The Resource Animal models of behavior genetics, Jonathan C. Gewirtz, Yong-Kyu Kim, editors

Animal models of behavior genetics, Jonathan C. Gewirtz, Yong-Kyu Kim, editors

Label
Animal models of behavior genetics
Title
Animal models of behavior genetics
Statement of responsibility
Jonathan C. Gewirtz, Yong-Kyu Kim, editors
Contributor
Editor
Subject
Genre
Language
eng
Summary
This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The models highlight genetic causes of core features, or endophenotypes, of developmental, internalizing, and externalizing disorders, as well as dementia. Expert contributors address questions ranging from how suitable species are chosen for study to the costs and benefits of using inbred versus outbred strains, and the effects of housing environment on subject animals. Larger issues addressed include how to evaluate the applicability of animal behavioral models to the human condition and how these models can harness emerging molecular technologies to further our understanding of the genetic basis of mental illness. Included in the coverage: Mating and fighting in Drosophila. Attachment and social bonding. Impulsivity in rodents and humans. Animal models of cognitive decline. Animal models of social cognition. Future directions for animal models in behavioral genetics. A detailed map of where this evolving field is headed, Animal Models of Behavior Genetics shows geneticists, molecular biologists, and cognitive neuroscientists paths beyond established concepts toward a more knowledgeable and collaborative future
Member of
Cataloging source
N$T
Dewey number
591.5
Illustrations
illustrations
Index
index present
LC call number
QH457
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2016 J-248
  • QU 450
http://library.link/vocab/relatedWorkOrContributorName
  • Gewirtz, Jonathan C.
  • Kim, Yong-Kyu
Series statement
Advances in behavior genetics
http://library.link/vocab/subjectName
  • Behavior genetics
  • Animal models in research
  • SCIENCE
  • Animal models in research
  • Behavior genetics
  • Biomedicine
  • Human Genetics
  • Psychiatry
  • Developmental Psychology
  • Neurosciences
  • Genetics, Behavioral
  • Psychiatry
  • Child & developmental psychology
  • Neurosciences
  • Medical genetics
Label
Animal models of behavior genetics, Jonathan C. Gewirtz, Yong-Kyu Kim, editors
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-1-4939-3777-6
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Preface; Acknowledgments; Contents; Contributors; Part I: Animal Models of Normative Behavior; Chapter 1: Male Fruit Fly's Courtship and Its Double Control by the€Fruitless and Doublesex Genes; Introduction; Current Research; The Field of€Mating Research Began with Fruitless; A Muscle Tells About the€Sex of€the€Brain; An RNA Splicing Difference Determines the Fly's Sex; Molecular Identification of€the€fru Gene; Some fru-Expressing Neurons are Sexually Dimorphic; The Mechanisms by Which Fru Generates Sex Differences in€Neurons; Some Neurons are Present Only in€the€Female or Male Brain
  • Do Flies with€Sexually Mosaic Brains Behave as€Female or Male? Which Part of€the€Brain Needs to€be€Male for€the€Fly to€Behave as€a€Male?; Which Cells in€the€Male's Brain Decide to Court?; Forced Activation of€P1 Triggers Courtship Behavior in€a€Solitary Male; P1 Neurons Are Activated Upon Female Contact; The Motor Center for€Courtship Song Generation; Dsx is Required for€Sine Song Production; Sensory Control of€Courtship Behavior; Gustatory Receptors for€Nonvolatile Pheromone Sensation; Ligand-Activated Channels as€Mediators of Pheromonal Communication
  • Circuitry for€Gustatory Pheromone Processing The Olfactory System Regulating Courtship Behavior; Inhibitory Pheromone Inputs Modulate the€Decision to€Court; Auditory Input Affects Male Courtship; Experience Modulates Innate Courtship Behavior; Conclusion; References; Chapter 2: A Drosophila Model for€Aggression; Introduction; Current Research; Ecological and Evolutionary Perspectives; Territoriality; Mate Competition; Aggressive Behavior; Neurological and Genetic Perspectives; Social Experience and€Behavior; Mushroom Bodies as€a€Site for€Associative Learning
  • Genetics of Aggressive Behavior Future Directions; References; Chapter 3: The Genetics of Impulsivity: A Synthesis of Findings in Humans and Rodent Models; Introduction; Heritability of€Impulsivity; Genes Influencing Impulsivity; Dopamine Receptor Genes; Serotonin Receptor Genes; Noradrenaline Receptor Genes; Monoaminergic Metabolic Markers; Non-monoaminergic Substrates; Future Directions; Studies in€Animal Models of€Impulsivity; Genome-Wide Association Studies; Neuroimaging Genetics; Conclusions; References
