The Resource Advances in Ocular Toxicology, edited by Keith Green, Henry F. Edelhauser, David S. Hull, David E. Potter, Ramesh C. Tripathi, (electronic resource)

Advances in Ocular Toxicology, edited by Keith Green, Henry F. Edelhauser, David S. Hull, David E. Potter, Ramesh C. Tripathi, (electronic resource)

Label
Advances in Ocular Toxicology
Title
Advances in Ocular Toxicology
Statement of responsibility
edited by Keith Green, Henry F. Edelhauser, David S. Hull, David E. Potter, Ramesh C. Tripathi
Title variation
Proceedings of the Fifth Congress of the International Society of Toxicology held in Asheville, North Carolina, October 13-17, 1996
Contributor
Editor
Editor
Subject
Language
  • eng
  • eng
Summary
This volume represents the proceedings of the Fifth Congress of the International Society of Ocular Toxicology (ISOT), which was held at the Grove Park Inn and Resort in Asheville, North Carolina, October 13-17, 1996. We are delighted to present this volume to the ophthalmic community, especially those with a significant interest in ocular toxicol­ogy. The Fifth Congress was developed around themes relating to ocular drug metabolism, the ocular pathophysiological effects of nitric oxide, government issues relating to the use of alternative methods for toxicity testing, and a workshop that encompassed comparisons of both in vitro versus in vivo models as well as different animal models. The outcome of this congress, embodied in this volume, is a contribution to the methodologies currently employed or under development and to various drug or physical effects on different ocular tissues. While the focus of this proceedings is on ocular effects of drugs or other materials, many of the contributions deal with topics that have a much broader interest. The workshop concerning the use of different model systems and the choice of the best animal model for drug testing covers a wide range of interests that ex­tends far beyond specific ocular effects. This is especially true in the area of alternative methods and in the choice of the best animal model for examination of different disease entities
Dewey number
  • 571.31
  • 610
  • 615
  • 617.71
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
  • dZcYy_MsVu8
  • 8Jyt2rzByJ0
  • jyUwsedQ0as
  • 3P-OHPc2tNE
  • DvL9i8AtUtI
Language note
English
LC call number
RM1-950
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Green, Keith.
  • Edelhauser, Henry F.
  • Hull, David S.
  • Potter, David E.
  • Tripathi, Ramesh C.
Series statement
Language of science
http://library.link/vocab/subjectName
  • Toxicology
  • Morphology (Animals)
  • Pharmacology/Toxicology
  • Animal Anatomy / Morphology / Histology
Label
Advances in Ocular Toxicology, edited by Keith Green, Henry F. Edelhauser, David S. Hull, David E. Potter, Ramesh C. Tripathi, (electronic resource)
Instantiates
Publication
Note
"Proceedings of the Fifth Congress of the International Society of Ocular Toxicology, held October 13-17, 1996, in Asheville, North Carolina"--T.p. verso
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Welcome and Opening of Congress -- 1. Cytochrome P450 and Arachidonic Acid Metabolism in the Corneal Epithelium: Role in Inflammation -- 2. The Effects of 12(R)HETE and Its Metabolite 8(R)HHDTrE on Corneal Endothelial Function -- 3. Protein-Thiol Mixed Disulfides and Thioltransferase in the Lens: A Review.... -- 4. Corneal Lesions in Beagle Dogs Given Oral 5-Ethynyluracil Followed by 5-Fluorouracil -- 5. Corneal Damage following Continuous Infusion in Rats: Possible Explanation and Preventative Measures -- 6. Ultraviolet Light-Induced Damage in Rabbit Corneal Epithelial Cellsin VitroProtection with Absorption Filters -- 7. The Effects ofad Libitum(AL) Overfeeding and Moderate Dietary Restriction (DR) on the Incidence of Spontaneous Corneal Dystrophy in Control Sprague-Dawley (SD) Rats -- 8. Barotoxic Effects on Morphology and Viability of Trabecular Cells: A Preliminary Report -- 9. Topical Fluorescein Application Can Induce Iritis and Glaucoma: An Unusual Case Report -- 10. Ocular Toxicity of Sodium Diethylthiocarbamate, DDTC, in the Beagle Dog -- 11. Do Therapeutic Doses of Ethambutol Cause Optic Nerve Toxicity? -- 12. Testing of Ocular Viscoelastics by Injection into the Rabbit Vitreous: Historical Control Data Resulting from Various Dosing Techniques -- 13. Effects of Antiviral Agents on Retinal Function in Vertebrate Retina -- 14. Experimental Implantation of Devices for Electrical Retinal Stimulation in Rabbits: Preliminary Results -- 15. Nitric Oxide in Ocular Inflammation -- 16. Role of Nitric Oxide in Vascular Dysfunction Associated with Ocular Diseases -- 17. Effects of the Inhibition of Nitric Oxide Synthase and Lipoxygenase on the Development of Endotoxin-Induced Uveitis -- 18. Evaluation of Two Rabbit Ocular Implantation Models Using Polymethylmethacrylate Intraocular Lenses -- 19. Characterization of Immortalized Lens Epithelial Cells as a Potentialin VitroAlternative Model for the Cellular Toxicity and the Efficacy Evaluations of Ocular Drug Candidates -- 20. Immortalization and Characterizations of Rabbit Corneal Epithelial Cell Lines as Potentialin VitroAlternative Models for Evaluating the Cellular Toxicity of Ocular Drug Candidates -- 21. Comparison of Somein VitroMeasurements of Membrane Damage to Corneal Epithelial Cells -- 22. Computer-Assisted Evaluation of Iris Color Changes in Primate Toxicity Studies -- 23. Workshop onin Vitroversusin VivoModels for Ocular Toxicity Testing -- 24. Toxicity Testing for Ocular Drug Products -- Participants
