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The Resource Bacteriophage applications : historical perspective and future potential, Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev

Bacteriophage applications : historical perspective and future potential, Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev

Author
Contributor
Summary
This book explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field. The small size and enormous diversity of bacteriophages make them ideal candidates for numerous applications across many industries. Since the discovery of phages and the advent of phage display systems, considerable attention has been focused on the development of novel therapeutic and industrial applications. Recent studies combine the genomic flexibility of phages with phage display systems in order to generate modified phages for targeted delivery
Language
eng
Work
Publication
Extent
1 online resource (vii, 82 pages).
Contents
  • 1 Overview of Bacteriophage Lifecycles and Applications; 1 Introduction; 2 Phage Infection and Life-Cycle; 2.1 Lytic Phage; 2.2 Temperate Phage; 3 Phage Infection Stages; 3.1 Phage Entry; 3.2 DNA Replication; 3.3 Phage Assembly; 3.3.1 Tailed (dsDNA) Phages; 3.3.2 ssDNA Phages; 3.3.3 ssRNA Phages; 4 Hurdles for Phage-Based Therapeutics; References; 2 Phage for Biocontrol; Abstract; 1 Introduction; 2 The Importance of Using Recombinant Phage; 3 Recombinant Phage for the Treatment of Bacterial Infections; 3.1 Escherichia coli (E. coli); 3.2 Staphylococcus aureus (S. aureus)
  • 3.3 Chlamydia trachomatis3.4 Pseudomonas aeruginosa (PA); 3.5 Helicobacter pylori (H. pylori); 4 Phage as Drug Delivery Vehicles for the Treatment of Bacterial Infections; 5 Summary; References; 3 Phage Device Coatings; Abstract; 1 Introduction; 2 Biofilms on Medical Devices; 2.1 Contributors to Biofilm Resistance; 3 Alternative Medical Coating Devices; 4 Bacteriophage as Bioactive Coatings; 5 Conclusions; References; 4 Bacteriophages Functionalized for Gene Delivery and the Targeting of Gene Networks; Abstract; 1 Introduction to Phage Mediated Delivery of Genetic Material
  • 2 Bacteriophages as Gene Delivery Vehicles3 Phages as Cytotoxic Agents in Eukaryotes; 4 Phages for Delivery to the Central Nervous System; 5 Conclusions; References; 5 Phage Probiotics; Abstract; 1 Introduction: The Gut Microbiota and Probiotics; 2 Roles of the Gut Microbiota and Probiotics; 2.1 Protection Against Pathogens; 2.2 Metabolism; 2.3 Immunomodulation; 2.4 Tissue Development and Maintenance; 3 Bacteriophages in the Gut; 3.1 Phage Population Dynamics; 3.2 Protection Against Pathogens and Immunomodulation; 4 Applications of Phage; 4.1 Lytic Phage Therapy; 4.2 Phage Biotechnology
  • 5 ConclusionsReferences; 6 Phage for Biodetection; Abstract; 1 Introduction to Phage-Based Biodetection; 2 Plaque Assays; 2.1 Phage Display for the Improvement of Plaque Assays; 3 Bacteriophage Indicator Organisms (Reporter Phage); 3.1 Fluorescence-Based Assays; 4 Immobilized Phage Particles as Probes for Bacterial Detection; 5 Conclusions; References; 7 Phage-Mediated Immunomodulation; 1 Introduction; 2 Immune Responses to Phage; 2.1 Anti-phage Innate Responses; 2.2 Humoral Immune Reposes to Phage (Anti-phage Antibodies)
  • 2.3 Anti-phage Cellular Immunity and the Implications of the Impact of Phage on the Adaptive Responses (T and B Cells)3 Bacteriophage-Based Immune-Pharmaco-Therapies; 3.1 Phage Immunogenicity and Cancer Therapy; 3.1.1 Phage in Tumor Targeting; 3.1.2 Anti-tumor Phage Therapies; 3.2 Bacteriophage Immunotherapy Autoimmune Disorders; 3.3 Bacteriophage Immunotherapy for Drug Addiction; 3.4 Phages and Oxidative Stress; 4 Conclusions; References
Isbn
9783319457918
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-319-45791-8
Instance
Label
Bacteriophage applications : historical perspective and future potential
Title
Bacteriophage applications
Title remainder
historical perspective and future potential
Statement of responsibility
Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev
Contributor
Author
Subject
Genre
Language
eng
Summary
This book explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field. The small size and enormous diversity of bacteriophages make them ideal candidates for numerous applications across many industries. Since the discovery of phages and the advent of phage display systems, considerable attention has been focused on the development of novel therapeutic and industrial applications. Recent studies combine the genomic flexibility of phages with phage display systems in order to generate modified phages for targeted delivery
Member of
Cataloging source
GW5XE
Dewey number
579.2/6
Illustrations
illustrations
Index
no index present
LC call number
QR342
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Nicastro, Jessica
  • Wong, Shirley
  • Khazaei, Zahra
  • Lam, Peggy
  • Blay, Jonathan
  • Slavcev, Roderick A.