  • Chapter 4: The Neurobiology and Genetics of Affiliation and Social Bonding in Animal Models Introduction; Current Research; The Molecules of€Affiliation and€Social Bonding; Social Recognition; Infant-Mother Attachment; Maternal Nurturing; Pair Bonding; Human Implications and€Translational Opportunities; Conclusions and€Future Directions; References; Part II: Animal Models of Cognitive Processes and Cognitive Decline; Chapter 5: Intellectual Disability; Introduction; Contribution of€Organism Models to€a€Translational Strategy for€ID; Criteria for€Developing Organism Models of€ID
Dimensions
unknown
Extent
1 online resource (xvi, 389 pages)
File format
unknown
Form of item
online
Isbn
9781493937776
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-1-4939-3777-6
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)956539500
  • (OCoLC)ocn956539500
Label
Animal models of behavior genetics, Jonathan C. Gewirtz, Yong-Kyu Kim, editors
Link
https://ezproxy.lib.ou.edu/login?url=http://link.springer.com/10.1007/978-1-4939-3777-6
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Preface; Acknowledgments; Contents; Contributors; Part I: Animal Models of Normative Behavior; Chapter 1: Male Fruit Fly's Courtship and Its Double Control by the€Fruitless and Doublesex Genes; Introduction; Current Research; The Field of€Mating Research Began with Fruitless; A Muscle Tells About the€Sex of€the€Brain; An RNA Splicing Difference Determines the Fly's Sex; Molecular Identification of€the€fru Gene; Some fru-Expressing Neurons are Sexually Dimorphic; The Mechanisms by Which Fru Generates Sex Differences in€Neurons; Some Neurons are Present Only in€the€Female or Male Brain
  • Do Flies with€Sexually Mosaic Brains Behave as€Female or Male? Which Part of€the€Brain Needs to€be€Male for€the€Fly to€Behave as€a€Male?; Which Cells in€the€Male's Brain Decide to Court?; Forced Activation of€P1 Triggers Courtship Behavior in€a€Solitary Male; P1 Neurons Are Activated Upon Female Contact; The Motor Center for€Courtship Song Generation; Dsx is Required for€Sine Song Production; Sensory Control of€Courtship Behavior; Gustatory Receptors for€Nonvolatile Pheromone Sensation; Ligand-Activated Channels as€Mediators of Pheromonal Communication
  • Circuitry for€Gustatory Pheromone Processing The Olfactory System Regulating Courtship Behavior; Inhibitory Pheromone Inputs Modulate the€Decision to€Court; Auditory Input Affects Male Courtship; Experience Modulates Innate Courtship Behavior; Conclusion; References; Chapter 2: A Drosophila Model for€Aggression; Introduction; Current Research; Ecological and Evolutionary Perspectives; Territoriality; Mate Competition; Aggressive Behavior; Neurological and Genetic Perspectives; Social Experience and€Behavior; Mushroom Bodies as€a€Site for€Associative Learning
  • Genetics of Aggressive Behavior Future Directions; References; Chapter 3: The Genetics of Impulsivity: A Synthesis of Findings in Humans and Rodent Models; Introduction; Heritability of€Impulsivity; Genes Influencing Impulsivity; Dopamine Receptor Genes; Serotonin Receptor Genes; Noradrenaline Receptor Genes; Monoaminergic Metabolic Markers; Non-monoaminergic Substrates; Future Directions; Studies in€Animal Models of€Impulsivity; Genome-Wide Association Studies; Neuroimaging Genetics; Conclusions; References
  • Chapter 4: The Neurobiology and Genetics of Affiliation and Social Bonding in Animal Models Introduction; Current Research; The Molecules of€Affiliation and€Social Bonding; Social Recognition; Infant-Mother Attachment; Maternal Nurturing; Pair Bonding; Human Implications and€Translational Opportunities; Conclusions and€Future Directions; References; Part II: Animal Models of Cognitive Processes and Cognitive Decline; Chapter 5: Intellectual Disability; Introduction; Contribution of€Organism Models to€a€Translational Strategy for€ID; Criteria for€Developing Organism Models of€ID
Dimensions
unknown
Extent
1 online resource (xvi, 389 pages)
File format
unknown
Form of item
online
Isbn
9781493937776
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Note
SpringerLink
Other control number
10.1007/978-1-4939-3777-6
Other physical details
illustrations (some color).
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)956539500
  • (OCoLC)ocn956539500

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