The Resource Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene, by Amita Kashyap, D. Bujamma, Naresh Babu M, (electronic resource)

Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene, by Amita Kashyap, D. Bujamma, Naresh Babu M, (electronic resource)

Label
Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene
Title
Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene
Statement of responsibility
by Amita Kashyap, D. Bujamma, Naresh Babu M
Creator
Contributor
Author
Author
Subject
Language
  • eng
  • eng
Summary
Cancer is initiated by activation of oncogenes or inactivation of tumor suppressor genes. Mutations in the K-ras proto-oncogene are responsible for 10–30% of adenocarcinomas. Clinical Findings point to a wide variety of other cancers contributing to lung cancer incidence. Such a scenario makes identification of lung cancer difficult and thus identifying its mechanisms can contribute to the society. Identifying unique conserved patterns common to contributing proto-oncogenes may further be a boon to Pharmacogenomics and pharmacoinformatics. This calls for ab initio/de novo drug discovery that in turn will require a comprehensive in silico approach of Sequence, Domain, Phylogenetic and Structural analysis of the receptors, ligand screening and optimization and detailed Docking studies. This brief involves extensive role of the RAS subfamily that includes a set of proteins, which cause an over expression of cancer-causing genes like M-ras and initiate tumour formation in lungs. SNP Studies and Structure based drug discovery will also be undertaken
Member of
http://library.link/vocab/creatorName
Kashyap, Amita
Dewey number
  • 006.3
  • 502.85
  • 519
  • 570285
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsaut
  • PrJavZgzcMk
  • tNo0gZvPShE
  • pK0mXrsnCFA
Language note
English
LC call number
Q342
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Bujamma, D.
  • Babu M, Naresh.
Series statement
SpringerBriefs in Forensic and Medical Bioinformatics,
http://library.link/vocab/subjectName
  • Engineering
  • Bioinformatics
  • Oncology
  • Biomedical engineering
  • Medical records
  • Engineering mathematics
  • Computational Intelligence
  • Computational Biology/Bioinformatics
  • Cancer Research
  • Biomedical Engineering and Bioengineering
  • Health Informatics
  • Mathematical and Computational Engineering
Label
Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene, by Amita Kashyap, D. Bujamma, Naresh Babu M, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Introduction -- Review of Literature -- Materials and Methods (Tools and Databases) -- Flowchart -- Conclusion.-References
Dimensions
unknown
Edition
1st ed. 2015.
Extent
1 online resource (79 p.)
Form of item
online
Isbn
9789814585088
Media category
computer
Media type code
c
Other control number
10.1007/978-981-4585-08-8
Specific material designation
remote
System control number
  • (CKB)3710000000230899
  • (EBL)1968522
  • (OCoLC)907300525
  • (SSID)ssj0001353941
  • (PQKBManifestationID)11779897
  • (PQKBTitleCode)TC0001353941
  • (PQKBWorkID)11323375
  • (PQKB)10341561
  • (DE-He213)978-981-4585-08-8
  • (MiAaPQ)EBC1968522
  • (EXLCZ)993710000000230899
Label
Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene, by Amita Kashyap, D. Bujamma, Naresh Babu M, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Introduction -- Review of Literature -- Materials and Methods (Tools and Databases) -- Flowchart -- Conclusion.-References
Dimensions
unknown
Edition
1st ed. 2015.
Extent
1 online resource (79 p.)
Form of item
online
Isbn
9789814585088
Media category
computer
Media type code
c
Other control number
10.1007/978-981-4585-08-8
Specific material designation
remote
System control number
  • (CKB)3710000000230899
  • (EBL)1968522
  • (OCoLC)907300525
  • (SSID)ssj0001353941
  • (PQKBManifestationID)11779897
  • (PQKBTitleCode)TC0001353941
  • (PQKBWorkID)11323375
  • (PQKB)10341561
  • (DE-He213)978-981-4585-08-8
  • (MiAaPQ)EBC1968522
  • (EXLCZ)993710000000230899

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