The Resource Apoptosis, Senescence, and Cancer, edited by David A. Gewirtz, Shawn E. Holt, Steven Grant, (electronic resource)

Apoptosis, Senescence, and Cancer, edited by David A. Gewirtz, Shawn E. Holt, Steven Grant, (electronic resource)

Label
Apoptosis, Senescence, and Cancer
Title
Apoptosis, Senescence, and Cancer
Statement of responsibility
edited by David A. Gewirtz, Shawn E. Holt, Steven Grant
Contributor
Editor
Editor
Subject
Language
  • eng
  • eng
Summary
Apoptosis, Senescence and Cancer provides insight into established practices and research into apoptosis and senescence by thoroughly examining novel and emerging techniques and research in the fields of cell death pathways, senescence growth arrest, drugs and resistance, DNA damage response, and other topics which still hold mysteries for researchers. The volume is divided into six easy to follow sections. The first is Apoptosis and Alternative Modes of Cell Death, followed by chapters on Telomeres and Telomerase, Senescence, Genomic Instability and Tumorigenesis. The third part covers DNA Damage Response, Signaling Pathways and Tumorigenesis, while the fourth delves into Resistance and Sensitization. The book concludes with Established Cancer Therapies and a section which looks toward the future with Recent and Developing Cancer Therapies. In total, this volume provides basic scientists and clinicians with a deeper and more complete understanding of the cellular responses of malignancies which may determine the effectiveness of treatment, both in the initial stages of the disease as well as in disease recurrence
Member of
Is Subseries of
Dewey number
  • 616.99/4061
  • 616.99407
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
  • ftQ0s9qm0ps
  • j6qPw1GLXek
  • Swgz7a5QMQc
Language note
English
LC call number
RM845-862.5
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Gewirtz, David A.
  • Holt, Shawn E.
  • Grant, Steven.
Series statement
Cancer Drug Discovery and Development,
http://library.link/vocab/subjectName
  • Radiotherapy
  • Oncology
  • Oncology
  • Nuclear medicine
  • Toxicology
  • Radiotherapy
  • Cancer Research
  • Oncology
  • Nuclear Medicine
  • Pharmacology/Toxicology
Label
Apoptosis, Senescence, and Cancer, edited by David A. Gewirtz, Shawn E. Holt, Steven Grant, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Apoptosis and Alternative Modes of Cell Death -- The Intrinsic Pathway of Apoptosis -- The Extrinsic Pathway of Apoptosis -- Evaluating the Importance of Apoptosis and Other Determinants of Cell Death and Survival -- Mitotic Catastrophe -- Autophagy and Autophagic Cell Death -- Regulation and Function of Detachment-Induced Cell Death (Anoikis) in Cancer Progression and Metastasis -- Telomeres and Telomerase, Senescence, Genomic Instability, and Tumorigenesis -- Structure and Function of the Telomere -- Overview of Senescence -- Contributions of Telomerase to Tumorigenesis -- The Role of Telomeres in Genomic Instability -- DNA Damage Response, Signaling Pathways, and Tumorigenesis -- Overview of the DNA Damage Checkpoint -- Interactions Between Myc- and Cyclin-Dependent Kinase Inhibitors in Cancer -- Interplay Between ?H2AX and 53BP1 Pathways in DNA Double-Strand Break Repair Response -- DNA-Dependent Protein Kinase in Repair, Apoptosis, Telomere Maintenance, and Chemotherapy -- Resistance and Sensitization -- Resistance/Signaling Pathways -- Ceramide and Multidrug Resistance -- Chemo- and Radiosensitization Through Inhibition of PI3K/Akt Signaling -- The Advancement of Epidermal Growth Factor Receptor Inhibitors in Cancer Therapy -- Established Cancer Therapies -- Antimetabolites -- Topoisomerase I Poisons and Apoptotic Topoisomerase I-DNA Complexes -- Perturbations of Cellular Functions by Topoisomerase II Inhibitors -- The Significance of Poly-Targeting in Apoptosis Induction by Alkylating Agents and Platinum Drugs -- Contributions of Apoptosis and Senescence to Cytotoxicity Produced by Microtubule-Stabilizing Agents -- Tyrosine Kinase Inhibitors -- Recent and Developing Cancer Therapies -- Monoclonal Antibodies in Lymphomas -- Role of Apoptosis in Anti-Angiogenic Cancer Therapies -- Photodynamic Therapy-Induced Apoptosis -- Modulation of TRAIL Signaling for Cancer Therapy