Series statement
SpringerBriefs in biochemistry and molecular biology,
http://library.link/vocab/subjectName
  • Bacteriophages
  • SCIENCE
  • SCIENCE
  • Bacteriophages
  • Biochemistry
  • Medical genetics
  • Biochemical engineering
Label
Bacteriophage applications : historical perspective and future potential, Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-319-45791-8
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • 1 Overview of Bacteriophage Lifecycles and Applications; 1 Introduction; 2 Phage Infection and Life-Cycle; 2.1 Lytic Phage; 2.2 Temperate Phage; 3 Phage Infection Stages; 3.1 Phage Entry; 3.2 DNA Replication; 3.3 Phage Assembly; 3.3.1 Tailed (dsDNA) Phages; 3.3.2 ssDNA Phages; 3.3.3 ssRNA Phages; 4 Hurdles for Phage-Based Therapeutics; References; 2 Phage for Biocontrol; Abstract; 1 Introduction; 2 The Importance of Using Recombinant Phage; 3 Recombinant Phage for the Treatment of Bacterial Infections; 3.1 Escherichia coli (E. coli); 3.2 Staphylococcus aureus (S. aureus)
  • 3.3 Chlamydia trachomatis3.4 Pseudomonas aeruginosa (PA); 3.5 Helicobacter pylori (H. pylori); 4 Phage as Drug Delivery Vehicles for the Treatment of Bacterial Infections; 5 Summary; References; 3 Phage Device Coatings; Abstract; 1 Introduction; 2 Biofilms on Medical Devices; 2.1 Contributors to Biofilm Resistance; 3 Alternative Medical Coating Devices; 4 Bacteriophage as Bioactive Coatings; 5 Conclusions; References; 4 Bacteriophages Functionalized for Gene Delivery and the Targeting of Gene Networks; Abstract; 1 Introduction to Phage Mediated Delivery of Genetic Material
  • 2 Bacteriophages as Gene Delivery Vehicles3 Phages as Cytotoxic Agents in Eukaryotes; 4 Phages for Delivery to the Central Nervous System; 5 Conclusions; References; 5 Phage Probiotics; Abstract; 1 Introduction: The Gut Microbiota and Probiotics; 2 Roles of the Gut Microbiota and Probiotics; 2.1 Protection Against Pathogens; 2.2 Metabolism; 2.3 Immunomodulation; 2.4 Tissue Development and Maintenance; 3 Bacteriophages in the Gut; 3.1 Phage Population Dynamics; 3.2 Protection Against Pathogens and Immunomodulation; 4 Applications of Phage; 4.1 Lytic Phage Therapy; 4.2 Phage Biotechnology
  • 5 ConclusionsReferences; 6 Phage for Biodetection; Abstract; 1 Introduction to Phage-Based Biodetection; 2 Plaque Assays; 2.1 Phage Display for the Improvement of Plaque Assays; 3 Bacteriophage Indicator Organisms (Reporter Phage); 3.1 Fluorescence-Based Assays; 4 Immobilized Phage Particles as Probes for Bacterial Detection; 5 Conclusions; References; 7 Phage-Mediated Immunomodulation; 1 Introduction; 2 Immune Responses to Phage; 2.1 Anti-phage Innate Responses; 2.2 Humoral Immune Reposes to Phage (Anti-phage Antibodies)
  • 2.3 Anti-phage Cellular Immunity and the Implications of the Impact of Phage on the Adaptive Responses (T and B Cells)3 Bacteriophage-Based Immune-Pharmaco-Therapies; 3.1 Phage Immunogenicity and Cancer Therapy; 3.1.1 Phage in Tumor Targeting; 3.1.2 Anti-tumor Phage Therapies; 3.2 Bacteriophage Immunotherapy Autoimmune Disorders; 3.3 Bacteriophage Immunotherapy for Drug Addiction; 3.4 Phages and Oxidative Stress; 4 Conclusions; References
Dimensions
unknown
Extent
1 online resource (vii, 82 pages).
