The Resource Biophysics of DNA-Protein Interactions : From Single Molecules to Biological Systems, edited by Mark C. Williams, L. James Maher, III, (electronic resource)

Biophysics of DNA-Protein Interactions : From Single Molecules to Biological Systems, edited by Mark C. Williams, L. James Maher, III, (electronic resource)

Label
Biophysics of DNA-Protein Interactions : From Single Molecules to Biological Systems
Title
Biophysics of DNA-Protein Interactions
Title remainder
From Single Molecules to Biological Systems
Statement of responsibility
edited by Mark C. Williams, L. James Maher, III
Contributor
Editor
Editor
Subject
Language
  • eng
  • eng
Summary
This book presents a concise overview of current research on the biophysics of DNA-protein interactions. A wide range of new and classical methods are presented by authors investigating physical mechanisms by which proteins interact with DNA. For example, several chapters address the mechanisms by which proteins search for and recognize specific binding sites on DNA, a process critical for cellular function. Single molecule methods such as force spectroscopy as well as fluorescence imaging and tracking are described in these chapters as well as other parts of the book that address the dynamics of protein-DNA interactions. Other important topics include the mechanisms by which proteins engage DNA sequences and/or alter DNA structure. These simple but important model interactions are then placed in the broader biological context with discussion of larger protein-DNA complexes . Topics include replication forks, recombination complexes, DNA repair interactions, and ultimately, methods to understand the chromatin context of the cell nucleus. This book will be of interest to readers who wish to explore current biophysical approaches to DNA-protein interactions across multiple levels of biological complexity
Member of
Is Subseries of
Dewey number
572.864
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
  • vq8cBYvkl-U
  • -mLZa3KNiBI
Language note
English
LC call number
QH505
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Williams, Mark C.
  • Maher, III, L. James.
Series statement
Biological and Medical Physics, Biomedical Engineering,
http://library.link/vocab/subjectName
  • Medicine
  • Cytology
  • Biomedical engineering
  • Biochemistry
  • Biological and Medical Physics, Biophysics
  • Molecular Medicine
  • Cell Biology
  • Biomedical Engineering and Bioengineering
  • Biochemistry, general
  • Protein Structure
Label
Biophysics of DNA-Protein Interactions : From Single Molecules to Biological Systems, edited by Mark C. Williams, L. James Maher, III, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Introduction -- Nonspecific DNA Binding: Searching DNA and Altering DNA Properties -- DNA Search Theory -- DNA Search, Hopping vs. Sliding -- SSB DNA Search -- HN-S Proteins or DNA Sliding Search -- Processivity Clamp -- DNA Bending Proteins -- Kinetics of DNA Binding and Bending by Proteins -- Modes of DNA Interaction by Architectural Proteins -- Complex Protein-DNA Interactions -- DNA Looping by Repressor Proteins -- NF-kappaB Transcription Factor Crystallography -- Replication Complex -- DNA Recombination Complexes -- DNA Binding by Alkyltransferase Repair Proteins -- DNA Polymerase Crystallography -- Polymerase Switching in Response to DNA Damage -- Single Molecule Studies on Chromatin -- Regulation of Chromosome Conformation in Cells -- Nucleosome Positioning Across Genomes
Dimensions
unknown
Edition
1st ed. 2011.
Extent
1 online resource (353 p.)
Form of item
online
Isbn
9781282973848
Media category
computer
Media type code
c
Other control number
10.1007/978-0-387-92808-1
Specific material designation
remote
System control number
  • (CKB)2550000000020045
  • (EBL)645829
  • (OCoLC)682907402
  • (SSID)ssj0000449106
  • (PQKBManifestationID)11280719
  • (PQKBTitleCode)TC0000449106
  • (PQKBWorkID)10428763
  • (PQKB)11729966
  • (DE-He213)978-0-387-92808-1
  • (MiAaPQ)EBC645829
  • (EXLCZ)992550000000020045
Label
Biophysics of DNA-Protein Interactions : From Single Molecules to Biological Systems, edited by Mark C. Williams, L. James Maher, III, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Introduction -- Nonspecific DNA Binding: Searching DNA and Altering DNA Properties -- DNA Search Theory -- DNA Search, Hopping vs. Sliding -- SSB DNA Search -- HN-S Proteins or DNA Sliding Search -- Processivity Clamp -- DNA Bending Proteins -- Kinetics of DNA Binding and Bending by Proteins -- Modes of DNA Interaction by Architectural Proteins -- Complex Protein-DNA Interactions -- DNA Looping by Repressor Proteins -- NF-kappaB Transcription Factor Crystallography -- Replication Complex -- DNA Recombination Complexes -- DNA Binding by Alkyltransferase Repair Proteins -- DNA Polymerase Crystallography -- Polymerase Switching in Response to DNA Damage -- Single Molecule Studies on Chromatin -- Regulation of Chromosome Conformation in Cells -- Nucleosome Positioning Across Genomes
Dimensions
unknown
Edition
1st ed. 2011.
Extent
1 online resource (353 p.)
Form of item
online
Isbn
9781282973848
Media category
computer
Media type code
c
Other control number
10.1007/978-0-387-92808-1
Specific material designation
remote
System control number
  • (CKB)2550000000020045
  • (EBL)645829
  • (OCoLC)682907402
  • (SSID)ssj0000449106
  • (PQKBManifestationID)11280719
  • (PQKBTitleCode)TC0000449106
  • (PQKBWorkID)10428763
  • (PQKB)11729966
  • (DE-He213)978-0-387-92808-1
  • (MiAaPQ)EBC645829
  • (EXLCZ)992550000000020045

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