Dimensions
unknown
Edition
1st ed. 1997.
Extent
1 online resource (281 p.)
Form of item
online
Isbn
9781461559375
Media category
computer
Media type code
c
Other control number
10.1007/978-1-4615-5937-5
Specific material designation
remote
System control number
  • (CKB)3400000000096405
  • (EBL)1267915
  • (SSID)ssj0000922021
  • (PQKBManifestationID)11461642
  • (PQKBTitleCode)TC0000922021
  • (PQKBWorkID)10848372
  • (PQKB)10026664
  • (SSID)ssj0000805034
  • (PQKBManifestationID)12379321
  • (PQKBTitleCode)TC0000805034
  • (PQKBWorkID)10823185
  • (PQKB)11469758
  • (DE-He213)978-1-4615-5937-5
  • (MiAaPQ)EBC1267915
  • (EXLCZ)993400000000096405
Label
Advances in Ocular Toxicology, edited by Keith Green, Henry F. Edelhauser, David S. Hull, David E. Potter, Ramesh C. Tripathi, (electronic resource)
Publication
Note
"Proceedings of the Fifth Congress of the International Society of Ocular Toxicology, held October 13-17, 1996, in Asheville, North Carolina"--T.p. verso
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Welcome and Opening of Congress -- 1. Cytochrome P450 and Arachidonic Acid Metabolism in the Corneal Epithelium: Role in Inflammation -- 2. The Effects of 12(R)HETE and Its Metabolite 8(R)HHDTrE on Corneal Endothelial Function -- 3. Protein-Thiol Mixed Disulfides and Thioltransferase in the Lens: A Review.... -- 4. Corneal Lesions in Beagle Dogs Given Oral 5-Ethynyluracil Followed by 5-Fluorouracil -- 5. Corneal Damage following Continuous Infusion in Rats: Possible Explanation and Preventative Measures -- 6. Ultraviolet Light-Induced Damage in Rabbit Corneal Epithelial Cellsin VitroProtection with Absorption Filters -- 7. The Effects ofad Libitum(AL) Overfeeding and Moderate Dietary Restriction (DR) on the Incidence of Spontaneous Corneal Dystrophy in Control Sprague-Dawley (SD) Rats -- 8. Barotoxic Effects on Morphology and Viability of Trabecular Cells: A Preliminary Report -- 9. Topical Fluorescein Application Can Induce Iritis and Glaucoma: An Unusual Case Report -- 10. Ocular Toxicity of Sodium Diethylthiocarbamate, DDTC, in the Beagle Dog -- 11. Do Therapeutic Doses of Ethambutol Cause Optic Nerve Toxicity? -- 12. Testing of Ocular Viscoelastics by Injection into the Rabbit Vitreous: Historical Control Data Resulting from Various Dosing Techniques -- 13. Effects of Antiviral Agents on Retinal Function in Vertebrate Retina -- 14. Experimental Implantation of Devices for Electrical Retinal Stimulation in Rabbits: Preliminary Results -- 15. Nitric Oxide in Ocular Inflammation -- 16. Role of Nitric Oxide in Vascular Dysfunction Associated with Ocular Diseases -- 17. Effects of the Inhibition of Nitric Oxide Synthase and Lipoxygenase on the Development of Endotoxin-Induced Uveitis -- 18. Evaluation of Two Rabbit Ocular Implantation Models Using Polymethylmethacrylate Intraocular Lenses -- 19. Characterization of Immortalized Lens Epithelial Cells as a Potentialin VitroAlternative Model for the Cellular Toxicity and the Efficacy Evaluations of Ocular Drug Candidates -- 20. Immortalization and Characterizations of Rabbit Corneal Epithelial Cell Lines as Potentialin VitroAlternative Models for Evaluating the Cellular Toxicity of Ocular Drug Candidates -- 21. Comparison of Somein VitroMeasurements of Membrane Damage to Corneal Epithelial Cells -- 22. Computer-Assisted Evaluation of Iris Color Changes in Primate Toxicity Studies -- 23. Workshop onin Vitroversusin VivoModels for Ocular Toxicity Testing -- 24. Toxicity Testing for Ocular Drug Products -- Participants
Dimensions
unknown
Edition
1st ed. 1997.
Extent
1 online resource (281 p.)
Form of item
online
Isbn
9781461559375
Media category
computer
Media type code
c
Other control number
10.1007/978-1-4615-5937-5
Specific material designation
remote
System control number
  • (CKB)3400000000096405
  • (EBL)1267915
  • (SSID)ssj0000922021
  • (PQKBManifestationID)11461642
  • (PQKBTitleCode)TC0000922021
  • (PQKBWorkID)10848372
  • (PQKB)10026664
  • (SSID)ssj0000805034
  • (PQKBManifestationID)12379321
  • (PQKBTitleCode)TC0000805034
  • (PQKBWorkID)10823185
  • (PQKB)11469758
  • (DE-He213)978-1-4615-5937-5
  • (MiAaPQ)EBC1267915
  • (EXLCZ)993400000000096405

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