File format
unknown
Form of item
online
Isbn
9783319457918
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-3-319-45791-8
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)960701407
  • (OCoLC)ocn960701407
Label
Bacteriophage applications : historical perspective and future potential, Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-3-319-45791-8
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • 1 Overview of Bacteriophage Lifecycles and Applications; 1 Introduction; 2 Phage Infection and Life-Cycle; 2.1 Lytic Phage; 2.2 Temperate Phage; 3 Phage Infection Stages; 3.1 Phage Entry; 3.2 DNA Replication; 3.3 Phage Assembly; 3.3.1 Tailed (dsDNA) Phages; 3.3.2 ssDNA Phages; 3.3.3 ssRNA Phages; 4 Hurdles for Phage-Based Therapeutics; References; 2 Phage for Biocontrol; Abstract; 1 Introduction; 2 The Importance of Using Recombinant Phage; 3 Recombinant Phage for the Treatment of Bacterial Infections; 3.1 Escherichia coli (E. coli); 3.2 Staphylococcus aureus (S. aureus)
  • 3.3 Chlamydia trachomatis3.4 Pseudomonas aeruginosa (PA); 3.5 Helicobacter pylori (H. pylori); 4 Phage as Drug Delivery Vehicles for the Treatment of Bacterial Infections; 5 Summary; References; 3 Phage Device Coatings; Abstract; 1 Introduction; 2 Biofilms on Medical Devices; 2.1 Contributors to Biofilm Resistance; 3 Alternative Medical Coating Devices; 4 Bacteriophage as Bioactive Coatings; 5 Conclusions; References; 4 Bacteriophages Functionalized for Gene Delivery and the Targeting of Gene Networks; Abstract; 1 Introduction to Phage Mediated Delivery of Genetic Material
  • 2 Bacteriophages as Gene Delivery Vehicles3 Phages as Cytotoxic Agents in Eukaryotes; 4 Phages for Delivery to the Central Nervous System; 5 Conclusions; References; 5 Phage Probiotics; Abstract; 1 Introduction: The Gut Microbiota and Probiotics; 2 Roles of the Gut Microbiota and Probiotics; 2.1 Protection Against Pathogens; 2.2 Metabolism; 2.3 Immunomodulation; 2.4 Tissue Development and Maintenance; 3 Bacteriophages in the Gut; 3.1 Phage Population Dynamics; 3.2 Protection Against Pathogens and Immunomodulation; 4 Applications of Phage; 4.1 Lytic Phage Therapy; 4.2 Phage Biotechnology
  • 5 ConclusionsReferences; 6 Phage for Biodetection; Abstract; 1 Introduction to Phage-Based Biodetection; 2 Plaque Assays; 2.1 Phage Display for the Improvement of Plaque Assays; 3 Bacteriophage Indicator Organisms (Reporter Phage); 3.1 Fluorescence-Based Assays; 4 Immobilized Phage Particles as Probes for Bacterial Detection; 5 Conclusions; References; 7 Phage-Mediated Immunomodulation; 1 Introduction; 2 Immune Responses to Phage; 2.1 Anti-phage Innate Responses; 2.2 Humoral Immune Reposes to Phage (Anti-phage Antibodies)
  • 2.3 Anti-phage Cellular Immunity and the Implications of the Impact of Phage on the Adaptive Responses (T and B Cells)3 Bacteriophage-Based Immune-Pharmaco-Therapies; 3.1 Phage Immunogenicity and Cancer Therapy; 3.1.1 Phage in Tumor Targeting; 3.1.2 Anti-tumor Phage Therapies; 3.2 Bacteriophage Immunotherapy Autoimmune Disorders; 3.3 Bacteriophage Immunotherapy for Drug Addiction; 3.4 Phages and Oxidative Stress; 4 Conclusions; References
Dimensions
unknown
Extent
1 online resource (vii, 82 pages).
File format
unknown
Form of item
online
Isbn
9783319457918
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-3-319-45791-8
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)960701407
  • (OCoLC)ocn960701407

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