Dimensions
unknown
Edition
2nd ed.
Extent
1 online resource (613 p.)
Form of item
online
Isbn
9781281116895
Media category
computer
Media type code
c
Other control number
10.1007/978-1-59745-221-2
Specific material designation
remote
System control number
  • (CKB)1000000000405446
  • (EBL)371394
  • (OCoLC)808729138
  • (SSID)ssj0000768081
  • (PQKBManifestationID)12387795
  • (PQKBTitleCode)TC0000768081
  • (PQKBWorkID)10742467
  • (PQKB)10691301
  • (SSID)ssj0000104510
  • (PQKBManifestationID)11140829
  • (PQKBTitleCode)TC0000104510
  • (PQKBWorkID)10079345
  • (PQKB)11751942
  • (DE-He213)978-1-59745-221-2
  • (MiAaPQ)EBC371394
  • (EXLCZ)991000000000405446
Label
Apoptosis, Senescence, and Cancer, edited by David A. Gewirtz, Shawn E. Holt, Steven Grant, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Apoptosis and Alternative Modes of Cell Death -- The Intrinsic Pathway of Apoptosis -- The Extrinsic Pathway of Apoptosis -- Evaluating the Importance of Apoptosis and Other Determinants of Cell Death and Survival -- Mitotic Catastrophe -- Autophagy and Autophagic Cell Death -- Regulation and Function of Detachment-Induced Cell Death (Anoikis) in Cancer Progression and Metastasis -- Telomeres and Telomerase, Senescence, Genomic Instability, and Tumorigenesis -- Structure and Function of the Telomere -- Overview of Senescence -- Contributions of Telomerase to Tumorigenesis -- The Role of Telomeres in Genomic Instability -- DNA Damage Response, Signaling Pathways, and Tumorigenesis -- Overview of the DNA Damage Checkpoint -- Interactions Between Myc- and Cyclin-Dependent Kinase Inhibitors in Cancer -- Interplay Between ?H2AX and 53BP1 Pathways in DNA Double-Strand Break Repair Response -- DNA-Dependent Protein Kinase in Repair, Apoptosis, Telomere Maintenance, and Chemotherapy -- Resistance and Sensitization -- Resistance/Signaling Pathways -- Ceramide and Multidrug Resistance -- Chemo- and Radiosensitization Through Inhibition of PI3K/Akt Signaling -- The Advancement of Epidermal Growth Factor Receptor Inhibitors in Cancer Therapy -- Established Cancer Therapies -- Antimetabolites -- Topoisomerase I Poisons and Apoptotic Topoisomerase I-DNA Complexes -- Perturbations of Cellular Functions by Topoisomerase II Inhibitors -- The Significance of Poly-Targeting in Apoptosis Induction by Alkylating Agents and Platinum Drugs -- Contributions of Apoptosis and Senescence to Cytotoxicity Produced by Microtubule-Stabilizing Agents -- Tyrosine Kinase Inhibitors -- Recent and Developing Cancer Therapies -- Monoclonal Antibodies in Lymphomas -- Role of Apoptosis in Anti-Angiogenic Cancer Therapies -- Photodynamic Therapy-Induced Apoptosis -- Modulation of TRAIL Signaling for Cancer Therapy
Dimensions
unknown
Edition
2nd ed.
Extent
1 online resource (613 p.)
Form of item
online
Isbn
9781281116895
Media category
computer
Media type code
c
Other control number
10.1007/978-1-59745-221-2
Specific material designation
remote
System control number
  • (CKB)1000000000405446
  • (EBL)371394
  • (OCoLC)808729138
  • (SSID)ssj0000768081
  • (PQKBManifestationID)12387795
  • (PQKBTitleCode)TC0000768081
  • (PQKBWorkID)10742467
  • (PQKB)10691301
  • (SSID)ssj0000104510
  • (PQKBManifestationID)11140829
  • (PQKBTitleCode)TC0000104510
  • (PQKBWorkID)10079345
  • (PQKB)11751942
  • (DE-He213)978-1-59745-221-2
  • (MiAaPQ)EBC371394
  • (EXLCZ)991000000000405446

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