The Resource Advances from phage to humans, edited by Jac A. Nickoloff and Merl F. Hoekstra, (electronic resource)

Advances from phage to humans, edited by Jac A. Nickoloff and Merl F. Hoekstra, (electronic resource)

Label
Advances from phage to humans
Title
Advances from phage to humans
Statement of responsibility
edited by Jac A. Nickoloff and Merl F. Hoekstra
Contributor
Subject
Genre
Language
eng
Summary
In recent years it has become increasingly apparent that DNA repair processes play key roles in protecting genome integrity, where the failure of repair systems is directly responsible for many, if not the majority of, cancers. In DNA Damage and Repair, Vol. III: Advances from Phage to Humans, Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eukaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair proteins and teleomere function, and the roles of BRCA1 and BRCA2 in DNA repair. The contributors make every effort to integrate the basic experimental information with clinical aspects of cancer biology as they relate to DNA repair. Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, offering broad integrated coverage that will help researchers understand the important functional relationships among different DNA repair pathways, as well as the relationships among DNA repair pathways, cancer etiology, and cancer therapies
Member of
Cataloging source
E7B
Dewey number
572.8/6
Illustrations
illustrations
Index
index present
LC call number
QH467
LC item number
.D15 2001eb
Literary form
non fiction
Nature of contents
  • standards specifications
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Nickoloff, Jac A
  • Hoekstra, Merl F
Series statement
  • Contemporary cancer research
  • DNA damage and repair
Series volume
3
http://library.link/vocab/subjectName
  • DNA repair
  • Biochemical genetics
  • Biochemical genetics
  • DNA repair
  • Biochemical genetics
  • DNA repair
  • Electronic books. -- local
Label
Advances from phage to humans, edited by Jac A. Nickoloff and Merl F. Hoekstra, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-095-7
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Color
multicolored
Contents
1 DNA Repair in Bacteriophage -- 2 Post-Replication Repair: A New Perspective Focusing on the Coordination Between Recombination and DNA Replication -- 3 Abasic Site Repair in Higher Eukaryotes -- 4 Structure and Functions of the Major Human AP Endonuclease HAP1 /Ref-1 -- 5 Mating-Type Control of DNA Repair and Recombination in Saccharomyces cerevisiae -- 6 DNA End-Processing and Heteroduplex DNA Formation During Recombinational Repair of DNA Double-Strand Breaks -- 7 The MRE11-RAD50 Complex: Diverse Functions in the Cellular DNA Damage Response -- 8 Repair of DNA Double-Strand Breaks and Mismatches in Drosophila -- 9 Double-Strand Break Repair and Homologous Recombination in Mammalian Cells -- 10 BRCA1 and BRCA2 in DNA Repair and Genome Stability -- 11 DNA Repair and the Generation of Immune Diversity: The Agony and the Ecstasy -- 12 Interaction of Cell-Cycle Checkpoints with Muscle Differentiation -- 13 Ultraviolet Light-Induced and Spontaneous Recombination in Eukaryotes: Roles of DNA Damage and DNA Repair Proteins -- 14 Telomeres, DNA Repair Proteins, and Making Ends Meet -- 15 Conservation of Eukaryotic DNA Repair Mechanisms
Dimensions
unknown
Extent
1 online resource (xiv, 411 p.)
Form of item
online
Isbn
9781592590957
Isbn Type
(electronic bk.)
Other physical details
ill.
Specific material designation
remote
System control number
  • (OCoLC)648272522
  • (OCoLC)ocn648272522
Label
Advances from phage to humans, edited by Jac A. Nickoloff and Merl F. Hoekstra, (electronic resource)
Link
http://dx.doi.org/10.1007/978-1-59259-095-7
Publication
Bibliography note
Includes bibliographical references and index
Color
multicolored
Contents
1 DNA Repair in Bacteriophage -- 2 Post-Replication Repair: A New Perspective Focusing on the Coordination Between Recombination and DNA Replication -- 3 Abasic Site Repair in Higher Eukaryotes -- 4 Structure and Functions of the Major Human AP Endonuclease HAP1 /Ref-1 -- 5 Mating-Type Control of DNA Repair and Recombination in Saccharomyces cerevisiae -- 6 DNA End-Processing and Heteroduplex DNA Formation During Recombinational Repair of DNA Double-Strand Breaks -- 7 The MRE11-RAD50 Complex: Diverse Functions in the Cellular DNA Damage Response -- 8 Repair of DNA Double-Strand Breaks and Mismatches in Drosophila -- 9 Double-Strand Break Repair and Homologous Recombination in Mammalian Cells -- 10 BRCA1 and BRCA2 in DNA Repair and Genome Stability -- 11 DNA Repair and the Generation of Immune Diversity: The Agony and the Ecstasy -- 12 Interaction of Cell-Cycle Checkpoints with Muscle Differentiation -- 13 Ultraviolet Light-Induced and Spontaneous Recombination in Eukaryotes: Roles of DNA Damage and DNA Repair Proteins -- 14 Telomeres, DNA Repair Proteins, and Making Ends Meet -- 15 Conservation of Eukaryotic DNA Repair Mechanisms
Dimensions
unknown
Extent
1 online resource (xiv, 411 p.)
Form of item
online
Isbn
9781592590957
Isbn Type
(electronic bk.)
Other physical details
ill.
Specific material designation
remote
System control number
  • (OCoLC)648272522
  • (OCoLC)ocn648272522

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