BBB Dysfunction; Time Course of BBB Dysfunction after SAH; Additional Pathophysiological Changes after SAH -- Strategies for Pharmacological Intervention: Hydroxyl Radical Scavenger AVS; Glutamate Antagonist Felbamate; Calpain Inhibitor II -- Challenges and Future Direction: Advances in Cerebrovascular Pathophysiology; Gene Therapy
Dimensions
unknown
Extent
1 online resource (x, 130 pages 41 illustrations)
File format
unknown
Form of item
online
Isbn
9783709161944
Isbn Type
(electronic bk.)
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-7091-6194-4
Quality assurance targets
unknown
Reformatting quality
access
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)851389330
  • (OCoLC)ocn851389330

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